SR Ca2+ leak in skeletal muscle fibers acts as an intracellular signal to increase fatigue resistance

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Leaky ryanodine receptors contribute to diaphragmatic weakness during mechanical ventilation

(2016) Stefan Matecki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of PGC-1α during acute exercise-induced autophagy and mitophagy in skeletal muscle

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Excess TGF-β mediates muscle weakness associated with bone metastases in mice

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Ryanodine receptor fragmentation and sarcoplasmic reticulum Ca2+leak after one session of high-intensity interval exercise

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Altered Ca2+ Kinetics Associated with α-Actinin-3 Deficiency May Explain Positive Selection for ACTN3 Null Allele in Human Evolution

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Myocyte enhancer factor 2C function in skeletal muscle is required for normal growth and glucose metabolism in mice

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Creb coactivators direct anabolic responses and enhance performance of skeletal muscle

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Ligands for FKBP12 Increase Ca2+Influx and Protein Synthesis to Improve Skeletal Muscle Function

(2014) Chang Seok Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of a mammalian ryanodine receptor

(2014) Ran Zalk et al.   NATURE

FK506 binding proteins: Cellular regulators of intracellular Ca2+ signalling

(2013) Debbi MacMillan   EUROPEAN JOURNAL OF PHARMACOLOGY

Orai1-dependent calcium entry promotes skeletal muscle growth and limits fatigue

(2013) Lan Wei-LaPierre et al.   Nature Communications

Studies of Mitochondrial and Nonmitochondrial Sources Implicate Nicotinamide Adenine Dinucleotide Phosphate Oxidase(s) in the Increased Skeletal Muscle Superoxide Generation That Occurs During Contractile Activity

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AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation

(2012) Johanna T Lanner et al.   NATURE MEDICINE

Activation of calcium signaling through Trpv1 by nNOS and peroxynitrite as a key trigger of skeletal muscle hypertrophy

(2012) Naoki Ito et al.   NATURE MEDICINE

A new submaximal cycle ergometer test for prediction of VO2max

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Ryanodine Receptor Oxidation Causes Intracellular Calcium Leak and Muscle Weakness in Aging

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The role ofin vivoCa2+signals acting on Ca2+-calmodulin-dependent proteins for skeletal muscle plasticity

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Increased fatigue resistance linked to Ca2+-stimulated mitochondrial biogenesis in muscle fibres of cold-acclimated mice

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Repeated transient mRNA bursts precede increases in transcriptional and mitochondrial proteins during training in human skeletal muscle

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The cell boundary theorem: a simple law of the control of cytosolic calcium concentration

(2009) Eduardo Ríos   Journal of Physiological Sciences

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle

(2009) Andrew M Bellinger et al.   NATURE MEDICINE

Nonshivering thermogenesis protects against defective calcium handling in muscle

(2008) Jan Aydin et al.   FASEB JOURNAL

Skeletal Muscle Fatigue: Cellular Mechanisms

(2008) D. G. Allen et al.   PHYSIOLOGICAL REVIEWS

Remodeling of ryanodine receptor complex causes "leaky" channels: A molecular mechanism for decreased exercise capacity

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(2007) Benjamin D. Levine   JOURNAL OF PHYSIOLOGY-LONDON