Article
Chemistry, Organic
Shan Mei, Qi Ou, Xingchen Tang, Jiang-Fei Xu, Xi Zhang
Summary: A host-guest strategy based on cucurbit[7]uril was used to enhance the efficiency of photolysis reactions, resulting in a 40-fold increase in the quantum yield. The stabilization of the contact ion pair by cucurbit[7]uril lowered the Gibbs free energy by 3.06 kcal/mol, as evidenced by DFT calculations. This research provides a novel strategy to improve reactions involving active cations, enriching the field of supramolecular catalysis.
Article
Chemistry, Multidisciplinary
Yawen Li, Qingfang Li, Xiaran Miao, Chunyan Qin, Dake Chu, Liping Cao
Summary: Achiral supramolecular organic framework (SOF-1) can exhibit adaptive chirality induced by specific compounds in water, leading to mirror-image circular dichroism and circularly polarized luminescence. This adaptive chirality can be utilized for determining the enantiopurity of amino acids and distinguishing biological chiral macromolecules.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Mantao Chen, Chi Hu, Shengxiang Zhang, Dan Wu, Zhengwei Mao, Xiujue Zheng
Summary: Two supramolecular nanomedicines based on the host-guest recognition between CB[7] and anticancer drugs were developed, improving the stability and solubility of the drugs while maintaining their anticancer activities.
FRONTIERS IN CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Sai Shradha Reddy Kommidi, Bradley D. Smith
Summary: Two new azobenzene heptamethine cyanine conjugates exhibit near-infrared (NIR) absorption and fluorescence properties, and the addition of cucurbit[7]uril (CB7) can induce dye deaggregation and significantly increase NIR fluorescence emission intensity. CB7 encapsulates the protonated azonium tautomer of the azobenzene component and produces a distinctive new absorption band. The hydrophilic nature of the complex suggests that CB7 can be used as a supramolecular additive to solubilize this new family of NIR azobenzene-cyanine conjugates for future biomedical applications.
Article
Chemistry, Multidisciplinary
Wenbing Cao, Xuewen Qin, Yong Wang, Zhen Dai, Xianyin Dai, Haoyu Wang, Weimin Xuan, Yingming Zhang, Yu Liu, Tao Liu
Summary: A general host-guest molecular recognition approach involving modification of protein functional surfaces with genetically encoded unnatural amino acids has been developed in this study, which can reversibly regulate protein function through molecular recognition, providing valuable tools for studying protein functions.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Z. -Y. Zhang, J. -F. Lv, L. Li, M. Dong, J. -J. Zhang, H. Cui, X. Tang, D. Guo, Y. Zhou, Y. -Y. Zhang, B. Ding, X. Wang, C. Li
Summary: In this study, an emission enhancement strategy was achieved by introducing phosphorescent antennas and complexing with cucurbit[7]uril (CB [7]). The resulting compounds showed strong near-infrared emission with quantum efficiencies as high as 6.6% in aerated water. Furthermore, complexing with CB [7] significantly enhanced their emission and improved quantum efficiency to a record value of 11.0% in aerated water by suppressing nonradiative decay of triplet state and improving intramolecular energy transfer. This result provides a general strategy for emission enhancement and is likely to promote the development of organic photoluminescence.
MATERIALS TODAY CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Andre Seco, Shilin Yu, Arnaud Tron, Nathan D. McClenaghan, Fernando Pina, A. Jorge Parola, Nuno Basilio
Summary: A linear double pyridinium-terminated thread with a central chalcone moiety provides two independent binding sites for cucurbit[7]uril macrocycles in water. The association leads to [2] and [3] pseudorotaxanes, which are pH and photosensitive, with enhanced association upon switching to the cationic flavylium form. Threading the flavylium moiety into CB7 results in a significant increase in fluorescence quantum yield.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Review
Chemistry, Multidisciplinary
Ying Huang, Rui-Han Gao, Ming Liu, Li-Xia Chen, Xin-Long Ni, Xin Xiao, Hang Cong, Qian-Jiang Zhu, Kai Chen, Zhu Tao
Summary: This review summarizes various QSFs assembled via OSIQs, which can be classified as being assembled by self-induced OSIQ, anion-induced OSIQ, and aromatic-induced OSIQ. The design and construction of QSFs with novel structures and specific functional properties may establish a new research direction in Q[n] chemistry.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Physical
Qin Wang, Jun-Zhuo Guo, Dan Luo, Ming-Fu Ye, Rui-Lian Lin, Wen-Qi Sun, Jing-Xin Liu
Summary: In the investigation of photochromic materials based on supramolecular host-guest systems, a unique viologen derivative without oxygen atoms was designed and synthesized, showing interesting fluorescence emission and reversible photochromism in the obtained supramolecular host-guest complex. Experimental data suggest the photochromic process is from electron transfer between the host and guest.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Chemistry, Inorganic & Nuclear
Masaomi Matsumoto, Jon Reid, Connor Byeman, Osasere Evbuomwan
Summary: This work reports the supramolecular complexation of an antenna-sensitized DOTAM-Eu complex with Cucurbit[7]uril (CB[7]), which was observed through UV-Vis and NMR spectroscopy. The inclusion of the antenna moiety in the CB[7] cavity enhances the Europium luminescence quantum yield. The photophysics of the analogous DOTAM-Gd complex was studied to understand the mechanism by which antenna-inclusion leads to the supramolecular luminescence enhancement. Additionally, supramolecular enhancement of Eu-ligand complex stability is also reported.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2022)
Article
Biotechnology & Applied Microbiology
Won-Bin Bae, Hee-Joon Kim, Kwang-Hwan Jhee
Summary: The study demonstrates the different supramolecular complexation behavior of homocysteine (Hcy) and cysteine (Cys) with cucurbit[7]uril (CB[7]) under basic pH conditions. Hcy efficiently forms a complex with CB[7] while Cys does not, highlighting a potential tool for quantifying Hcy concentration, a risk factor for cardiovascular disease.
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Zheng-Kun Bai, Qing-Mei Ge, Nan Jiang, Hang Cong, Yun-Qian Zhang, Mao Liu, Ying Fan
Summary: A ternary composite (CdS@PANI/Q[7]) consisting of CdS semiconductor, PANI, and Q[7] has been synthesized. This material exhibits high catalytic activity for the photocatalytic degradation of thiamethoxam under visible-light, achieving a removal efficiency of 85% with a kinetic constant of 0.003 min-1. The proposed catalytic mechanism involves the restrained recombination of photoinduced hole-electron pairs and enhanced contact between the photocatalyst and the thiamethoxam substrate.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Chemistry, Multidisciplinary
Yun Lu, Zhichao Yu, Xinan Yang, Jingjing Dai, Peihui Shan, Xianhao Feng, Zhu Tao, Carl Redshaw, Xin Xiao
Summary: The binding interactions between 4-aminopyridine (4-AP) and a series of cucurbit[n]urils (Q[5], Q[6], TMeQ[6], Q[7], Q[8]) were investigated using various techniques. The results showed that only the Q[5]@4-AP complex exhibited exo binding while the other hosts formed different types of complexes. X-ray crystallography provided detailed information on the binding modes of Q[n]s with 4-AP. The study revealed the importance of cavity size in determining the stability of the complexes. Overall, the research provides valuable insights into the binding properties of cucurbit[n]urils with 4-AP. (c) 2023 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Huaming Feng, Yang Luo, Ming Liu, Qing Chen, Zhu Tao, Xin Xiao
Summary: In this study, a porous supramolecular assembly (Q[8]-PSA) was prepared using Q[8] as the building block, forming a structure with uniform pore size, large specific surface area, suitable for drug adsorption and controlled release.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Physical
Zhi-Chao Yu, Yun Lu, Jie Zhao, Jing -Jing Dai, Guo-Rong Chen, Pei-Hui Shan, Carl Redshaw, Zhu Tao, Xin Xiao
Summary: The binding interaction between 4-cyanophenol (4-CY) and cucurbit[7]uril has been studied. The absorption and emission spectra obtained in aqueous solution revealed the formation of a 1:1 host-guest type complex. By introducing [ZnCl4]2- and Ca2+ as structural inducers, a single crystal structure was obtained, showing weak interactions between 4-CY and Q[7] or [ZnCl4]2-. The supramolecular framework based on Q[7] exhibited a Chinese knot-like structure.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Polymer Science
Jun Wang, Xin-Yue Lou, Jun Tang, Ying-Wei Yang
Summary: This study reports on the development of color-tunable room temperature phosphorescence (RTP) luminescent materials with stimuli-responsive properties. The extended red-shifted multicolor RTP afterglow from blue to orange, including white light, is achieved using a series of newly designed supramolecular polymers. The addition of pH-sensitive fragments enables a comprehensive blue-shifted color tuning range. The optimized intelligent multicolor RTP systems show great potential for practical applications.
