标题
Melatonin May Increase Anticancer Potential of Pleiotropic Drugs
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 12, Pages 3910
出版商
MDPI AG
发表日期
2018-12-07
DOI
10.3390/ijms19123910
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Melatonin Promotes Apoptosis of Oxaliplatin-resistant Colorectal Cancer Cells Through Inhibition of Cellular Prion Protein
- (2018) ANTICANCER RESEARCH
- Melatonin Promotes Apoptosis of Colorectal Cancer CellsviaSuperoxide-mediated ER Stress by Inhibiting Cellular Prion Protein Expression
- (2018) CHUL WON YUN et al. ANTICANCER RESEARCH
- Associations between aspirin use and the risk of cancers: a meta-analysis of observational studies
- (2018) Yan Qiao et al. BMC CANCER
- Metformin, Asian ethnicity and risk of prostate cancer in type 2 diabetes: a systematic review and meta-analysis
- (2018) Christopher B. Chen et al. BMC CANCER
- Melatonin and health: an umbrella review of health outcomes and biological mechanisms of action
- (2018) Pawel P. Posadzki et al. BMC Medicine
- Association of Metformin with Breast Cancer Incidence and Mortality in Patients with Type II Diabetes: A GRADE-Assessed Systematic Review and Meta-analysis
- (2018) Grace H. Tang et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Modeling Statin-Induced Reductions of Cardiovascular Events in Primary Prevention: A VOYAGER Meta-Analysis
- (2018) Björn W. Karlson et al. CARDIOLOGY
- Melatonin Synergizes with Sorafenib to Suppress Pancreatic Cancer via Melatonin Receptor and PDGFR-β/STAT3 Pathway
- (2018) Zhenghuan Fang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Melatonin and breast cancer: Evidences from preclinical and human studies
- (2018) Peter Kubatka et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Diabetes and cancer: Pathophysiological fundamentals of a ‘dangerous affair’
- (2018) Angelo Cignarelli et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Melatonin Inhibits the Proliferation of Gastric Cancer Cells Through Regulating the miR-16-5p-Smad3 Pathway
- (2018) Chenyu Zhu et al. DNA AND CELL BIOLOGY
- Simvastatin interferes with cancer 'stem-cell' plasticity reducing metastasis in ovarian cancer
- (2018) Sumie Kato et al. ENDOCRINE-RELATED CANCER
- Melatonin synthesis and clock gene regulation in the pineal organ of teleost fish compared to mammals: Similarities and differences
- (2018) Saurav Saha et al. GENERAL AND COMPARATIVE ENDOCRINOLOGY
- Melatonin: A Multifunctional Factor in Plants
- (2018) Jibiao Fan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melatonin Analogue Antiproliferative and Cytotoxic Effects on Human Prostate Cancer Cells
- (2018) Angela Calastretti et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Synergistic promoting effects of pentoxifylline and simvastatin on the apoptosis of triple-negative MDA-MB-231 breast cancer cells
- (2018) Yessica Castellanos-Esparza et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Simvastatin exerts anticancer effects in osteosarcoma cell lines via geranylgeranylation and c-Jun activation
- (2018) Shinwan Kany et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Melatonin and its metabolites vs oxidative stress: From individual actions to collective protection
- (2018) Annia Galano et al. JOURNAL OF PINEAL RESEARCH
- Does the use of melatonin overcome drug resistance in cancer chemotherapy?
