Safety, tolerability and efficacy of the glutaminyl cyclase inhibitor PQ912 in Alzheimer’s disease: results of a randomized, double-blind, placebo-controlled phase 2a study

Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy

(2017) Torsten Hoffmann et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

EEG spectral analysis as a putative early prognostic biomarker in nondemented, amyloid positive subjects

(2017) Alida A. Gouw et al.   NEUROBIOLOGY OF AGING

GANTENERUMAB TREATMENT REDUCES BIOMARKERS OF NEURONAL AND SYNAPTIC DEGENERATION IN ALZHEIMER’S DISEASE

(2016) Kaj Blennow et al.   Alzheimers & Dementia

CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis

(2016) Bob Olsson et al.   LANCET NEUROLOGY

Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer’s disease

(2015) Maike Hartlage-Rübsamen et al.   ACTA NEUROPATHOLOGICA

2015 Alzheimer's disease facts and figures

(2015)   Alzheimers & Dementia

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

The minimum spanning tree: An unbiased method for brain network analysis

(2015) P. Tewarie et al.   NEUROIMAGE

Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer’s disease

(2015) Konstantin Hellwig et al.   Alzheimers Research & Therapy

The trees and the forest: Characterization of complex brain networks with minimum spanning trees

(2014) C.J. Stam et al.   INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY

Pyroglutamylated Amyloid-β Peptide Reverses Cross β-Sheets by a Prion-Like Mechanism

(2014) Jason O. Matos et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Activity and Architecture of Pyroglutamate-Modified Amyloid-β (AβpE3-42) Pores

(2014) Alan L. Gillman et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

Brain network alterations in Alzheimer's disease measured by Eigenvector centrality in fMRI are related to cognition and CSF biomarkers

(2013) Maja A.A. Binnewijzend et al.   HUMAN BRAIN MAPPING

Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study

(2013) Victor L Villemagne et al.   LANCET NEUROLOGY

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β

(2012) Justin M. Nussbaum et al.   NATURE

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Young Alzheimer patients show distinct regional changes of oscillatory brain dynamics

(2011) Hanneke de Waal et al.   NEUROBIOLOGY OF AGING

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY