Exploiting correlated molecular-dynamics networks to counteract enzyme activity–stability trade-off

Coupled molecular dynamics mediate long- and short-range epistasis between mutations that affect stability and aggregation kinetics

(2018) Haoran Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two strategies to engineer flexible loops for improved enzyme thermostability

(2017) Haoran Yu et al.   Scientific Reports

Defying the activity–stability trade-off in enzymes: taking advantage of entropy to enhance activity and thermostability

(2016) Khawar Sohail Siddiqui   CRITICAL REVIEWS IN BIOTECHNOLOGY

The RING 2.0 web server for high quality residue interaction networks

(2016) Damiano Piovesan et al.   NUCLEIC ACIDS RESEARCH

Balancing the Stability-Activity Trade-Off by Fine-Tuning Dehalogenase Access Tunnels

(2015) Veronika Liskova et al.   ChemCatChem

Engineering proteins for thermostability through rigidifying flexible sites

(2013) Haoran Yu et al.   BIOTECHNOLOGY ADVANCES

Mutational effects on stability are largely conserved during protein evolution

(2013) O. Ashenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strategy and success for the directed evolution of enzymes

(2011) Paul A Dalby   CURRENT OPINION IN STRUCTURAL BIOLOGY

Directed evolution of transketolase substrate specificity towards an aliphatic aldehyde

(2008) E HIBBERT et al.   JOURNAL OF BIOTECHNOLOGY