- (2018) Mohammad Hossein Asghari et al. LIFE SCIENCES
- Mitochondria Transcription Factor A: A Putative Target for the Effect of Melatonin on U87MG Malignant Glioma Cell Line
- (2018) Daiane Franco et al. MOLECULES
- Melatonin: A Versatile Protector against Oxidative DNA Damage
- (2018) Annia Galano et al. MOLECULES
- Melatonin induces the apoptosis and inhibits the proliferation of human gastric cancer cells via blockade of the AKT/MDM2 pathway
- (2018) Jun Song et al. ONCOLOGY REPORTS
- Melatonin suppresses eosinophils and Th17 cells in hamsters treated with a combination of human liver fluke infection and a chemical carcinogen
- (2018) Wachanan Wongsena et al. Pharmacological Reports
- Does the association of prostate cancer with night-shift work differ according to rotating vs. fixed schedule? A systematic review and meta-analysis
- (2018) Jennifer Mancio et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Phytomelatonin, natural melatonin from plants as a novel dietary supplement: Sources, activities and world market
- (2018) Marino B. Arnao et al. Journal of Functional Foods
- Melatonin Treatment Regulates SIRT3 Expression in Early Brain Injury (EBI) Due to Reactive Oxygen Species (ROS) in a Mouse Model of Subarachnoid Hemorrhage (SAH)
- (2018) Song Yang et al. MEDICAL SCIENCE MONITOR
- Thiazolidinediones and risk of colorectal cancer in patients with diabetes mellitus: A meta-analysis
- (2018) Ting-Ting Hu et al. Saudi Journal of Gastroenterology
- Melatonin suppresses thyroid cancer growth and overcomes radioresistance via inhibition of p65 phosphorylation and induction of ROS
- (2018) Zhen-Wei Zou et al. Redox Biology
- Optimising treatment of hyperlipidaemia: Quantitative evaluation of UK, USA and European guidelines taking account of both LDL cholesterol levels and cardiovascular disease risk
- (2018) Handrean Soran et al. ATHEROSCLEROSIS
- The protective role of melatonin in chemotherapy‐induced nephrotoxicity: a systematic review of non-clinical studies
- (2018) Hamed Haghi-Aminjan et al. Expert Opinion on Drug Metabolism & Toxicology
- Clinically Relevant Anti-Inflammatory Agents for Chemoprevention of Colorectal Cancer: New Perspectives
- (2018) Altaf Mohammed et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Opportunities and Challenges of Peroxisome Proliferator-Activated Receptors Ligands in Clinical Drug Discovery and Development
- (2018) Fan Hong et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pleiotropic Effects of Metformin on Cancer
- (2018) Hans-Juergen Schulten INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Metformin: An Old Drug with New Applications
- (2018) Joseph Zhou et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Statins on hepatocellular carcinoma risk in hepatitis B or C patients protocol for a systematic review and meta-analysis
- (2018) Zhiguo Li et al. MEDICINE
- Statin Use and Cancer Incidence in Patients with Type 2 Diabetes Mellitus: A Network Meta-Analysis
- (2018) Yi-Bing Hu et al. Gastroenterology Research and Practice
- Dietary Melatonin Supplementation Could Be a Promising Preventing/Therapeutic Approach for a Variety of Liver Diseases
- (2018) Francesca Bonomini et al. Nutrients
- Melatonin-loaded silica coated with hydroxypropyl methylcellulose phthalate for enhanced oral bioavailability: Preparation, and in vitro-in vivo evaluation
- (2017) Yuanyuan Li et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Melatonin increases human cervical cancer HeLa cells apoptosis induced by cisplatin via inhibition of JNK/Parkin/mitophagy axis
- (2017) Li Chen et al. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
- Melatonin Inhibits Glioblastoma Stem-like cells through Suppression of EZH2-NOTCH1 Signaling Axis
- (2017) Xiangrong Zheng et al. International Journal of Biological Sciences
- Effects of Melatonin and Its Analogues on Pancreatic Inflammation, Enzyme Secretion, and Tumorigenesis
- (2017) Jolanta Jaworek et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melatonin Inhibits Androgen Receptor Splice Variant-7 (AR-V7)-Induced Nuclear Factor-Kappa B (NF-κB) Activation and NF-κB Activator-Induced AR-V7 Expression in Prostate Cancer Cells: Potential Implications for the Use of Melatonin in Castration-Resistant Prostate Cancer (CRPC) Therapy
- (2017) Vincent Liu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis
- (2017) Russel Reiter et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melatonin Reduces Angiogenesis in Serous Papillary Ovarian Carcinoma of Ethanol-Preferring Rats
- (2017) Yohan Zonta et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Circadian Clock, Cell Division, and Cancer: From Molecules to Organism
- (2017) Anton Shostak INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melatonin enhances the apoptotic effects and modulates the changes in gene expression induced by docetaxel in MCF‑7 human breast cancer cells
- (2017) Carolina Alonso-Gonz�lez et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Beneficial Effects of Adjuvant Melatonin in Minimizing Oral Mucositis Complications in Head and Neck Cancer Patients Receiving Concurrent Chemoradiation
- (2017) Kittipong Onseng et al. JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
- Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin Content
- (2017) Lauren A.E. Erland et al. Journal of Clinical Sleep Medicine
- The role of melatonin on chemotherapy-induced reproductive toxicity
- (2017) Hamed Haghi-Aminjan et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Melatonin regulates PARP1 to control the senescence-associated secretory phenotype (SASP) in human fetal lung fibroblast cells
- (2017) Songtao Yu et al. JOURNAL OF PINEAL RESEARCH
- Melatonin promotes sorafenib-induced apoptosis through synergistic activation of JNK/c-jun pathway in human hepatocellular carcinoma
- (2017) Shibo Lin et al. JOURNAL OF PINEAL RESEARCH
- Shift work, night work, and the risk of prostate cancer
- (2017) Hong-Bing Du et al. MEDICINE
- Melatonin inhibits angiogenesis in SH-SY5Y human neuroblastoma cells by downregulation of VEGF
- (2017) Alicia González et al. ONCOLOGY REPORTS
- Melatonin as an angiogenesis inhibitor to combat cancer: Mechanistic evidence
- (2017) Nasser Hashemi Goradel et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Simvastatin-induced cell cycle arrest through inhibition of STAT3/SKP2 axis and activation of AMPK to promote p27 and p21 accumulation in hepatocellular carcinoma cells
- (2017) Sin-Ting Wang et al. Cell Death & Disease
- What is known about melatonin, chemotherapy and altered gene expression in breast cancer
- (2017) Carlos Martínez-Campa et al. Oncology Letters
- Dietary Sources and Bioactivities of Melatonin
- (2017) Xiao Meng et al. Nutrients
- Prognostic significance of anti-diabetic medications in pancreatic cancer: A meta-analysis
- (2017) Dong-Chu Zhou et al. Oncotarget
- The impact of metformin use on survival in prostate cancer: a systematic review and meta-analysis
- (2017) Yao Xiao et al. Oncotarget
- Statin use and endometrial cancer risk: a meta-analysis
- (2017) Jing Yang et al. Oncotarget
- Mevastatin blockade of autolysosome maturation stimulates LBH589-induced cell death in triple-negative breast cancer cells
- (2017) Zhaohu Lin et al. Oncotarget
- Melatonin exerts anti-oral cancer effect via suppressing LSD1 in patient-derived tumor xenograft models
- (2017) Cheng-Yu Yang et al. Oncotarget
- Antiproliferative and pro-apoptotic activity of melatonin analogues on melanoma and breast cancer cells
- (2017) Giuliana Gatti et al. Oncotarget
- Melatonin for the prevention and treatment of cancer
- (2017) Ya Li et al. Oncotarget
- Nonsteroidal anti-inflammatory drugs (NSAIDs) and prostate cancer risk: results from the EPICAP study
- (2017) Solene Doat et al. Cancer Medicine
- Pioglitazone and the Risk of Bladder Cancer: A Meta-Analysis
- (2017) Elena Filipova et al. Diabetes Therapy
- PPAR-γ Agonists As Antineoplastic Agents in Cancers with Dysregulated IGF Axis
- (2017) Veronica Vella et al. Frontiers in Endocrinology
- Pioglitazone and the Risk of Bladder Cancer: A Meta-Analysis
- (2017) Elena Filipova et al. Diabetes Therapy
- NSAIDs Use and Reduced Metastasis in Cancer Patients: results from a meta-analysis
- (2017) Xiaoping Zhao et al. Scientific Reports
- The potential therapeutic effect of melatonin on human ovarian cancer by inhibition of invasion and migration of cancer stem cells
- (2017) Maryam Akbarzadeh et al. Scientific Reports
- Melatonin Regulates Angiogenic and Inflammatory Proteins in MDA-MB-231 Cell Line and in Co-culture with Cancer-associated Fibroblasts
- (2016) Larissa B. Maschio-Signorini et al. Anti-Cancer Agents in Medicinal Chemistry
- The current role of thiazolidinediones in diabetes management
- (2016) Christos V. Rizos et al. ARCHIVES OF TOXICOLOGY
- Pioglitazone together with imatinib in chronic myeloid leukemia: A proof of concept study
- (2016) Philippe Rousselot et al. CANCER
- Inhibition of ERK1/2 Signaling Pathway is Involved in Melatonin's Antiproliferative Effect on Human MG-63 Osteosarcoma Cells
- (2016) Lifeng Liu et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Metformin may protect nondiabetic breast cancer women from metastasis
- (2016) Sahar Mohammed EL-Haggar et al. CLINICAL & EXPERIMENTAL METASTASIS
- PIK3CA Mutation, Aspirin Use after Diagnosis and Survival of Colorectal Cancer. A Systematic Review and Meta-analysis of Epidemiological Studies
- (2016) L. Paleari et al. CLINICAL ONCOLOGY
- Low-dose Aspirin, Nonsteroidal Anti-inflammatory Drugs, Selective COX-2 Inhibitors and Breast Cancer Recurrence
- (2016) Deirdre P. Cronin-Fenton et al. EPIDEMIOLOGY
- Role of high-fat diet on the effect of pioglitazone and melatonin in a rat model of breast cancer
- (2016) Bianka Bojková et al. EUROPEAN JOURNAL OF CANCER PREVENTION
- Non-steroidal anti-inflammatory drug use and risk of endometrial cancer: A systematic review and meta-analysis of observational studies
- (2016) Freija Verdoodt et al. GYNECOLOGIC ONCOLOGY
- IGFBP3 and MAPK/ERK signaling mediates melatonin-induced antitumor activity in prostate cancer
- (2016) Juan C. Mayo et al. JOURNAL OF PINEAL RESEARCH
- Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κB DNA-binding activity
- (2016) Yung-Wei Lin et al. JOURNAL OF PINEAL RESEARCH
- Melatonin-induced increase in sensitivity of human hepatocellular carcinoma cells to sorafenib is associated with reactive oxygen species production and mitophagy
- (2016) Néstor Prieto-Domínguez et al. JOURNAL OF PINEAL RESEARCH
- Melatonin enhances arsenic trioxide-induced cell death via sustained upregulation of Redd1 expression in breast cancer cells
- (2016) Sun-Mi Yun et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Melatonin induces cell apoptosis in Mia PaCa-2 cells via the suppression of nuclear factor-κB and activation of ERK and JNK: A novel therapeutic implication for pancreatic cancer
- (2016) Weimin Li et al. ONCOLOGY REPORTS
- Retinoids and rexinoids in cancer prevention: from laboratory to clinic
- (2016) Iván P. Uray et al. SEMINARS IN ONCOLOGY
- Melatonin inhibits TPA-induced oral cancer cell migration by suppressing matrix metalloproteinase-9 activation through the histone acetylation
- (2016) Chia-Ming Yeh et al. Oncotarget
- Aspirin and non-steroidal anti-inflammatory drugs use reduce gastric cancer risk: A dose-response meta-analysis
- (2016) Xuan-zhang Huang et al. Oncotarget
- Pharmacokinetics of oral and intravenous melatonin in healthy volunteers
- (2016) Lars P. H. Andersen et al. BMC Pharmacology & Toxicology
- Evolution of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Cyclooxygenase (COX) Inhibition and Beyond
- (2016) Praveen Rao et al. JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
- Aspirin in the Treatment of Cancer: Reductions in Metastatic Spread and in Mortality: A Systematic Review and Meta-Analyses of Published Studies
- (2016) Peter C. Elwood et al. PLoS One
- Aspirin and nonsteroidal anti-inflammatory drugs after but not before diagnosis are associated with improved breast cancer survival: a meta-analysis
- (2015) Xuan-zhang Huang et al. CANCER CAUSES & CONTROL
- Cyclooxygenase-2 promotes tumor growth and suppresses tumor immunity
- (2015) Bing Liu et al. Cancer Cell International
- Aspirin, nonaspirin nonsteroidal anti-inflammatory drugs, acetaminophen and ovarian cancer survival
- (2015) Christina M. Nagle et al. Cancer Epidemiology
- Lack of Effect of Metformin on Mammary Carcinogenesis in Nondiabetic Rat and Mouse Models
- (2015) M. D. Thompson et al. Cancer Prevention Research
- Melatonin potentiates cisplatin-induced apoptosis and cell cycle arrest in human lung adenocarcinoma cells
- (2015) P. Plaimee et al. CELL PROLIFERATION
- Melatonin Induces Cell Apoptosis in AGS Cells Through the Activation of JNK and P38 MAPK and the Suppression of Nuclear Factor-Kappa B: a Novel Therapeutic Implication for Gastric Cancer
- (2015) Weimin Li et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- The Safety of Melatonin in Humans
- (2015) Lars Peter Holst Andersen et al. CLINICAL DRUG INVESTIGATION
- Thermodynamics and preliminary pharmaceutical characterization of a melatonin–pimelic acid cocrystal prepared by a melt crystallization method
- (2015) Yan Yan et al. CRYSTENGCOMM
- Melatonin: an inhibitor of breast cancer
- (2015) S. M. Hill et al. ENDOCRINE-RELATED CANCER
- Effects of Thiazolidinediones on metabolism and cancer: Relative influence of PPARγ and IGF-1 signaling
- (2015) Amreen Mughal et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Melatonin overcomes resistance to clofarabine in two leukemic cell lines by increased expression of deoxycytidine kinase
- (2015) Miho Yamanishi et al. EXPERIMENTAL HEMATOLOGY
