Hif-1α–Induced Expression of Il-1β Protects against Mycobacterial Infection in Zebrafish

Phenolic Glycolipid Facilitates Mycobacterial Escape from Microbicidal Tissue-Resident Macrophages

(2017) C.J. Cambier et al.   IMMUNITY

Inflammasome activation and assembly at a glance

(2017) Ankit Malik et al.   JOURNAL OF CELL SCIENCE

Efferocytosis and extrusion of leukocytes determine the progression of early mycobacterial pathogenesis

(2016) Rohola Hosseini et al.   JOURNAL OF CELL SCIENCE

HIF-1α Is an Essential Mediator of IFN-γ–Dependent Immunity toMycobacterium tuberculosis

(2016) Jonathan Braverman et al.   JOURNAL OF IMMUNOLOGY

Cryptococcus neoformans Intracellular Proliferation and Capsule Size Determines Early Macrophage Control of Infection

(2016) Aleksandra Bojarczuk et al.   Scientific Reports

The innate immune response in human tuberculosis

(2015) Thomas R. Lerner et al.   CELLULAR MICROBIOLOGY

Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models

(2015) P. M. Elks et al.   Disease Models & Mechanisms

Versatile myeloid cell subsets contribute to tuberculosis-associated inflammation

(2015) Anca Dorhoi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T cells and adaptive immunity toMycobacterium tuberculosisin humans

(2015) Luke D. Jasenosky et al.   IMMUNOLOGICAL REVIEWS

Epigenetic control of intestinal barrier function and inflammation in zebrafish

(2015) Lindsay Marjoram et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protection and pathology in TB: learning from the zebrafish model

(2015) Annemarie H. Meijer   Seminars in Immunopathology

Identification of polarized macrophage subsets in zebrafish

(2015) Mai Nguyen-Chi et al.   eLife

The DNA Damage-Regulated Autophagy Modulator DRAM1 Links Mycobacterial Recognition via TLR-MYD88 to Autophagic Defense

(2014) Michiel van der Vaart et al.   Cell Host & Microbe

The TLR and IL-1 signalling network at a glance

(2014) P. Cohen   JOURNAL OF CELL SCIENCE

Interaction of Pattern Recognition Receptors with Mycobacterium Tuberculosis

(2014) Esmaeil Mortaz et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Mycobacteria Counteract a TLR-Mediated Nitrosative Defense Mechanism in a Zebrafish Infection Model

(2014) Philip M. Elks et al.   PLoS One

Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish

(2013) A. Hruscha et al.   DEVELOPMENT

Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system

(2013) M. van der Vaart et al.   Disease Models & Mechanisms

Zebrafish tissue injury causes upregulation of interleukin-1 and caspase-dependent amplification of the inflammatory response

(2013) N. V. Ogryzko et al.   Disease Models & Mechanisms

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids

(2013) C. J. Cambier et al.   NATURE

Macrophages in tuberculosis: friend or foe

(2013) Evelyn Guirado et al.   Seminars in Immunopathology

Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism

(2013) Philip M. Elks et al.   PLoS Pathogens

A Zebrafish Model to Study and Therapeutically Manipulate Hypoxia Signaling in Tumorigenesis

(2012) Kirankumar Santhakumar et al.   CANCER RESEARCH

Infection of macrophages withMycobacterium tuberculosisinduces global modifications to phagosomal function

(2012) Maria Podinovskaia et al.   CELLULAR MICROBIOLOGY

Activation of hypoxia-inducible factor-1  (Hif-1 ) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model

(2011) P. M. Elks et al.   BLOOD

Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component

(2011) E. J. M. Stoop et al.   Disease Models & Mechanisms

Microbial Colonization Induces Dynamic Temporal and Spatial Patterns of NF-κB Activation in the Zebrafish Digestive Tract

(2011) Michelle Kanther et al.   GASTROENTEROLOGY

Mycobacterium tuberculosis Triggers Host Type I IFN Signaling To Regulate IL-1  Production in Human Macrophages

(2011) A. Novikov et al.   JOURNAL OF IMMUNOLOGY

Evolutionary conserved pro-inflammatory and antigen presentation functions of zebrafish IFNγ revealed by transcriptomic and functional analysis

(2011) Azucena López-Muñoz et al.   MOLECULAR IMMUNOLOGY

Pharmacological Characterization of 1-(5-Chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic Acid (JNJ-42041935), a Potent and Selective Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor

(2011) T. D. Barrett et al.   MOLECULAR PHARMACOLOGY

Macrophages and control of granulomatous inflammation in tuberculosis

(2011) J L Flynn et al.   Mucosal Immunology

The challenge of new drug discovery for tuberculosis

(2011) Anil Koul et al.   NATURE

Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components

(2009) Astrid M. van der Sar et al.   MOLECULAR IMMUNOLOGY

Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

(2008) L. E. Via et al.   INFECTION AND IMMUNITY

Interleukin‐12 and Interleukin‐27 Regulate Macrophage Control ofMycobacterium tuberculosis

(2008) Cory M. Robinson et al.   JOURNAL OF INFECTIOUS DISEASES