Targeted delivery of nitric oxide via a ‘bump-and-hole’-based enzyme–prodrug pair

Chemical hijacking of auxin signaling with an engineered auxin–TIR1 pair

(2018) Naoyuki Uchida et al.   Nature Chemical Biology

Antiinflammatory actions of inorganic nitrate stabilize the atherosclerotic plaque

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Enzyme Prodrug Therapy Engineered into Electrospun Fibers with Embedded Liposomes for Controlled, Localized Synthesis of Therapeutics

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Therapeutic assessment of mesenchymal stem cells delivered within a PEGylated fibrin gel following an ischemic injury

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The origin of renal fibroblasts/myofibroblasts and the signals that trigger fibrosis

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IGF-1 C Domain-Modified Hydrogel Enhances Cell Therapy for AKI

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Macrocyclic trichothecenes as antifungal and anticancer compounds

(2015) Maira de Carvalho et al.   CURRENT MEDICINAL CHEMISTRY

Enzyme-functionalized vascular grafts catalyze in-situ release of nitric oxide from exogenous NO prodrug

(2015) Zhihong Wang et al.   JOURNAL OF CONTROLLED RELEASE

New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain Inhibition

(2015) Matthias G. J. Baud et al.   JOURNAL OF MEDICINAL CHEMISTRY

Strategies to increase nitric oxide signalling in cardiovascular disease

(2015) Jon O. Lundberg et al.   NATURE REVIEWS DRUG DISCOVERY

HDL abnormalities in nephrotic syndrome and chronic kidney disease

(2015) Nosratola D. Vaziri   Nature Reviews Nephrology

A Nitric Oxide-Donor Furoxan Moiety Improves the Efficacy of Edaravone against Early Renal Dysfunction and Injury Evoked by Ischemia/Reperfusion

(2015) Fausto Chiazza et al.   Oxidative Medicine and Cellular Longevity

Blood Kidney Injury Molecule-1 Is a Biomarker of Acute and Chronic Kidney Injury and Predicts Progression to ESRD in Type I Diabetes

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A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes

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Polysaccharide-based biomaterials with on-demand nitric oxide releasing property regulated by enzyme catalysis

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Origin and function of myofibroblasts in kidney fibrosis

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Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation

(2013) K. Islam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

eNOS Deficiency Predisposes Podocytes to Injury in Diabetes

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Complexity in biomaterials for tissue engineering

(2009) Elsie S. Place et al.   NATURE MATERIALS

Nitric oxide and nanotechnology: A novel approach to inhibit neointimal hyperplasia

(2008) Muneera R. Kapadia et al.   JOURNAL OF VASCULAR SURGERY

A lifeline for suffocating tissues

(2008) Massimiliano Mazzone et al.   NATURE

The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics

(2008) Jon O. Lundberg et al.   NATURE REVIEWS DRUG DISCOVERY

Recent developments in nitric oxide donor drugs

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