- Night shift work, chronotype and prostate cancer risk in the MCC-Spain case-control study
- (2015) Kyriaki Papantoniou et al. INTERNATIONAL JOURNAL OF CANCER
- Determination of Melatonin in Rice (Oryza sativa) Grains by Pressurized Liquid Extraction
- (2015) Widiastuti Setyaningsih et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Melatonin overcomes gemcitabine resistance in pancreatic ductal adenocarcinoma by abrogating nuclear factor-κB activation
- (2015) Huai-Qiang Ju et al. JOURNAL OF PINEAL RESEARCH
- HDAC1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways
- (2015) Chongxi Fan et al. JOURNAL OF PINEAL RESEARCH
- Melatonin induces apoptosis of colorectal cancer cells through HDAC4 nuclear import mediated by CaMKII inactivation
- (2015) Jia-Yi Wei et al. JOURNAL OF PINEAL RESEARCH
- Melatonin sensitizes human cervical cancer HeLa cells to cisplatin-induced cytotoxicity and apoptosis: effects on oxidative stress and DNA fragmentation
- (2015) Roberto Pariente et al. JOURNAL OF PINEAL RESEARCH
- Melatonin: an ancient molecule that makes oxygen metabolically tolerable
- (2015) Lucien C. Manchester et al. JOURNAL OF PINEAL RESEARCH
- Functions of melatonin in plants: a review
- (2015) Marino B. Arnao et al. JOURNAL OF PINEAL RESEARCH
- Retinoic acid receptors: From molecular mechanisms to cancer therapy
- (2015) Alessandra di Masi et al. MOLECULAR ASPECTS OF MEDICINE
- Phytomelatonin: Assisting Plants to Survive and Thrive
- (2015) Russel Reiter et al. MOLECULES
- Involvement of nuclear receptor RZR/RORγ in melatonin-induced HIF-1α inactivation in SGC-7901 human gastric cancer cells
- (2015) RI-XIONG WANG et al. ONCOLOGY REPORTS
- Relationship Between the Use of Statins and Patient Survival in Colorectal Cancer: A Systematic Review and Meta-Analysis
- (2015) Heping Cai et al. PLoS One
- Metformin Induces Apoptosis and Downregulates Pyruvate Kinase M2 in Breast Cancer Cells Only When Grown in Nutrient-Poor Conditions
- (2015) Alessandra Silvestri et al. PLoS One
- Dysregulated metabolism contributes to oncogenesis
- (2015) Matthew D. Hirschey et al. SEMINARS IN CANCER BIOLOGY
- Agomelatine or ramelteon as treatment adjuncts in glioblastoma and other M1- or M2-expressing cancers
- (2015) Richard E. Kast Wspolczesna Onkologia-Contemporary Oncology
- Melatonin inhibits AP-2β/hTERT, NF-κB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells
- (2015) Jian-Jun Lu et al. Oncotarget
- Metformin for cancer and aging prevention: is it a time to make the long story short?
- (2015) Vladimir N. Anisimov Oncotarget
- Chemotherapy and Chemoprevention by Thiazolidinediones
- (2015) Eleonore Fröhlich et al. Biomed Research International
- Upregulation of miRNA3195 and miRNA374b Mediates the Anti-Angiogenic Properties of Melatonin in Hypoxic PC-3 Prostate Cancer Cells
- (2015) Eun Jung Sohn et al. Journal of Cancer
- Combination of Pitavastatin and melatonin shows partial antineoplastic effects in a rat breast carcinoma model
- (2014) Peter Kubatka et al. ACTA HISTOCHEMICA
- Risk of fracture with thiazolidinediones: An updated meta-analysis of randomized clinical trials
- (2014) Zhong-Ning Zhu et al. BONE
- Cyclooxygenase inhibitors use is associated with reduced risk of esophageal adenocarcinoma in patients with Barrett’s esophagus: a meta-analysis
- (2014) S Zhang et al. BRITISH JOURNAL OF CANCER
- Extrapineal melatonin: sources, regulation, and potential functions
- (2014) Darío Acuña-Castroviejo et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Statins in oncological research: From experimental studies to clinical practice
- (2014) Peter Kubatka et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Cancer Risk Among People With Type 1 and Type 2 Diabetes: Disentangling True Associations, Detection Bias, and Reverse Causation
- (2014) Jessica L. Harding et al. DIABETES CARE
- Pioglitazone and bladder cancer risk: a multipopulation pooled, cumulative exposure analysis
- (2014) Daniel Levin et al. DIABETOLOGIA
- Soft gel capsules improve melatonin’s bioavailability in humans
- (2014) Sara Proietti et al. Expert Opinion on Drug Metabolism & Toxicology
- Melatonin potentiates the anti-tumour effect of pravastatin in rat mammary gland carcinoma model
- (2014) Peter Orendáš et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- Melatonin reduces endothelin-1 expression and secretion in colon cancer cells through the inactivation of FoxO-1 and NF-κβ
- (2014) Josefa León et al. JOURNAL OF PINEAL RESEARCH
- Melatonin identified in meats and other food stuffs: potentially nutritional impact
- (2014) Dun-Xian Tan et al. JOURNAL OF PINEAL RESEARCH
- Melatonin: a well-documented antioxidant with conditional pro-oxidant actions
- (2014) Hong-Mei Zhang et al. JOURNAL OF PINEAL RESEARCH
- Positive and negative effects of glitazones in carcinogenesis: Experimental models vs. clinical practice
- (2014) Bianka Bojková et al. PATHOLOGY RESEARCH AND PRACTICE
- Melatonin Combined with Endoplasmic Reticulum Stress Induces Cell Death via the PI3K/Akt/mTOR Pathway in B16F10 Melanoma Cells
- (2014) Han Sung Kim et al. PLoS One
- Effect of Melatonin on Tumor Growth and Angiogenesis in Xenograft Model of Breast Cancer
- (2014) Bruna Victorasso Jardim-Perassi et al. PLoS One
- Mechanisms by Which Low Glucose Enhances the Cytotoxicity of Metformin to Cancer Cells Both In Vitro and In Vivo
- (2014) Yongxian Zhuang et al. PLoS One
- A pilot ‘window of opportunity’ neoadjuvant study of metformin in localised prostate cancer
- (2014) A M Joshua et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Antiproliferative and metabolic effects of metformin in a preoperative window clinical trial for endometrial cancer
- (2014) Kevin M. Schuler et al. Cancer Medicine
- Thiazolidinediones and cancer: results of a meta-analysis of randomized clinical trials
- (2013) Matteo Monami et al. ACTA DIABETOLOGICA
- Statins are associated with reduced risk of gastric cancer: a systematic review and meta-analysis
- (2013) P. P. Singh et al. ANNALS OF ONCOLOGY
- Atorvastatin inhibited Rho-associated kinase 1 (ROCK1) and focal adhesion kinase (FAK) mediated adhesion and differentiation of CD133+CD44+ prostate cancer stem cells
- (2013) Satyanarayana Rentala et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells
- (2013) Emelie Karnevi et al. BMC CANCER
- Does night work increase the risk of breast cancer? A systematic review and meta-analysis of epidemiological studies
- (2013) Yijun Jia et al. Cancer Epidemiology
- Molecular Pathways: Current Role and Future Directions of the Retinoic Acid Pathway in Cancer Prevention and Treatment
- (2013) R. M. Connolly et al. CLINICAL CANCER RESEARCH
- Diabetes Mellitus Increases the Risk of Bladder Cancer: An Updated Meta-Analysis of Observational Studies
- (2013) Hong Fang et al. Diabetes Technology & Therapeutics
- A Comparison of B16 Melanoma Cells and 3T3 Fibroblasts Concerning Cell Viability and ROS Production in the Presence of Melatonin, Tested Over a Wide Range of Concentrations
- (2013) Maria Bonmati-Carrion et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melatonin Anticancer Effects: Review
- (2013) Giuseppe Di Bella et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melatonin: Buffering the Immune System
- (2013) Antonio Carrillo-Vico et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Quantitative determination of melatonin in milk by LC-MS/MS
- (2013) Duraisamy Karunanithi et al. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
- Melatonin synthesis in rice seedlings in vivo is enhanced at high temperatures and under dark conditions due to increased serotoninN-acetyltransferase andN-acetylserotonin methyltransferase activities
- (2013) Yeong Byeon et al. JOURNAL OF PINEAL RESEARCH
- Transcriptional and post-translational regulation of Bim controls apoptosis in melatonin-treated human renal cancer Caki cells
- (2013) Eun Jung Park et al. JOURNAL OF PINEAL RESEARCH
- Melatonin induces apoptosis through a caspase-dependent but reactive oxygen species-independent mechanism in human leukemia Molt-3 cells
- (2013) Juan Perdomo et al. JOURNAL OF PINEAL RESEARCH
- Sulindac Selectively Inhibits Colon Tumor Cell Growth by Activating the cGMP/PKG Pathway to Suppress Wnt/ -Catenin Signaling
- (2013) N. Li et al. MOLECULAR CANCER THERAPEUTICS
- Unknown
- (2013) Christos Savvidis et al. MOLECULAR MEDICINE
- Cytochrome P450 Family 1 Inhibitors and Structure-Activity Relationships
- (2013) Jiawang Liu et al. MOLECULES
- Cancer Risk for Patients Using Thiazolidinediones for Type 2 Diabetes: A Meta-Analysis
- (2013) C. Bosetti et al. ONCOLOGIST
- Melatonin modulates aromatase activity and expression in endothelial cells
- (2013) VIRGINIA ALVAREZ-GARCÍA et al. ONCOLOGY REPORTS
- Simvastatin Inhibits Proliferation and Induces Apoptosis in Human Lung Cancer Cells
- (2013) Xiaofeng Yu et al. ONCOLOGY RESEARCH
- High-Dose Aspirin Consumption Contributes to Decreased Risk for Pancreatic Cancer in a Systematic Review and Meta-analysis
- (2013) Xi-Jun Cui et al. PANCREAS
- Repositioning metformin for cancer prevention and treatment
- (2013) Brendan J. Quinn et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- COX-Independent Mechanisms of Cancer Chemoprevention by Anti-Inflammatory Drugs
- (2013) Evrim Gurpinar et al. Frontiers in Oncology
- Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study
- (2012) Saroj Niraula et al. BREAST CANCER RESEARCH AND TREATMENT
- PPARgamma inhibits hepatocellular carcinoma metastases in vitro and in mice
- (2012) B Shen et al. BRITISH JOURNAL OF CANCER
- The efficacy and safety of melatonin in concurrent chemotherapy or radiotherapy for solid tumors: a meta-analysis of randomized controlled trials
- (2012) Ye-min Wang et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Phase I trial of exemestane in combination with metformin and rosiglitazone in nondiabetic obese postmenopausal women with hormone receptor–positive metastatic breast cancer
- (2012) Francisco J. Esteva et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Melatonin, A Natural Programmed Cell Death Inducer in Cancer
- (2012) M. Sánchez-Hidalgo et al. CURRENT MEDICINAL CHEMISTRY
- Preventive effects of fluvastatin in rat mammary carcinogenesis
- (2012) Peter Kubatka et al. EUROPEAN JOURNAL OF CANCER PREVENTION
- Melatonin uses in oncology: breast cancer prevention and reduction of the side effects of chemotherapy and radiation
- (2012) Emilio J Sanchez-Barcelo et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Metformin decreases hepatocellular carcinoma risk in a dose-dependent manner: population-based and in vitro studies
- (2012) Hsiao-Ping Chen et al. GUT
- Melatonin enhances thapsigargin-induced apoptosis through reactive oxygen species-mediated upregulation of CCAAT-enhancer-binding protein homologous protein in human renal cancer cells
- (2012) Kyoung-jin Min et al. JOURNAL OF PINEAL RESEARCH
- Phenotypic changes caused by melatonin increased sensitivity of prostate cancer cells to cytokine-induced apoptosis
- (2012) Aida Rodriguez-Garcia et al. JOURNAL OF PINEAL RESEARCH
- Serum melatonin levels and antioxidant capacities after consumption of pineapple, orange, or banana by healthy male volunteers
- (2012) Manit Sae-Teaw et al. JOURNAL OF PINEAL RESEARCH
- Melatonin inhibits matrix metalloproteinase-9 activity by binding to its active site
- (2012) Deep Sankar Rudra et al. JOURNAL OF PINEAL RESEARCH
- Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials
- (2012) Peter M Rothwell et al. LANCET
- Aspirin and non-aspirin non-steroidal anti-inflammatory drug use and risk of lung cancer
- (2012) Wei-Yen Lim et al. LUNG CANCER
- The Antidiabetic Drug Metformin Inhibits Gastric Cancer Cell Proliferation In Vitro and In Vivo
- (2012) K. Kato et al. MOLECULAR CANCER THERAPEUTICS
- Role of mammary epithelial and stromal P450 enzymes in the clearance and metabolic activation of 7,12-dimethylbenz(a)anthracene in mice
- (2012) Yang Lin et al. TOXICOLOGY LETTERS
- Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy
- (2012) W-Y Shi et al. Cell Death & Disease
- Emerging PPARγ-Independent Role of PPARγLigands in Lung Diseases
- (2012) Ajit A. Kulkarni et al. PPAR Research
- Glioma-Initiating Cell Elimination by Metformin Activation of FOXO3 via AMPK
- (2012) Atsushi Sato et al. Stem Cells Translational Medicine
- Non-Steroidal Anti-Inflammatory Drugs and Colorectal Cancer Risk in a Large, Prospective Cohort
- (2011) Elizabeth H Ruder et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Metformin and thiazolidinediones are associated with improved breast cancer-specific survival of diabetic women with HER2+ breast cancer
- (2011) X. He et al. ANNALS OF ONCOLOGY
- Thiazolidinediones and metformin associated with improved survival of diabetic prostate cancer patients
- (2011) X.- X. He et al. ANNALS OF ONCOLOGY
- Prostaglandins and Inflammation
- (2011) Emanuela Ricciotti et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Antitumor effects of atorvastatin in the chemoprevention of rat mammary carcinogenesis
- (2011) Peter Kubatka et al. BIOLOGIA
- Peroxisome proliferator-activated receptors and cancer: challenges and opportunities
- (2011) Jihan Youssef et al. BRITISH JOURNAL OF PHARMACOLOGY
- Melatonin and Metformin Inhibit Skin Carcinogenesis and Lipid Peroxidation Induced by Benz(a)pyrene in Female Mice
- (2011) T. A. Man’cheva et al. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
- Inhibition of PDE5 by Sulindac Sulfide Selectively Induces Apoptosis and Attenuates Oncogenic Wnt/ -Catenin-Mediated Transcription in Human Breast Tumor Cells
- (2011) H. N. Tinsley et al. Cancer Prevention Research
- Coxibs and Other Nonsteroidal Anti-Inflammatory Drugs in Animal Models of Cancer Chemoprevention
