Role of Ketogenic Diets in Neurodegenerative Diseases (Alzheimer’s Disease and Parkinson’s Disease)

Octanoic acid prevents reduction of striatal dopamine in the MPTP mouse model of Parkinson's disease.

(2018) Ilona Joniec-Maciejak et al.   Pharmacological Reports

Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice

(2018) David Ma et al.   Scientific Reports

Low-fat versus ketogenic diet in Parkinson's disease: A pilot randomized controlled trial

(2018) Matthew C.L. Phillips et al.   MOVEMENT DISORDERS

Effects of a medium-chain triglyceride-based ketogenic formula on cognitive function in patients with mild-to-moderate Alzheimer’s disease

(2018) Miho Ota et al.   NEUROSCIENCE LETTERS

Metabolic Dysfunctions in Amyotrophic Lateral Sclerosis Pathogenesis and Potential Metabolic Treatments

(2017) Tesfaye W. Tefera et al.   Frontiers in Neuroscience

Novel ketone diet enhances physical and cognitive performance

(2016) Andrew J. Murray et al.   FASEB JOURNAL

The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease: A Mini Review

(2016) Shanmugam Manoharan et al.   Oxidative Medicine and Cellular Longevity

High fat diet exacerbates Alzheimer’s disease-related pathology in APPswe/PS1 mice

(2016) Peter Thériault et al.   Oncotarget

Ketones Prevent Oxidative Impairment of Hippocampal Synaptic Integrity through KATP Channels

(2015) Do Young Kim et al.   PLoS One

The collective therapeutic potential of cerebral ketone metabolism in traumatic brain injury

(2014) Mayumi L. Prins et al.   JOURNAL OF LIPID RESEARCH

Saturated and trans fats and dementia: a systematic review

(2014) Neal D. Barnard et al.   NEUROBIOLOGY OF AGING

Ketogenic Diet for Obesity: Friend or Foe?

(2014) Antonio Paoli   International Journal of Environmental Research and Public Health

Ketogenic Diet in Neuromuscular and Neurodegenerative Diseases

(2014) Antonio Paoli et al.   Biomed Research International

A ketogenic diet improves motor performance but does not affect β-amyloid levels in a mouse model of Alzheimer's Disease

(2013) Tina L. Beckett et al.   BRAIN RESEARCH

Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets

(2013) A Paoli et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Evidence-Based Recommendations for Optimal Dietary Protein Intake in Older People: A Position Paper From the PROT-AGE Study Group

(2013) Jürgen Bauer et al.   Journal of the American Medical Directors Association

Ketogenic Diet Improves Motor Performance but Not Cognition in Two Mouse Models of Alzheimer’s Pathology

(2013) Milene L. Brownlow et al.   PLoS One

Ketogenic diets

(2012) Eric H. Kossoff et al.   CURRENT OPINION IN NEUROLOGY

A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease

(2012) Yoshihiro Kashiwaya et al.   NEUROBIOLOGY OF AGING

Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects

(2012) Kieran Clarke et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

The Ketogenic Diet as a Treatment Paradigm for Diverse Neurological Disorders

(2012) Carl E. Stafstrom et al.   Frontiers in Pharmacology

HIgh dietary and plasma levels of the omega-3 fatty acid docosahexaenoic acid are associated with decreased dementia risk: the rancho bernardo study

(2011) L. B. Lopez et al.   Journal of Nutrition Health & Aging

Neuroprotective and Anti-inflammatory Activities of Ketogenic Diet on MPTP-induced Neurotoxicity

(2010) Xinxin Yang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Ketones prevent synaptic dysfunction induced by mitochondrial respiratory complex inhibitors

(2010) Do Young Kim et al.   JOURNAL OF NEUROCHEMISTRY

Dietary ketosis enhances memory in mild cognitive impairment

(2010) Robert Krikorian et al.   NEUROBIOLOGY OF AGING

Ketogenic diet protects dopaminergic neurons against 6-OHDA neurotoxicity via up-regulating glutathione in a rat model of Parkinson's disease

(2009) Baohua Cheng et al.   BRAIN RESEARCH

Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial

(2009) Samuel T Henderson et al.   Nutrition & Metabolism

Induction of ketosis may improve mitochondrial function and decrease steady-state amyloid-β precursor protein (APP) levels in the aged dog

(2008) Christa M. Studzinski et al.   BRAIN RESEARCH

The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies

(2008) Marwan Maalouf et al.   BRAIN RESEARCH REVIEWS