PICK1 Deficiency Induces Autophagy Dysfunction via Lysosomal Impairment and Amplifies Sepsis-Induced Acute Lung Injury

Beclin-1-Dependent Autophagy Protects the Heart During Sepsis

(2018) Yuxiao Sun et al.   CIRCULATION

ROS-AKT-mTOR axis mediates autophagy of human umbilical vein endothelial cells induced by cooking oil fumes-derived fine particulate matters in vitro

(2017) Rui Ding et al.   FREE RADICAL BIOLOGY AND MEDICINE

Caspase-11–mediated endothelial pyroptosis underlies endotoxemia-induced lung injury

(2017) Kwong Tai Cheng et al.   JOURNAL OF CLINICAL INVESTIGATION

Atg7 Deficiency Intensifies Inflammasome Activation and Pyroptosis inPseudomonasSepsis

(2017) Qinqin Pu et al.   JOURNAL OF IMMUNOLOGY

Impaired lysosomal activity mediated autophagic flux disruption by graphite carbon nanofibers induce apoptosis in human lung epithelial cells through oxidative stress and energetic impairment

(2017) Sandeep Mittal et al.   Particle and Fibre Toxicology

MiR-155 Alleviates Septic Lung Injury by Inducing Autophagy Via Inhibition of Transforming Growth Factor-β-Activated Binding Protein 2

(2017) Fen Liu et al.   SHOCK

Heme Oxygenase-1/Carbon Monoxide-regulated Mitochondrial Dynamic Equilibrium Contributes to the Attenuation of Endotoxin-induced Acute Lung Injury in Rats and in Lipopolysaccharide-activated Macrophages

(2016) Jianbo Yu et al.   ANESTHESIOLOGY

SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages

(2016) Min-Ji Kim et al.   Autophagy

PICK1 confers anti-inflammatory effects in acute liver injury via suppressing M1 macrophage polarization

(2016) Juan Xie et al.   BIOCHIMIE

Sirt1 regulates acrosome biogenesis by modulating autophagic flux during spermiogenesis in mice

(2016) Chao Liu et al.   DEVELOPMENT

Autophagy in acute kidney injury

(2016) Gur P. Kaushal et al.   KIDNEY INTERNATIONAL

Acupuncture promotes mTOR-independent autophagic clearance of aggregation-prone proteins in mouse brain

(2016) Tian Tian et al.   Scientific Reports

mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1

(2016) Claudia Manzoni et al.   Scientific Reports

Redox regulation of mitophagy in the lung during murine Staphylococcus aureus sepsis

(2015) Alan L. Chang et al.   FREE RADICAL BIOLOGY AND MEDICINE

ICA1L forms BAR-domain complexes with PICK1 and is crucial for acrosome formation in spermiogenesis

(2015) J. He et al.   JOURNAL OF CELL SCIENCE

Protein Interacting with C-Kinase 1 Deficiency Impairs Glutathione Synthesis and Increases Oxidative Stress via Reduction of Surface Excitatory Amino Acid Carrier 1

(2015) Y.-N. Wang et al.   JOURNAL OF NEUROSCIENCE

Punicalagin Induces Nrf2/HO-1 Expression via Upregulation of PI3K/AKT Pathway and Inhibits LPS-Induced Oxidative Stress in RAW264.7 Macrophages

(2015) Xiaolong Xu et al.   MEDIATORS OF INFLAMMATION

Interaction of caveolin-1 with ATG12-ATG5 system suppresses autophagy in lung epithelial cells

(2014) Zhi-Hua Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cecal Ligation and Puncture-induced Sepsis as a Model To Study Autophagy in Mice

(2014) Ilias I. Siempos et al.   Jove-Journal of Visualized Experiments

C-Terminal Domain of ICA69 Interacts with PICK1 and Acts on Trafficking of PICK1-PKCα Complex and Cerebellar Plasticity

(2013) Zhen Wang et al.   PLoS One

Lc3 Over-Expression Improves Survival and Attenuates Lung Injury Through Increasing Autophagosomal Clearance in Septic Mice

(2012) Steven Lo et al.   ANNALS OF SURGERY

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB

(2012) Jose A. Martina et al.   Autophagy

PICK1 promotes caveolin-dependent degradation of TGF-β type I receptor

(2012) Bing Zhao et al.   CELL RESEARCH

Nationwide Trends of Severe Sepsis in the 21st Century (2000–2007)

(2011) Gagan Kumar et al.   CHEST

Inhibition of MTOR Disrupts Autophagic Flux in Podocytes

(2011) D. P. Cina et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest

(2011) Ian G. Ganley et al.   MOLECULAR CELL

Mechanisms of cellular adaptation to quantum dots – the role of glutathione and transcription factor EB

(2011) Kevin D. Neibert et al.   Nanotoxicology

Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation

(2011) Y. Rong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cecal ligation and puncture: the gold standard model for polymicrobial sepsis?

(2011) Lien Dejager et al.   TRENDS IN MICROBIOLOGY

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

PICK1 deficiency causes male infertility in mice by disrupting acrosome formation

(2009) Nan Xiao et al.   JOURNAL OF CLINICAL INVESTIGATION

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE

When apoptosis meets autophagy: deciding cell fate after trauma and sepsis

(2009) Ya-Ching Hsieh et al.   TRENDS IN MOLECULAR MEDICINE

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE