Inducible down-regulation of MHC class I results in natural killer cell tolerance

First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation

(2018) Rizwan Romee et al.   BLOOD

Next generation natural killer cells for cancer immunotherapy: the promise of genetic engineering

(2018) May Daher et al.   CURRENT OPINION IN IMMUNOLOGY

Immunoreceptor tyrosine-based inhibitory motif–dependent functions of an MHC class I-specific NK cell receptor

(2017) Michael D. Bern et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Checkpoint Inhibition of KIR2D with the Monoclonal Antibody IPH2101 Induces Contraction and Hyporesponsiveness of NK Cells in Patients with Myeloma

(2016) M. Carlsten et al.   CLINICAL CANCER RESEARCH

Differential Role of Hematopoietic and Nonhematopoietic Cell Types in the Regulation of NK Cell Tolerance and Responsiveness

(2016) Nataliya Tovbis Shifrin et al.   JOURNAL OF IMMUNOLOGY

IL-15 Superagonist–Mediated Immunotoxicity: Role of NK Cells and IFN-γ

(2015) Yin Guo et al.   JOURNAL OF IMMUNOLOGY

Dual Requirement of Cytokine and Activation Receptor Triggering for Cytotoxic Control of Murine Cytomegalovirus by NK Cells

(2015) Bijal A. Parikh et al.   PLoS Pathogens

A phase II trial of pan-KIR2D blockade with IPH2101 in smoldering multiple myeloma

(2014) N. Korde et al.   HAEMATOLOGICA

Cytokine therapy reverses NK cell anergy in MHC-deficient tumors

(2014) Michele Ardolino et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Viral Infection Breaks NK Cell Tolerance to "Missing Self"

(2014) J. C. Sun et al.   JOURNAL OF IMMUNOLOGY

Controlling Natural Killer Cell Responses: Integration of Signals for Activation and Inhibition

(2013) Eric O. Long et al.   Annual Review of Immunology

Natural killer cell licensing in mice with inducible expression of MHC class I

(2013) T. Ebihara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tolerance and exhaustion: defining mechanisms of T cell dysfunction

(2013) Andrea Schietinger et al.   TRENDS IN IMMUNOLOGY

Generation of CD4CreERT2transgenic mice to study development of peripheral CD4-T-cells

(2012) Katayoun Aghajani et al.   GENESIS

T-Cell Tolerance: Central and Peripheral

(2012) Y. Xing et al.   Cold Spring Harbor Perspectives in Biology

Natural killer cells act as rheostats modulating antiviral T cells

(2011) Stephen N. Waggoner et al.   NATURE

Natural Killer Cell Education and Tolerance

(2010) Mark T. Orr et al.   CELL

Mature natural killer cells reset their responsiveness when exposed to an altered MHC environment

(2010) Nathalie T. Joncker et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MHC class I–deficient natural killer cells acquire a licensed phenotype after transfer into an MHC class I–sufficient environment

(2010) Julie M. Elliott et al.   JOURNAL OF EXPERIMENTAL MEDICINE

In vivotumor cell rejection induced by NK cell inhibitory receptor blockade: Maintained tolerance to normal cells even in the presence of IL-2

(2009) Gustaf Vahlne et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells

(2009) Stephen McCartney et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Stability of Murine Cytomegalovirus Genome after In Vitro and In Vivo Passage

(2009) T. P. Cheng et al.   JOURNAL OF VIROLOGY