Integration of Precipitation Kinetics From an In Vitro, Multicompartment Transfer System and Mechanistic Oral Absorption Modeling for Pharmacokinetic Prediction of Weakly Basic Drugs

标题
Integration of Precipitation Kinetics From an In Vitro, Multicompartment Transfer System and Mechanistic Oral Absorption Modeling for Pharmacokinetic Prediction of Weakly Basic Drugs
作者
关键词
dissolution, dissolution model(s), in vitro, model(s), precipitation, bioavailability, oral absorption, pharmacokinetics, GastroPlus modeling, solubility, simulation(s)
出版物
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 108, Issue 1, Pages 574-583
出版商
Elsevier BV
发表日期
2018-11-03
DOI
10.1016/j.xphs.2018.10.051

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