Targeting the DNA Repair Endonuclease ERCC1-XPF with Green Tea Polyphenol Epigallocatechin-3-Gallate (EGCG) and Its Prodrug to Enhance Cisplatin Efficacy in Human Cancer Cells

Epigallocatechin gallate sensitizes cisplatin-resistant oral cancer CAR cell apoptosis and autophagy through stimulating AKT/STAT3 pathway and suppressing multidrug resistance 1 signaling

(2016) Chien-Han Yuan et al.   ENVIRONMENTAL TOXICOLOGY

Identification of small molecule inhibitors of ERCC1-XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells

(2016) Sanjeevani Arora et al.   Oncotarget

Catechols and 3-hydroxypyridones as inhibitors of the DNA repair complex ERCC1-XPF

(2015) Timothy M. Chapman et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

N-Hydroxyimides and hydroxypyrimidinones as inhibitors of the DNA repair complex ERCC1–XPF

(2015) Timothy M. Chapman et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition of the ERCC1–XPF structure-specific endonuclease to overcome cancer chemoresistance

(2015) Ewan M. McNeil et al.   DNA REPAIR

EGCG synergizes the therapeutic effect of cisplatin and oxaliplatin through autophagic pathway in human colorectal cancer cells

(2015) Fen Hu et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Why is Tanimoto index an appropriate choice for fingerprint-based similarity calculations?

(2015) Dávid Bajusz et al.   Journal of Cheminformatics

EGCG Enhances Cisplatin Sensitivity by Regulating Expression of the Copper and Cisplatin Influx Transporter CTR1 in Ovary Cancer

(2015) Xuemin Wang et al.   PLoS One

Mechanism and regulation of incisions during DNA interstrand cross-link repair

(2014) Jieqiong Zhang et al.   DNA REPAIR

Randomized International Phase III Trial of ERCC1 and RRM1 Expression–Based Chemotherapy Versus Gemcitabine/Carboplatin in Advanced Non–Small-Cell Lung Cancer

(2013) Gerold Bepler et al.   JOURNAL OF CLINICAL ONCOLOGY

ERCC1 Isoform Expression and DNA Repair in Non–Small-Cell Lung Cancer

(2013) Luc Friboulet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epistatic role of base excision repair and mismatch repair pathways in mediating cisplatin cytotoxicity

(2013) Anbarasi Kothandapani et al.   NUCLEIC ACIDS RESEARCH

DNA repair endonuclease ERCC1-XPF as a novel therapeutic target to overcome chemoresistance in cancer therapy

(2012) E. M. McNeil et al.   NUCLEIC ACIDS RESEARCH

Green Tea Polyphenols as Proteasome Inhibitors: Implication in Chemoprevention

(2011) H. Yang et al.   CURRENT CANCER DRUG TARGETS

Downregulation of XPF–ERCC1 enhances cisplatin efficacy in cancer cells☆

(2010) Sanjeevani Arora et al.   DNA REPAIR

Multiple roles of ERCC1-XPF in mammalian interstrand crosslink repair

(2010) Jennifer J. Rahn et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

DNA interstrand crosslink repair in mammalian cells: step by step

(2009) Parameswary A Muniandy et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Identification and Characterization of Inhibitors of Human Apurinic/apyrimidinic Endonuclease APE1

(2009) Anton Simeonov et al.   PLoS One

Pseudoirreversible Inhibition of Prostate-Specific Membrane Antigen by Phosphoramidate Peptidomimetics†

(2008) Tiancheng Liu et al.   BIOCHEMISTRY