Zebrafish NDRG1a Negatively Regulates IFN Induction by Promoting the Degradation of IRF7

Zebrafish IRF1, IRF3, and IRF7 Differentially Regulate IFNΦ1 and IFNΦ3 Expression through Assembly of Homo- or Heteroprotein Complexes

(2016) Hui Feng et al.   JOURNAL OF IMMUNOLOGY

Spring Viremia of Carp Virus N Protein Suppresses Fish IFNφ1 Production by Targeting the Mitochondrial Antiviral Signaling Protein

(2016) Long-Feng Lu et al.   JOURNAL OF IMMUNOLOGY

The P Protein of Spring Viremia of Carp Virus Negatively Regulates the Fish Interferon Response by Inhibiting the Kinase Activity of TANK-Binding Kinase 1

(2016) Shun Li et al.   JOURNAL OF VIROLOGY

Functions of the two zebrafish MAVS variants are opposite in the induction of IFN1 by targeting IRF7

(2015) Long-Feng Lu et al.   FISH & SHELLFISH IMMUNOLOGY

IFN Regulatory Factor 10 Is a Negative Regulator of the IFN Responses in Fish

(2014) S. Li et al.   JOURNAL OF IMMUNOLOGY

Lysine 63-Linked TANK-Binding Kinase 1 Ubiquitination by Mindbomb E3 Ubiquitin Protein Ligase 2 Is Mediated by the Mitochondrial Antiviral Signaling Protein

(2014) J. S. Ye et al.   JOURNAL OF VIROLOGY

Metastasis suppressor, NDRG1, mediates its activity through signaling pathways and molecular motors

(2013) J. Sun et al.   CARCINOGENESIS

Negative Regulation of Nmi on Virus-Triggered Type I IFN Production by Targeting IRF7

(2013) J. Wang et al.   JOURNAL OF IMMUNOLOGY

The Antiviral Innate Immune Response in Fish: Evolution and Conservation of the IFN System

(2013) Christelle Langevin et al.   JOURNAL OF MOLECULAR BIOLOGY

OASL1 inhibits translation of the type I interferon–regulating transcription factor IRF7

(2013) Myeong Sup Lee et al.   NATURE IMMUNOLOGY

Molecular regulation of interferon antiviral response in fish

(2012) Yi-Bing Zhang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

A FOXO3–IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses

(2012) Vladimir Litvak et al.   NATURE

Both STING and MAVS Fish Orthologs Contribute to the Induction of Interferon Mediated by RIG-I

(2012) Stéphane Biacchesi et al.   PLoS One

STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway

(2012) Y. Tanaka et al.   Science Signaling

The yin and yang of viruses and interferons

(2012) Ben X. Wang et al.   TRENDS IN IMMUNOLOGY

Teleost fish interferons and their role in immunity

(2011) Jun Zou et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

IRF7: activation, regulation, modification and function

(2011) S Ning et al.   GENES AND IMMUNITY

Recognition of nucleic acids by pattern-recognition receptors and its relevance in autoimmunity

(2011) Takumi Kawasaki et al.   IMMUNOLOGICAL REVIEWS

Guanylate Binding Protein 4 Negatively Regulates Virus-Induced Type I IFN and Antiviral Response by Targeting IFN Regulatory Factor 7

(2011) Y. Hu et al.   JOURNAL OF IMMUNOLOGY

Fish MITA Serves as a Mediator for Distinct Fish IFN Gene Activation Dependent on IRF3 or IRF7

(2011) F. Sun et al.   JOURNAL OF IMMUNOLOGY

Expression and Functional Characterization of the RIG-I-Like Receptors MDA5 and LGP2 in Rainbow Trout (Oncorhynchus mykiss)

(2011) M. Chang et al.   JOURNAL OF VIROLOGY

Viperin, a key player in the antiviral response

(2011) Sandy Mattijssen et al.   MICROBES AND INFECTION

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Characteristics of the interferon regulatory factor pairs zfIRF5/7 and their stimulation expression by ISKNV Infection in zebrafish (Danio rerio)

(2010) Zhiming Xiang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The N-myc downstream regulated gene (NDRG) family: diverse functions, multiple applications

(2010) Veerle Melotte et al.   FASEB JOURNAL

The Ubiquitin E3 Ligase RAUL Negatively Regulates Type I Interferon through Ubiquitination of the Transcription Factors IRF7 and IRF3

(2010) Yanxing Yu et al.   IMMUNITY

The Ubiquitin Ligase RNF5 Regulates Antiviral Responses by Mediating Degradation of the Adaptor Protein MITA

(2009) Bo Zhong et al.   IMMUNITY

New Insights into the Evolution of IFNs: Zebrafish Group II IFNs Induce a Rapid and Transient Expression of IFN-Dependent Genes and Display Powerful Antiviral Activities

(2009) A. Lopez-Munoz et al.   JOURNAL OF IMMUNOLOGY

Mitochondrial Antiviral Signaling Protein Plays a Major Role in Induction of the Fish Innate Immune Response against RNA and DNA Viruses

(2009) S. Biacchesi et al.   JOURNAL OF VIROLOGY

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

(2009) W. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The iron-regulated metastasis suppressor, Ndrg-1: Identification of novel molecular targets

(2008) Zaklina Kovacevic et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Negative regulation of cytoplasmic RNA-mediated antiviral signaling

(2008) Akihiko Komuro et al.   CYTOKINE

The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

(2008) Bo Zhong et al.   IMMUNITY

Negative Regulation of Virus-triggered IFN-β Signaling Pathway by Alternative Splicing of TBK1

(2008) Weiwen Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRAF6 and the Three C-Terminal Lysine Sites on IRF7 Are Required for Its Ubiquitination-Mediated Activation by the Tumor Necrosis Factor Receptor Family Member Latent Membrane Protein 1

(2008) S. Ning et al.   MOLECULAR AND CELLULAR BIOLOGY

MPYS, a Novel Membrane Tetraspanner, Is Associated with Major Histocompatibility Complex Class II and Mediates Transduction of Apoptotic Signals

(2008) L. Jin et al.   MOLECULAR AND CELLULAR BIOLOGY

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE

Evolution of MDA-5/RIG-I-dependent innate immunity: Independent evolution by domain grafting

(2008) D. Sarkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential regulation of IKKα-mediated activation of IRF3/7 by NIK

(2007) Rui-Peng Wang et al.   MOLECULAR IMMUNOLOGY