JOURNAL OF POLYMER SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Tianze Zhang, Xin-Yue Lou, Xiaoyan Li, Xi Tu, Jie Han, Bin Zhao, Ying-Wei Yang
Summary: A series of spirooxazine derivatives (SO1-SO4) with bulky aromatic substituents have been designed and synthesized. They exhibit tunable solid photochromism without ground colors, excellent fatigue resistance, and high thermal stability. The ideal photochromic properties of these spirooxazines open a new avenue for their applications in UV printing, quick response code, and related fields.
ADVANCED MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Jia-Rui Wu, Gengxin Wu, Dongxia Li, Ying-Wei Yang
Summary: Synthetic macrocycles have played a significant role in supramolecular chemistry, expanding the scope of organic charge transfer complexes and demonstrating practical value in the solid state. This MiniReview summarizes the research progress on macrocycle-based crystalline supramolecular assemblies driven by intermolecular charge transfer interactions (MCCAs). The assemblies are classified based on their donor-acceptor constituent elements, including simplex macrocyclic hosts, heterogeneous macrocyclic hosts, and host-guest D-A pairs. The diverse functions, applications, and underlying charge transfer mechanisms are discussed from the perspective of crystal engineering. The remaining challenges and prospects are also outlined.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Polymer Science
You-Tao Xin, Lu-Yao Wang, Huan-Huan Chang, Fei-He Ma, Ming-Lei Sun, Li Chen, Hui Gao
Summary: A new dendrimer-based nanocomplex was developed by conjugating Pt(IV)-complex and lauric acid (LA) to the dendritic carrier PAMAM (G=3), and further coated with hyaluronic acid (HA) on its surface to enhance biocompatibility and tumor targeting. The nanocomplex demonstrated good biocompatibility, high anti-colorectal cancer activity and high anti-Fn activity.
CHINESE JOURNAL OF POLYMER SCIENCE
(2023)
Article
Polymer Science
Yong-Fu Li, Wen-Li Guan, Chun-Yu Wang, Yan Wang, Qi Lin, Ying-Wei Yang
Summary: A metallosupramolecular polymer network (DSPy subset of SHP5@Zn) was constructed by hierarchical self-assembly of a double-armed pillar[5]arene host (SHP5), a ditopic guest (DSPy), and Zn2+ ions, with host-guest recognition and metal-ligand coordination interactions playing a crucial role. The DSPy subset of SHP5@Zn assembly exhibits reversible sol-gel transition properties in response to various external stimuli, making it an excellent candidate for constructing smart gels. In addition, it can be used as a highly selective dual-channel sensor for OH anions, facilitating the development of a convenient test kit for OH sensing.
Review
Chemistry, Multidisciplinary
Zhuo-Qin Wang, Xin Wang, Ying-Wei Yang
Summary: The design and synthesis of supramolecular polymers based on pillararenes have advanced the fields of supramolecular chemistry and polymer science. This review summarizes recent progress in the design, synthesis, and applications of pillararene-based supramolecular polymers (PSPs) as adsorption and separation materials. The review discusses the performance evaluation, topology classification, and challenges in functional supramolecular polymeric adsorbents. The future perspectives of PSPs for separation-based materials science are also explored.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Xin-Yue Lou, Ge Zhang, Meng-Hao Li, Ying-Wei Yang
Summary: In this study, a novel type of macrocycle-strutted coordination microparticle (MSCM) was constructed using pillararenes as the struts and pockets, which exhibited unique activities of fluorescence-monitored photosensitization and substrate-selective photocatalytic degradation. The MSCMs were prepared via a one-step solvothermal method and showed well-ordered spherical architectures, superior photo-physical properties, and photosensitizing capacity. The photo-catalytic behaviors of the MSCMs revealed marked substrate-selective catalytic mechanisms, attributed to the variety in the affinity of substrates toward MSCM surfaces and pillararene cavities.
