Loss of GINS2 inhibits cell proliferation and tumorigenesis in human gliomas

Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma

(2018) Bo Han et al.   CANCER LETTERS

Fluoride induces apoptosis via inhibiting SIRT1 activity to activate mitochondrial p53 pathway in human neuroblastoma SH-SY5Y cells

(2018) Wei Tu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Cdc45/RecJ-like protein forms a complex with GINS and MCM, and is important for DNA replication in Thermococcus kodakarensis

(2017) Mariko Nagata et al.   NUCLEIC ACIDS RESEARCH

Silencing of ATM expression by siRNA technique contributes to glioma stem cell radiosensitivity in vitro and in vivo

(2017) Yan Li et al.   ONCOLOGY REPORTS

GINS2 is a novel prognostic biomarker and promotes tumor progression in early-stage cervical cancer

(2017) Fei Ouyang et al.   ONCOLOGY REPORTS

Specific amplifications and copy number decreases during human neural stem cells differentiation towards astrocytes, neurons and oligodendrocytes

(2017) Ulrike Fischer et al.   Oncotarget

MicroRNA16 regulates glioma cell proliferation, apoptosis and invasion by targeting Wip1-ATM-p53 feedback loop

(2017) Xiao-Hong Zhan et al.   Oncotarget

MicroRNA203a suppresses glioma tumorigenesis through an ATM-dependent interferon response pathway

(2017) Chuan He Yang et al.   Oncotarget

BET bromodomain is a novel regulator of TAZ and its activity

(2016) Qiong Duan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

GINS2 regulates matrix metallopeptidase 9 expression and cancer stem cell property in human triple negative Breast cancer

(2016) Liang Peng et al.   BIOMEDICINE & PHARMACOTHERAPY

Archaeal orthologs of Cdc45 and GINS form a stable complex that stimulates the helicase activity of MCM

(2016) Yuli Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation

(2016) Sophia M Blake et al.   eLife

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

(2015) Yu Sun et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Loss of Diacylglycerol Kinase-Ζ Inhibits Cell Proliferation and Survival in Human Gliomas

(2015) Jinfu Diao et al.   MOLECULAR NEUROBIOLOGY

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis

(2015) Hongtan Wu et al.   Nature Communications

Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance

(2015) Malin Wickström et al.   Nature Communications

High GINS2 transcript level predicts poor prognosis and correlates with high histological grade and endocrine therapy resistance through mammary cancer stem cells in breast cancer patients

(2014) Ming Zheng et al.   BREAST CANCER RESEARCH AND TREATMENT

A glioma classification scheme based on coexpression modules of EGFR and PDGFRA

(2014) Yingyu Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of GINS2 on Proliferation and Apoptosis in Leukemic Cell Line

(2013) Xi Zhang et al.   International Journal of Medical Sciences

Glioblastoma and Other Malignant Gliomas

(2013) Antonio Omuro   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Protein interaction and cellular localization of human CDC45

(2013) Junichiro Takaya et al.   JOURNAL OF BIOCHEMISTRY

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2006-2010

(2013) Q. T. Ostrom et al.   NEURO-ONCOLOGY

An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells

(2013) D. Rohle et al.   SCIENCE

Evading apoptosis in cancer

(2013) Kaleigh Fernald et al.   TRENDS IN CELL BIOLOGY

Identification of TNM stage-specific genes in lung adenocarcinoma by genome-wide expression profiling

(2013) MING LIU et al.   Oncology Letters

Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase   in rolling circle DNA synthesis

(2012) Y.-H. Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetics of adult glioma

(2012) McKinsey L. Goodenberger et al.   Cancer Genetics

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The Accuracy of Survival Time Prediction for Patients with Glioma Is Improved by Measuring Mitotic Spindle Checkpoint Gene Expression

(2011) Li Bie et al.   PLoS One

Cancer stem cells in solid tumors: Is ‘evading apoptosis’ a hallmark of cancer?

(2011) Heiko Enderling et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Exciting New Advances in Neuro-Oncology: The Avenue to a Cure for Malignant Glioma

(2010) E. G. Van Meir et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Survival of Patients with Newly Diagnosed Glioblastoma Treated with Radiation and Temozolomide in Research Studies in the United States

(2010) S. A. Grossman et al.   CLINICAL CANCER RESEARCH

Up-regulation of PSF1 promotes the growth of breast cancer cells

(2010) Izumi Nakahara et al.   GENES TO CELLS

The Pathobiology of Glioma Tumors

(2009) Candece L. Gladson et al.   Annual Review of Pathology-Mechanisms of Disease

IDH1andIDH2Mutations in Gliomas

(2009) Hai Yan et al.   NEW ENGLAND JOURNAL OF MEDICINE