Electrical coupling and its channels

Disruption of the lens circulation causes calcium accumulation and precipitates in connexin mutant mice

(2018) Junyuan Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Human diseases associated with connexin mutations

(2018) Miduturu Srinivas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Gating of Connexin Channels by transjunctional-voltage: Conformations and models of open and closed states

(2018) Thaddeus A. Bargiello et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels

(2018) Isaac E. García et al.   JOURNAL OF GENERAL PHYSIOLOGY

Connexins and Disease

(2017) Mario Delmar et al.   Cold Spring Harbor Perspectives in Biology

Functional asymmetry and plasticity of electrical synapses interconnecting neurons through a 36-state model of gap junction channel gating

(2017) Mindaugas Snipas et al.   PLoS Computational Biology

Calcium binding and voltage gating in Cx46 hemichannels

(2017) Bernardo I. Pinto et al.   Scientific Reports

Computational Studies of Molecular Permeation through Connexin26 Channels

(2016) Yun Luo et al.   BIOPHYSICAL JOURNAL

Stochastic Model of Gap Junctions Exhibiting Rectification and Multiple Closed States of Slow Gates

(2016) Mindaugas Snipas et al.   BIOPHYSICAL JOURNAL

Connexinopathies: a structural and functional glimpse

(2016) Isaac E. García et al.   BMC CELL BIOLOGY

Syndromic deafness mutations at Asn 14 differentially alter the open stability of Cx26 hemichannels

(2016) Helmuth A. Sanchez et al.   JOURNAL OF GENERAL PHYSIOLOGY

Reverberation of excitation in neuronal networks interconnected through voltage-gated gap junction channels

(2016) Kestutis Maciunas et al.   JOURNAL OF GENERAL PHYSIOLOGY

Mechanism of gating by calcium in connexin hemichannels

(2016) William Lopez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An electrostatic mechanism for Ca2+-mediated regulation of gap junction channels

(2016) Brad C. Bennett et al.   Nature Communications

Feedback Regulation of Intracellular Hydrostatic Pressure in Surface Cells of the Lens

(2015) Junyuan Gao et al.   BIOPHYSICAL JOURNAL

Glutathione release through connexin hemichannels: Implications for chemical modification of pores permeable to large molecules

(2015) Xuhui Tong et al.   JOURNAL OF GENERAL PHYSIOLOGY

Altered conductance and permeability of Cx40 mutations associated with atrial fibrillation

(2015) Ana Santa Cruz et al.   JOURNAL OF GENERAL PHYSIOLOGY

Mechanisms of cardiac conduction: a history of revisions

(2014) Rengasayee Veeraraghavan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Specific Cx43 phosphorylation events regulate gap junction turnover in vivo

(2014) Joell L. Solan et al.   FEBS LETTERS

Motifs in the permeation pathway of connexin channels mediate voltage and Ca2+ sensing

(2014) Andrew L. Harris et al.   Frontiers in Physiology

Divalent regulation and intersubunit interactions of human Connexin26 (Cx26) hemichannels

(2013) William Lopez et al.   Channels

Voltage-dependent gating of the Cx32*43E1 hemichannel: Conformational changes at the channel entrances

(2013) Taekyung Kwon et al.   JOURNAL OF GENERAL PHYSIOLOGY

Insights on the mechanisms of Ca2+regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y)

(2013) William Lopez et al.   JOURNAL OF GENERAL PHYSIOLOGY

The D50N mutation and syndromic deafness: Altered Cx26 hemichannel properties caused by effects on the pore and intersubunit interactions

(2013) Helmuth A. Sanchez et al.   JOURNAL OF GENERAL PHYSIOLOGY

Molecular Dynamics Simulations of the Cx26 Hemichannel: Insights into Voltage-Dependent Loop-Gating

(2012) Taekyung Kwon et al.   BIOPHYSICAL JOURNAL

Lens intracellular hydrostatic pressure is generated by the circulation of sodium and modulated by gap junction coupling

(2011) Junyuan Gao et al.   JOURNAL OF GENERAL PHYSIOLOGY

Mechanism of inhibition of connexin channels by the quinine derivativeN-benzylquininium

(2011) Clio Rubinos et al.   JOURNAL OF GENERAL PHYSIOLOGY

Mechanism for modulation of gating of connexin26-containing channels by taurine

(2011) Darren Locke et al.   JOURNAL OF GENERAL PHYSIOLOGY

Molecular dynamics simulations of the Cx26 hemichannel: Evaluation of structural models with Brownian dynamics

(2011) Taekyung Kwon et al.   JOURNAL OF GENERAL PHYSIOLOGY

Post-translational modifications of connexin26 revealed by mass spectrometry

(2009) Darren Locke et al.   BIOCHEMICAL JOURNAL

A Stochastic Four-State Model of Contingent Gating of Gap Junction Channels Containing Two “Fast” Gates Sensitive to Transjunctional Voltage

(2009) Nerijus Paulauskas et al.   BIOPHYSICAL JOURNAL

Conformational changes in a pore-forming region underlie voltage-dependent “loop gating” of an unapposed connexin hemichannel

(2009) Qingxiu Tang et al.   JOURNAL OF GENERAL PHYSIOLOGY

Functional differences between human Cx37 polymorphic hemichannels

(2009) Jean-Paul Derouette et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Structure of the connexin 26 gap junction channel at 3.5 Å resolution

(2009) Shoji Maeda et al.   NATURE

Loop Gating of Connexin Hemichannels Involves Movement of Pore-lining Residues in the First Extracellular Loop Domain

(2008) Vytas K. Verselis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Divalent Cations Regulate Connexin Hemichannels by Modulating Intrinsic Voltage-dependent Gating

(2008) Vytas K. Verselis et al.   JOURNAL OF GENERAL PHYSIOLOGY

Gap Junction Channels Exhibit Connexin-specific Permeability to Cyclic Nucleotides

(2008) Giedrius Kanaporis et al.   JOURNAL OF GENERAL PHYSIOLOGY