Review
Engineering, Biomedical
Siyuan Zhang, Xin-Yue Lou, Linlin Liu, Ying-Wei Yang
Summary: DNA origami technology, a unique type of DNA nanotechnology, has attracted much attention from researchers and is applied in various fields. DNA origami nanostructures are endowed with excellent programmability and addressability and show outstanding biocompatibility in bio-related applications, especially in cancer treatment.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Shuzhen Yan, Xinlu Deng, Shuai Chen, Tianjiao Ma, Tiantian Li, Kaiming Hu, Xuesong Jiang
Summary: This study demonstrates a facile method for fabricating surface patterns on polyurethane elastomer by utilizing the Poisson effect and gradient photocrosslinking. The aspect ratio of the patterns can be manipulated by uniaxial tensile strains. The macromolecular aggregation structures and controlled internal stress contribute to the fabrication of high aspect ratio patterns. The patterns exhibit tunable structural color and are fully reversible.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Meng-Hao Li, Zhiqiang Yang, Hui Hui, Bing Yang, Yan Wang, Ying-Wei Yang
Summary: Hierarchical assemblies with diverse properties are fabricated using covalent organic frameworks (COFs) and metal-organic frameworks (MOFs) as building blocks, resulting in highly active photocatalytic systems. The multilayered structural states within the supramolecular systems demonstrate the importance of hierarchical assemblies in facilitating photocatalytic propagation and expanding the structural repertoire of supramolecular hybrids.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Xin Xiao, Zheng Li, Ying Xiong, Ying-Wei Yang
Summary: An effective porous carbon matrix derived from cucurbit[6]uril was used to support iridium-molybdenum (IrMo) nanoclusters, resulting in an IrMo-doped carbon electrocatalyst (IrMo-CBC) with significantly improved alkaline hydrogen evolution reaction (HER) activity. IrMo-CBC exhibited an extremely low overpotential of 12 mV, an ultrasmall Tafel slope of 28.06 mV dec(-1), a superior faradic efficiency of 98%, and a high turnover frequency (TOF) of 11.6 H-2 s(-1) at an overpotential of 50 mV, outperforming most iridium-based electrocatalysts and commercial Pt/C.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Review
Chemistry, Multidisciplinary
Zheng Li, Weiwei Huan, Yan Wang, Ying-Wei Yang
Summary: Discrete organometallic complexes with defined structures have shown promising applications in the treatment of malignant tumors. Their advantages, including high antitumor activity, low toxicity, active targeting ability, and enhanced cellular uptake, make them suitable for clinical use. In particular, coordination-induced regulation of luminescence and photophysical properties has potential in evaluating therapeutic efficacy and enabling synergistic photodynamic or photothermal therapy. This review focuses on multimodal radiochemotherapy platforms based on self-assembled metallacycles/metallacages for cancer ablation, classifying them according to their functions. The review also discusses the demands and prospects for future development in this field.
Article
Multidisciplinary Sciences
Jia-Rui Wu, Gengxin Wu, Dongxia Li, Meng-Hao Li, Yan Wang, Ying-Wei Yang
Summary: In this study, a switchable vapochromic system for bromoalkane isomers was developed using charge-transfer complexes in the solid state, demonstrating a simple colorimetric method for distinguishing positional isomers.
NATURE COMMUNICATIONS
(2023)
Review
Chemistry, Multidisciplinary
Xin Li, Jie Yang, Ying-Wei Yang
Summary: This article summarizes the research progress of viologen-based nanocomposites, which include viologen-based metal-organic frameworks, covalent organic frameworks, and supramolecular assemblies, for exploring and promoting more applications of smart materials in practical production. These unique electron-deficient viologen-based compounds exhibit excellent photoelectric response features, and when combined with porous frameworks and supramolecular assemblies, show great application prospects in discolouration sensing, catalysis, energy storage, and biomedicine. By employing viologen-based compounds as stimuli-responsive units to coordinate with various bonding types, the newly formed nanocomposites can effectively enhance the stimuli-responsive performance of materials.
MATERIALS CHEMISTRY FRONTIERS
(2023)
Review
Chemistry, Multidisciplinary
Xin-Yue Lou, Siyuan Zhang, Yan Wang, Ying-Wei Yang
Summary: Innovative design of smart organic materials is of great importance for the advancement of modern technology. Macrocycle hosts, possessing cyclic skeletons, intrinsic cavities, and specific guest binding properties, have demonstrated pronounced potential for the elaborate fabrication of a variety of functional organic materials with smart stimuli-responsive characteristics.
CHEMICAL SOCIETY REVIEWS
(2023)
