High-resolution NMR studies of antibiotics in cellular membranes

The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors

(2018) Lisa Joedicke et al.   Nature Chemical Biology

Line-Broadening in Low-Temperature Solid-State NMR Spectra of Fibrils

(2017) Thomas Bauer et al.   JOURNAL OF BIOMOLECULAR NMR

Peptide and Protein Dynamics and Low-Temperature/DNP Magic Angle Spinning NMR

(2017) Qing Zhe Ni et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Efficient assignment and NMR analysis of an intact virus using sequential side-chain correlations and DNP sensitization

(2017) Ivan V. Sergeyev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic nuclear polarization for sensitivity enhancement in modern solid-state NMR

(2017) Aany Sofia Lilly Thankamony et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Hydrogen bond strength in membrane proteins probed by time-resolved 1 H-detected solid-state NMR and MD simulations

(2017) João Medeiros-Silva et al.   SOLID STATE NUCLEAR MAGNETIC RESONANCE

Incorporation of tryptophan analogues into the lantibiotic nisin

(2016) Liang Zhou et al.   AMINO ACIDS

1 H-Detected Solid-State NMR Studies of Water-Inaccessible Proteins In Vitro and In Situ

(2016) João Medeiros-Silva et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

EGFR Dynamics Change during Activation in Native Membranes as Revealed by NMR

(2016) Mohammed Kaplan et al.   CELL

High resolution observed in 800 MHz DNP spectra of extremely rigid type III secretion needles

(2016) Pascal Fricke et al.   JOURNAL OF BIOMOLECULAR NMR

Efficient DNP NMR of membrane proteins: sample preparation protocols, sensitivity, and radical location

(2016) Shu Y. Liao et al.   JOURNAL OF BIOMOLECULAR NMR

Antimicrobial lipopeptide tridecaptin A1selectively binds to Gram-negative lipid II

(2016) Stephen A. Cochrane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Situ Structural Studies of Anabaena Sensory Rhodopsin in the E. coli Membrane

(2015) Meaghan E. Ward et al.   BIOPHYSICAL JOURNAL

Sensitivity-Enhanced NMR Reveals Alterations in Protein Structure by Cellular Milieus

(2015) Kendra K. Frederick et al.   CELL

Cysteine-Specific Labeling of Proteins with a Nitroxide Biradical for Dynamic Nuclear Polarization NMR

(2015) Maxim A. Voinov et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Semisynthetic Lipopeptides Derived from Nisin Display Antibacterial Activity and Lipid II Binding on Par with That of the Parent Compound

(2015) Timo Koopmans et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

LipidII: Just Another Brick in the Wall?

(2015) Dirk-Jan Scheffers et al.   PLoS Pathogens

The length of a lantibiotic hinge region has profound influence on antimicrobial activity and host specificity

(2015) Liang Zhou et al.   Frontiers in Microbiology

Structural Variations of the Cell Wall Precursor Lipid II and Their Influence on Binding and Activity of the Lipoglycopeptide Antibiotic Oritavancin

(2014) Daniela Münch et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

NMR-based structural biology enhanced by dynamic nuclear polarization at high magnetic field

(2014) Eline J. Koers et al.   JOURNAL OF BIOMOLECULAR NMR

Highly Efficient, Water-Soluble Polarizing Agents for Dynamic Nuclear Polarization at High Frequency

(2013) Claire Sauvée et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Saturation Mutagenesis of Lysine 12 Leads to the Identification of Derivatives of Nisin A with Enhanced Antimicrobial Activity

(2013) Evelyn M. Molloy et al.   PLoS One

Intensive Mutagenesis of the Nisin Hinge Leads to the Rational Design of Enhanced Derivatives

(2013) Brian Healy et al.   PLoS One

Bioengineered Nisin A Derivatives with Enhanced Activity against Both Gram Positive and Gram Negative Pathogens

(2012) Des Field et al.   PLoS One

Cellular solid-state nuclear magnetic resonance spectroscopy

(2012) M. Renault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and in vitro Analysis of the GatD/MurT Enzyme-Complex Catalyzing Lipid II Amidation in Staphylococcus aureus

(2012) Daniela Münch et al.   PLoS Pathogens

Role of Lipid II and Membrane Thickness in the Mechanism of Action of the Lantibiotic Bovicin HC5

(2011) Aline Dias Paiva et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Neurotoxin II Bound to Acetylcholine Receptors in Native Membranes Studied by Dynamic Nuclear Polarization NMR

(2011) Arne H. Linden et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conformation of a Seven-Helical Transmembrane Photosensor in the Lipid Environment

(2010) Lichi Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fundamental functionality: recent developments in understanding the structure–activity relationships of lantibiotic peptides

(2010) Avena C Ross et al.   JOURNAL OF ANTIBIOTICS

Dynamic nuclear polarization-enhanced solid-state NMR spectroscopy of GNNQQNY nanocrystals and amyloid fibrils

(2010) Galia T. Debelouchina et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

(2010) T. Schneider et al.   SCIENCE

Low-power decoupling at high spinning frequencies in high static fields

(2009) Markus Weingarth et al.   JOURNAL OF MAGNETIC RESONANCE

Functional and shunt states of bacteriorhodopsin resolved by 250 GHz dynamic nuclear polarization-enhanced solid-state NMR

(2009) V. S. Bajaj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improved magnetization transfer in solid-state NMR with fast magic angle spinning

(2008) Markus Weingarth et al.   CHEMICAL PHYSICS LETTERS

The generation of nisin variants with enhanced activity against specific Gram-positive pathogens

(2008) Des Field et al.   MOLECULAR MICROBIOLOGY