Novel Blood Biomarkers that Correlate with Cognitive Performance and Hippocampal Volumetry: Potential for Early Diagnosis of Alzheimer’s Disease

Increased Plasma Beta-Secretase 1 May Predict Conversion to Alzheimer’s Disease Dementia in Individuals With Mild Cognitive Impairment

(2018) Yong Shen et al.   BIOLOGICAL PSYCHIATRY

Metabolomic Signatures in Peripheral Blood Associated with Alzheimer's Disease Amyloid-β-Induced Neuroinflammation

(2018) Eosu Kim et al.   JOURNAL OF ALZHEIMERS DISEASE

Genome-Wide Serum microRNA Expression Profiling Identifies Serum Biomarkers for Alzheimer's Disease

(2018) Lin Tan et al.   JOURNAL OF ALZHEIMERS DISEASE

Spreading of Amyloid, Tau, and Microvascular Pathology in Alzheimer's Disease: Findings from Neuropathological and Neuroimaging Studies

(2018) Dietmar Rudolf Thal et al.   JOURNAL OF ALZHEIMERS DISEASE

Amino Acid Catabolism in Alzheimer’s Disease Brain: Friend or Foe?

(2017) Jeddidiah W. D. Griffin et al.   Oxidative Medicine and Cellular Longevity

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

(2017) Piotr Lewczuk et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

The impact of ageing reveals distinct roles for human dentate gyrus and CA3 in pattern separation and object recognition memory

(2017) Serena E. Dillon et al.   Scientific Reports

Branched-chain amino acids and Alzheimer’s disease: a Mendelian randomization analysis

(2017) Susanna C. Larsson et al.   Scientific Reports

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis

(2016) Luca A. Lotta et al.   PLOS MEDICINE

First effects of rising amyloid-β in transgenic mouse brain: synaptic transmission and gene expression

(2015) Damian M. Cummings et al.   BRAIN

Amyloid-β as a biomarker for Alzheimer’s disease: quantification methods in body fluids

(2015) Sara Galozzi et al.   Expert Review of Proteomics

Hypervalinemia and hyperleucine-isoleucinemia caused by mutations in the branched-chain-amino-acid aminotransferase gene

(2015) X. L. Wang et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Plasma proteins predict conversion to dementia from prodromal disease

(2014) Abdul Hye et al.   Alzheimers & Dementia

Quantitative Analysis of Amyloid Deposition in Alzheimer Disease Using PET and the Radiotracer 11C-AZD2184

(2014) H. Ito et al.   JOURNAL OF NUCLEAR MEDICINE

18F-FDG PET and Perfusion SPECT in the Diagnosis of Alzheimer and Lewy Body Dementias

(2014) J. T. O'Brien et al.   JOURNAL OF NUCLEAR MEDICINE

Plasma phospholipids identify antecedent memory impairment in older adults

(2014) Mark Mapstone et al.   NATURE MEDICINE

Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease

(2014) Kirsten L. Viola et al.   Nature Nanotechnology

Prognostic classification of mild cognitive impairment and Alzheimer׳s disease: MRI independent component analysis

(2014) Auriel A. Willette et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Glutamine synthetase in astrocytes from entorhinal cortex of the triple transgenic animal model of Alzheimer’s disease is not affected by pathological progression

(2013) Chia-Yu Yeh et al.   BIOGERONTOLOGY

Progress Update: Fluid and Imaging Biomarkers in Alzheimer’s Disease

(2013) Courtney L. Sutphen et al.   BIOLOGICAL PSYCHIATRY

Human Mild Traumatic Brain Injury Decreases Circulating Branched-Chain Amino Acids and Their Metabolite Levels

(2013) Cameron B. Jeter et al.   JOURNAL OF NEUROTRAUMA

GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease

(2013) Carlos Cruchaga et al.   NEURON

Branched-chain amino acid supplementation: impact on signaling and relevance to critical illness

(2013) John S. A. Mattick et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Distribution of the branched chain aminotransferase proteins in the human brain and their role in glutamate regulation

(2012) Jonathon Hull et al.   JOURNAL OF NEUROCHEMISTRY

Feasibility of an early Alzheimer's disease immunosignature diagnostic test

(2012) Lucas Restrepo et al.   JOURNAL OF NEUROIMMUNOLOGY

Glutamate system, amyloid β peptides and tau protein: functional interrelationships and relevance to Alzheimer disease pathology

(2012) Timothy Revett et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Blood and plasma-based proteomic biomarker research in Alzheimer's disease

(2012) Simone Lista et al.   PROGRESS IN NEUROBIOLOGY

Alzheimer's disease diagnostic criteria: practical applications

(2012) Jeffrey Cummings   Alzheimers Research & Therapy

Changes in plasma phenylalanine, isoleucine, leucine, and valine are associated with significant changes in intracranial pressure and jugular venous oxygen saturation in patients with severe traumatic brain injury

(2011) Raphael N. Vuille-Dit-Bille et al.   AMINO ACIDS

Validation of Plasma Branched Chain Amino Acids as Biomarkers in Huntington Disease

(2011) Fanny Mochel et al.   ARCHIVES OF NEUROLOGY

A Blood-Based Algorithm for the Detection of Alzheimer’s Disease

(2011) Sid E. O’Bryant et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Medical Foods for Alzheimerʼs Disease

(2011) Raj C. Shah   DRUGS & AGING

Advances in tau-based drug discovery

(2011) Wendy Noble et al.   Expert Opinion on Drug Discovery

Plasma Clusterin and the Risk of Alzheimer Disease

(2011) Elisabeth M. C. Schrijvers   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Serum Clusterin Levels Are Not Increased in Presymptomatic Alzheimer’s Disease

(2011) Linda IJsselstijn et al.   JOURNAL OF PROTEOME RESEARCH

Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: mechanism for deficient glutamatergic transmission?

(2011) Markel Olabarria et al.   Molecular Neurodegeneration

Preferential accumulation of amyloid-beta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex

(2011) Sophie Sokolow et al.   NEUROBIOLOGY OF DISEASE

Association of Plasma Clusterin Concentration With Severity, Pathology, and Progression in Alzheimer Disease

(2010) Madhav Thambisetty et al.   ARCHIVES OF GENERAL PSYCHIATRY

Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment: A Randomized Controlled Trial

(2010) A. David Smith et al.   PLoS One

Apolipoprotein E genotyping method by Real Time PCR, a fast and cost-effective alternative to the TaqMan® and FRET assays

(2009) Olga Calero et al.   JOURNAL OF NEUROSCIENCE METHODS

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY

Reduced hippocampal glutamate in Alzheimer disease

(2009) R. Rupsingh et al.   NEUROBIOLOGY OF AGING

Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease

(2007) Alireza Kashani et al.   NEUROBIOLOGY OF AGING