WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation

Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development

(2016) Jong-Chan Park et al.   JOURNAL OF CELL SCIENCE

IL-33/ST2 pathway in a bleomycin-induced pulmonary fibrosis model

(2016) Jiao Xu et al.   Molecular Medicine Reports

Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation

(2016) Pu-Hyeon Cha et al.   Nature Chemical Biology

Ras protein expression as a marker for breast cancer

(2016) GLORIA M. CALAF et al.   Oncology Letters

Optimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblotting

(2015) Christoph H. Emmerich et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation

(2015) Ze-Yi Zheng et al.   Cell Reports

KRAS Protein Stability Is Regulated through SMURF2: UBCH5 Complex-Mediated β-TrCP1 Degradation

(2015) Shirish Shukla et al.   NEOPLASIA

Role of Oncogenic K-Ras in Cancer Stem Cell Activation by Aberrant Wnt/β-Catenin Signaling

(2014) Byoung-San Moon et al.   JNCI-Journal of the National Cancer Institute

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

USP29 controls the stability of checkpoint adaptor Claspin by deubiquitination

(2014) Y Martín et al.   ONCOGENE

IHC Profiler: An Open Source Plugin for the Quantitative Evaluation and Automated Scoring of Immunohistochemistry Images of Human Tissue Samples

(2014) Frency Varghese et al.   PLoS One

Impeded Nedd4-1-Mediated Ras Degradation Underlies Ras-Driven Tumorigenesis

(2014) Taoling Zeng et al.   Cell Reports

HectD1 E3 Ligase Modifies Adenomatous Polyposis Coli (APC) with Polyubiquitin to Promote the APC-Axin Interaction

(2013) Hoanh Tran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

UBE4B Protein Couples Ubiquitination and Sorting Machineries to Enable Epidermal Growth Factor Receptor (EGFR) Degradation

(2013) Natalie Sirisaengtaksin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

(2012) Sandra Misale et al.   NATURE

Ras Stabilization Through Aberrant Activation of Wnt/ -Catenin Signaling Promotes Intestinal Tumorigenesis

(2012) W.-J. Jeong et al.   Science Signaling

Expression and prognostic role of pan-Ras, Raf-1, pMEK1 and pERK1/2 in patients with hepatocellular carcinoma

(2011) L. Chen et al.   EJSO

Regulation of p53 stability and function by the deubiquitinating enzyme USP42

(2011) Andreas K Hock et al.   EMBO JOURNAL

AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2,

(2011) Coral Ho et al.   HEPATOLOGY

Regulating the regulator: post-translational modification of RAS

(2011) Ian M. Ahearn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MEK1/2 Inhibitors AS703026 and AZD6244 May Be Potential Therapies forKRASMutated Colorectal Cancer That Is Resistant to EGFR Monoclonal Antibody Therapy

(2010) Juyong Yoon et al.   CANCER RESEARCH

Inactivation of Ras GTPase-activating proteins promotes unrestrained activity of wild-type Ras in human liver cancer

(2010) Diego F. Calvisi et al.   JOURNAL OF HEPATOLOGY

Experimental mouse models for hepatocellular carcinoma research

(2009) Femke Heindryckx et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

H-Ras is degraded by Wnt/ -catenin signaling via  -TrCP-mediated polyubiquitylation

(2009) S.-E. Kim et al.   JOURNAL OF CELL SCIENCE

Ras oncogenes: split personalities

(2008) Antoine E. Karnoub et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY