Shifts in the selectivity filter dynamics cause modal gating in K+ channels

High-resolution NMR studies of antibiotics in cellular membranes

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Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation

(2017) Jing Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen bond strength in membrane proteins probed by time-resolved 1 H-detected solid-state NMR and MD simulations

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Structure of outer membrane protein G in lipid bilayers

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The gating cycle of a K+ channel at atomic resolution

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Emergence of ion channel modal gating from independent subunit kinetics

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Structure of fully protonated proteins by proton-detected magic-angle spinning NMR

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Instantaneous ion configurations in the K+ion channel selectivity filter revealed by 2D IR spectroscopy

(2016) Huong T. Kratochvil et al.   SCIENCE

Atomic mutagenesis in ion channels with engineered stoichiometry

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Modal gating of endplate acetylcholine receptors: A proposed mechanism

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De Novo 3D Structure Determination from Sub-milligram Protein Samples by Solid-State 100 kHz MAS NMR Spectroscopy

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Conformational Dynamics of a Seven Transmembrane Helical Protein Anabaena Sensory Rhodopsin Probed by Solid-State NMR

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Quantitative Analysis of the Water Occupancy around the Selectivity Filter of a K+ Channel in Different Gating Modes

(2014) Markus Weingarth et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ion permeation in K+ channels occurs by direct Coulomb knock-on

(2014) D. A. Kopfer et al.   SCIENCE

Advances in Solid-State Relaxation Methodology for Probing Site-Specific Protein Dynamics

(2013) Józef Romuald Lewandowski   ACCOUNTS OF CHEMICAL RESEARCH

Structural Determinants of Specific Lipid Binding to Potassium Channels

(2013) Markus Weingarth et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recovery from slow inactivation in K+ channels is controlled by water molecules

(2013) Jared Ostmeyer et al.   NATURE

Transmembrane allosteric coupling of the gates in a potassium channel

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Importance of lipid-pore loop interface for potassium channel structure and function

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Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

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Protonation state of E71 in KcsA and its role for channel collapse and inactivation

(2012) M. P. Bhate et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Voltage Gating in Potassium Channels

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Mechanism for Selectivity-Inactivation Coupling in KcsA Potassium Channels

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A Multipoint Hydrogen-Bond Network Underlying KcsA C-Type Inactivation

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Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations

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Site-Specific Measurement of Slow Motions in Proteins

(2011) Józef R. Lewandowski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism for selectivity-inactivation coupling in KcsA potassium channels

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Conformation of a Seven-Helical Transmembrane Photosensor in the Lipid Environment

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A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain

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Broadband magnetization transfer using moderate radio-frequency fields for NMR with very high static fields and spinning speeds

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SPARTA+: a modest improvement in empirical NMR chemical shift prediction by means of an artificial neural network

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Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

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Structural basis for the coupling between activation and inactivation gates in K+ channels

(2010) Luis G. Cuello et al.   NATURE

On the structural basis of modal gating behavior in K+ channels

(2010) Sudha Chakrapani et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CHARMM-GUI Membrane Builder for Mixed Bilayers and Its Application to Yeast Membranes

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Low-power decoupling at high spinning frequencies in high static fields

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CHARMM-GUI: A web-based graphical user interface for CHARMM

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A structural link between inactivation and block of a K+ channel

(2008) Christian Ader et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY