Effects of stably incorporated iron on protein phosphatase-1 structure and activity

A Sephin1-insensitive tripartite holophosphatase dephosphorylates translation initiation factor 2α

(2018) Ana Crespillo-Casado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

To what extent do structural changes in catalytic metal sites affect enzyme function?

(2018) Yana Valasatava et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Metal homeostasis and resistance in bacteria

(2017) Pete Chandrangsu et al.   NATURE REVIEWS MICROBIOLOGY

Decoding the selectivity of eIF2α holophosphatases and PPP1R15A inhibitors

(2017) Marta Carrara et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Decoding the selectivity of eIF2α holophosphatases and PPP1R15A inhibitors

(2017) Marta Carrara et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz

(2017) Ana Crespillo-Casado et al.   eLife

Synthesis of Highly Selective Submicromolar Microcystin-Based Inhibitors of Protein Phosphatase (PP)2A over PP1

(2016) Miriam Fontanillo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2 -mediated stress signaling

(2016) C. X. Santos et al.   EMBO JOURNAL

Metals in the active site of native protein phosphatase-1

(2015) Ewald Heroes et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit

(2015) I. Das et al.   SCIENCE

Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code

(2014) M. S. Choy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of a Peptide that Selectively Activates Protein Phosphatase-1 in Living Cells

(2012) Jayanta Chatterjee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 Holoenzyme

(2012) Nichole O'Connell et al.   STRUCTURE

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Presenting your structures: theCCP4mgmolecular-graphics software

(2011) S. McNicholas et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Selective Inhibition of a Regulatory Subunit of Protein Phosphatase 1 Restores Proteostasis

(2011) P. Tsaytler et al.   SCIENCE

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

(2010) Michael J Ragusa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal Structures of Protein Phosphatase-1 Bound to Nodularin-R and Tautomycin: A Novel Scaffold for Structure-based Drug Design of Serine/Threonine Phosphatase Inhibitors

(2008) Matthew S. Kelker et al.   JOURNAL OF MOLECULAR BIOLOGY