Targeting cellular metabolism using rapamycin and/or doxycycline enhances anti-tumour effects in human glioma cells
出版年份 2018 全文链接
标题
Targeting cellular metabolism using rapamycin and/or doxycycline enhances anti-tumour effects in human glioma cells
作者
关键词
Glioblastoma, mTOR inhibitor, Anti-metabolic drug combinations, Tumour metabolism, Rapamycin, Doxycycline, Temozolomide
出版物
Cancer Cell International
Volume 18, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-12-19
DOI
10.1186/s12935-018-0710-0
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors
- (2018) Debangshu Samanta et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- The pro-tumorigenic effects of metabolic alterations in glioblastoma including brain tumor initiating cells
- (2018) Catherine J. Libby et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- mTOR inhibition in glioblastoma: requiem for a dream?
- (2018) Sam Babak et al. NEURO-ONCOLOGY
- The Effects of Different mTOR Inhibitors in EGFR Inhibitor Resistant Colon Carcinoma Cells
- (2018) Tamás Sticz et al. PATHOLOGY & ONCOLOGY RESEARCH
- Temozolomide, sirolimus and chloroquine is a new therapeutic combination that synergizes to disrupt lysosomal function and cholesterol homeostasis in GBM cells
- (2018) Sanford Hsu et al. Oncotarget
- Anti-Angiogenics: Their Role in the Treatment of Glioblastoma
- (2018) Frank Winkler et al. Oncology Research and Treatment
- Rapamycin (mTORC1 inhibitor) reduces the production of lactate and 2-hydroxyglutarate oncometabolites in IDH1 mutant fibrosarcoma cells
- (2017) Zoltán Hujber et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Proteome Analysis of Hypoxic Glioblastoma Cells Reveals Sequential Metabolic Adaptation of One-Carbon Metabolic Pathways
- (2017) Kangling Zhang et al. MOLECULAR & CELLULAR PROTEOMICS
- Recent advances in the use of PI3K inhibitors for glioblastoma multiforme: current preclinical and clinical development
- (2017) Hua-fu Zhao et al. Molecular Cancer
- Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy
- (2017) Xinjian Li et al. MOLECULAR CELL
- Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs)
- (2017) Ernestina Marianna De Francesco et al. Oncotarget
- Induction of Mitochondrial Dysfunction and Oxidative Damage by Antibiotic Drug Doxycycline Enhances the Responsiveness of Glioblastoma to Chemotherapy
- (2017) Qian Tan et al. MEDICAL SCIENCE MONITOR
- EGFR Family Members’ Regulation of Autophagy Is at a Crossroads of Cell Survival and Death in Cancer
- (2017) Elizabeth Henson et al. Cancers
- Evolving Significance and Future Relevance of Anti-Angiogenic Activity of mTOR Inhibitors in Cancer Therapy
- (2017) Seraina Faes et al. Cancers
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- Characterisation of bioenergetic pathways and related regulators by multiple assays in human tumour cells
- (2016) A. Jeney et al. Cancer Cell International
- PI3K–mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models
- (2016) Fan Lin et al. CLINICAL CANCER RESEARCH
- Identification of Small Molecule Inhibitors of Human CytochromecOxidase That Target Chemoresistant Glioma Cells
- (2016) Claudia R. Oliva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting autophagy to sensitive glioma to temozolomide treatment
- (2016) Yuanliang Yan et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Clinical aggressiveness of malignant gliomas is linked to augmented metabolism of amino acids
- (2016) Eduard H. Panosyan et al. JOURNAL OF NEURO-ONCOLOGY
- Fatty acid oxidation is required for the respiration and proliferation of malignant glioma cells
- (2016) Hua Lin et al. NEURO-ONCOLOGY
- Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma
- (2016) Wei Jiang et al. Oncotarget
- Fundamentals of cancer metabolism
- (2016) R. J. DeBerardinis et al. Science Advances
- Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
- (2015) Zachary T. Schug et al. CANCER CELL
- NVP-BEZ235, a novel dual PI3K–mTOR inhibitor displays anti-glioma activity and reduces chemoresistance to temozolomide in human glioma cells
- (2015) Zhiyun Yu et al. CANCER LETTERS
- Doxycycline reduces the migration of tuberous sclerosis complex-2 null cells - effects on RhoA-GTPase and focal adhesion kinase
- (2015) Ho Yin Ng et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Tumor Cells Switch to Mitochondrial Oxidative Phosphorylation under Radiation via mTOR-Mediated Hexokinase II Inhibition - A Warburg-Reversing Effect
- (2015) Chung-Ling Lu et al. PLoS One
- Metformin Inhibits Growth of Human Glioblastoma Cells and Enhances Therapeutic Response
- (2015) Julie Sesen et al. PLoS One
- Determination of energy metabolites in cancer cells by porous graphitic carbon liquid chromatography electrospray ionization mass spectrometry for the assessment of energy metabolism
- (2014) Norbert Szoboszlai et al. ANALYTICA CHIMICA ACTA
- Lipid Catabolism via CPT1 as a Therapeutic Target for Prostate Cancer
- (2014) I. R. Schlaepfer et al. MOLECULAR CANCER THERAPEUTICS
- Elevated expression of fatty acid synthase and nuclear localization of carnitine palmitoyltransferase 1C are common among human gliomas
- (2014) Tomihiro Wakamiya et al. NEUROPATHOLOGY
- The Somatic Genomic Landscape of Glioblastoma
- (2013) Cameron W. Brennan et al. CELL
- Valproic Acid Downregulates the Expression of MGMT and Sensitizes Temozolomide-Resistant Glioma Cells
- (2012) Chung Heon Ryu et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells
- (2011) E. L. Kim et al. NEURO-ONCOLOGY
- Acquisition of Temozolomide Chemoresistance in Gliomas Leads to Remodeling of Mitochondrial Electron Transport Chain
- (2010) Claudia R. Oliva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started