- (2011) S. M. Fischer et al. Cancer Prevention Research
- Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro
- (2011) Irina N. Alimova et al. CELL CYCLE
- Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo
- (2011) Vladimir N. Anisimov et al. CELL CYCLE
- Basic Mechanisms Involved in the Anti-Cancer Effects of Melatonin
- (2011) M. D. Mediavilla et al. CURRENT MEDICINAL CHEMISTRY
- Breastfeeding may improve nocturnal sleep and reduce infantile colic: Potential role of breast milk melatonin
- (2011) Anat Cohen Engler et al. EUROPEAN JOURNAL OF PEDIATRICS
- Melatonin as Adjuvant Cancer Care With and Without Chemotherapy
- (2011) Dugald Seely et al. INTEGRATIVE CANCER THERAPIES
- Melatonin promotes differentiation of 3T3-L1 fibroblasts
- (2011) Alicia González et al. JOURNAL OF PINEAL RESEARCH
- Induction of cell differentiation and promotion of endocan gene expression in stomach cancer by melatonin
- (2011) Sumei Zhang et al. MOLECULAR BIOLOGY REPORTS
- Shift work and chronic disease: the epidemiological evidence
- (2011) X.-S. Wang et al. OCCUPATIONAL MEDICINE-OXFORD
- Phytomelatonin in the leaves and fruits of wild perennial plants
- (2011) Ram Zohar et al. Phytochemistry Letters
- Sulindac Sulfide Reverses Aberrant Self-Renewal of Progenitor Cells Induced by the AML-Associated Fusion Proteins PML/RARα and PLZF/RARα
- (2011) Gunnar Steinert et al. PLoS One
- Rosiglitazone Revisited
- (2010) Steven E. Nissen et al. ARCHIVES OF INTERNAL MEDICINE
- Colon Tumor Cell Growth-Inhibitory Activity of Sulindac Sulfide and Other Nonsteroidal Anti-Inflammatory Drugs Is Associated with Phosphodiesterase 5 Inhibition
- (2010) H. N. Tinsley et al. Cancer Prevention Research
- Metformin Suppresses Colorectal Aberrant Crypt Foci in a Short-term Clinical Trial
- (2010) K. Hosono et al. Cancer Prevention Research
- From carrot to clinic: an overview of the retinoic acid signaling pathway
- (2010) Maria Theodosiou et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Determination of melatonin in wine and plant extracts by capillary electrochromatography with immobilized carboxylic multi-walled carbon nanotubes as stationary phase
- (2010) Patricia W. Stege et al. ELECTROPHORESIS
- Pioglitazone in chemically induced mammary carcinogenesis in rats
- (2010) Bianka Bojková et al. EUROPEAN JOURNAL OF CANCER PREVENTION
- Melatonin and celecoxib improve the outcomes in hamsters with experimental pancreatic cancer
- (2010) Francisco J. Padillo et al. JOURNAL OF PINEAL RESEARCH
- Melatonin, a novel Sirt1 inhibitor, imparts antiproliferative effects against prostate cancer in vitro in culture and in vivo in TRAMP model
- (2010) Brittney Jung-Hynes et al. JOURNAL OF PINEAL RESEARCH
- Melatonin inhibits mitogenic cross-talk between retinoic acid-related orphan receptor alpha (RORα) and ERα in MCF-7 human breast cancer cells
- (2010) Chunmin Dong et al. STEROIDS
- Melatonin and Doxorubicin synergistically induce cell apoptosis in human hepatoma cell lines
- (2010) Lu-Lu Fan WORLD JOURNAL OF GASTROENTEROLOGY
- Chronic Lymphocytic Leukemia: Long-Lasting Remission with Combination of Cyclophosphamide, Somatostatin, Bromocriptine, Retinoids, Melatonin, and ACTH
- (2009) Mauro Todisco CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
- Diabetes and cancer
- (2009) Paolo Vigneri et al. ENDOCRINE-RELATED CANCER
- Nanoparticle-based targeted drug delivery
- (2009) Rajesh Singh et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Membrane-bound melatonin receptor MT1 down-regulates estrogen responsive genes in breast cancer cells
- (2009) Rainer Girgert et al. JOURNAL OF PINEAL RESEARCH
- Chemical stress by different agents affects the melatonin content of barley roots
- (2009) Marino B. Arnao et al. JOURNAL OF PINEAL RESEARCH
- A Phase I Study of Bexarotene and Rosiglitazone in Patients with Refractory Cancers
- (2008) William L. Read et al. CHEMOTHERAPY
- In vitro metformin anti-neoplastic activity in epithelial ovarian cancer
- (2008) Walter H. Gotlieb et al. GYNECOLOGIC ONCOLOGY
- Therapeutic Actions of Melatonin in Cancer: Possible Mechanisms
- (2008) Venkataramanujan Srinivasan et al. INTEGRATIVE CANCER THERAPIES
- Selective estrogen enzyme modulator actions of melatonin in human breast cancer cells
- (2008) A. Gonzalez et al. JOURNAL OF PINEAL RESEARCH
- Combination of melatonin and a peroxisome proliferator-activated receptor-γ agonist induces apoptosis in a breast cancer cell line
- (2008) Ahmet Korkmaz et al. JOURNAL OF PINEAL RESEARCH
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started