Citrate targets FBPase and constitutes an emerging novel approach for cancer therapy

Targeting FBPase is an emerging novel approach for cancer therapy

(2018) Gao-Min Liu et al.   Cancer Cell International

Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras

(2017) Ken Peeters et al.   Nature Communications

Citrate Suppresses Tumor Growth in Multiple Models through Inhibition of Glycolysis, the Tricarboxylic Acid Cycle and the IGF-1R Pathway

(2017) Jian-Guo Ren et al.   Scientific Reports

The reduced concentration of citrate in cancer cells: An indicator of cancer aggressiveness and a possible therapeutic target

(2016) Icard Philippe et al.   DRUG RESISTANCE UPDATES

Crystal structure of heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) and the inhibitory influence of citrate on substrate binding

(2016) Robert B. Crochet et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Nuclear Targeting of 6-Phosphofructo-2-kinase (PFKFB3) Increases Proliferation via Cyclin-dependent Kinases

(2009) Abdullah Yalcin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY