标题
Cancer-associated mucins: role in immune modulation and metastasis
作者
关键词
Mucins, Immunomodulation, Cancer, Inflammation, Vaccine
出版物
CANCER AND METASTASIS REVIEWS
Volume -, Issue -, Pages -
出版商
Springer Nature
发表日期
2019-01-09
DOI
10.1007/s10555-018-09775-0
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- MUC4 mucin- a therapeutic target for pancreatic ductal adenocarcinoma
- (2017) Shailendra K. Gautam et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer
- (2017) Vinod P. Balachandran et al. NATURE
- Membrane Mucin Muc4 promotes blood cell association with tumor cells and mediates efficient metastasis in a mouse model of breast cancer
- (2017) A R Rowson-Hodel et al. ONCOGENE
- Safety, tumor trafficking and immunogenicity of chimeric antigen receptor (CAR)-T cells specific for TAG-72 in colorectal cancer
- (2017) Kristen M. Hege et al. Journal for ImmunoTherapy of Cancer
- Mucin 2 silencing promotes colon cancer metastasis through interleukin-6 signaling
- (2017) Hui-Ping Hsu et al. Scientific Reports
- A phase I study of PankoMab-GEX, a humanised glyco-optimised monoclonal antibody to a novel tumour-specific MUC1 glycopeptide epitope in patients with advanced carcinomas
- (2016) W. Fiedler et al. EUROPEAN JOURNAL OF CANCER
- Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma
- (2016) Avery D. Posey et al. IMMUNITY
- TG4010 immunotherapy and first-line chemotherapy for advanced non-small-cell lung cancer (TIME): results from the phase 2b part of a randomised, double-blind, placebo-controlled, phase 2b/3 trial
- (2016) Elisabeth Quoix et al. LANCET ONCOLOGY
- MUC5AC interactions with integrin β4 enhances the migration of lung cancer cells through FAK signaling
- (2016) I Lakshmanan et al. ONCOGENE
- Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps
- (2016) J. Park et al. Science Translational Medicine
- Selectins: initiators of leucocyte adhesion and signalling at the vascular wall
- (2015) Rodger P. McEver CARDIOVASCULAR RESEARCH
- Antibody Induction Directed against the Tumor-Associated MUC4 Glycoprotein
- (2015) Hui Cai et al. CHEMBIOCHEM
- 90 Y-clivatuzumab tetraxetan with or without low-dose gemcitabine: A phase Ib study in patients with metastatic pancreatic cancer after two or more prior therapies
- (2015) Vincent J. Picozzi et al. EUROPEAN JOURNAL OF CANCER
- A novel monoclonal antibody to a defined peptide epitope in MUC16
- (2015) Lara Marcos-Silva et al. GLYCOBIOLOGY
- Suppression of Toll-like receptor-mediated innate immune responses at the ocular surface by the membrane-associated mucins MUC1 and MUC16
- (2015) B B Menon et al. Mucosal Immunology
- Salivary mucins induce a Toll-like receptor 4-mediated pro-inflammatory response in human submandibular salivary cells: are mucins involved in Sjögren’s syndrome?
- (2015) María-José Barrera et al. RHEUMATOLOGY
- Novel HER3/MUC4 oncogenic signaling aggravates the tumorigenic phenotypes of pancreatic cancer cells
- (2015) Imayavaramban Lakshmanan et al. Oncotarget
- Mucin 1-specific B cell immune responses and their impact on overall survival in breast cancer patients
- (2015) Carlo Fremd et al. OncoImmunology
- MUC1 Protein Induces Urokinase-type Plasminogen Activator (uPA) by Forming a Complex with NF-κB p65 Transcription Factor and Binding to the uPA Promoter, Leading to Enhanced Invasiveness of Cancer Cells
- (2014) Yugo Mori et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress
- (2014) Mildred Felder et al. Molecular Cancer
- Pancreatic cancer counterattack: MUC4 mediates Fas-independent apoptosis of antigen-specific cytotoxic T lymphocyte
- (2014) YI ZHU et al. ONCOLOGY REPORTS
- The Role of PAM4 in the Management of Pancreatic Cancer: Diagnosis, Radioimmunodetection, and Radioimmunotherapy
- (2014) Suxia Han et al. Journal of Immunology Research
- Altered Tumor-Cell Glycosylation Promotes Metastasis
- (2014) Irina Häuselmann et al. Frontiers in Oncology
- Anti-tumor activity of a novel monoclonal antibody, NPC-1C, optimized for recognition of tumor antigen MUC5AC variant in preclinical models
- (2013) Sandip Pravin Patel et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- MUC5AC protects pancreatic cancer cells from TRAIL-induced death pathways
- (2013) HIROTAKA HOSHI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Mapping PAM4 (clivatuzumab), a monoclonal antibody in clinical trials for early detection and therapy of pancreatic ductal adenocarcinoma, to MUC5AC mucin
- (2013) David V Gold et al. Molecular Cancer
- Mucins in pancreatic cancer and its microenvironment
- (2013) Sukhwinder Kaur et al. Nature Reviews Gastroenterology & Hepatology
- Tumour Immunomodulation: Mucins in Resistance to Initiation and Maturation of Immune Response Against Tumours
- (2013) A. AnandKumar et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals
- (2013) M. Shan et al. SCIENCE
- Mesothelin Binding to CA125/MUC16 Promotes Pancreatic Cancer Cell Motility and Invasion via MMP-7 Activation
- (2013) Shih-Hsun Chen et al. Scientific Reports
- Mucins and Toll-like receptors: Kith and kin in infection and cancer
- (2012) Shikha Tarang et al. CANCER LETTERS
- Cancer Associated Aberrant Protein O-Glycosylation Can Modify Antigen Processing and Immune Response
- (2012) Caroline B. Madsen et al. PLoS One
- Immunotherapy with IL-10- and IFN-γ-producing CD4 effector cells modulate “Natural” and “Inducible” CD4 TReg cell subpopulation levels: observations in four cases of patients with ovarian cancer
- (2011) Mark J. Dobrzanski et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Randomized Phase II Trial of Letrozole plus Anti-MUC1 Antibody AS1402 in Hormone Receptor-Positive Locally Advanced or Metastatic Breast Cancer
- (2011) N. K. Ibrahim et al. CLINICAL CANCER RESEARCH
- Treatment of Advanced Pancreatic Carcinoma with 90Y-Clivatuzumab Tetraxetan: A Phase I Single-Dose Escalation Trial
- (2011) S. A. Gulec et al. CLINICAL CANCER RESEARCH
- MUC1 peptide vaccine mediated antitumor activity in non-small cell lung cancer
- (2011) Sherven Sharma et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Mucin 16 is a functional selectin ligand on pancreatic cancer cells
- (2011) Shih-Hsun Chen et al. FASEB JOURNAL
- MUC16 (CA125) regulates epithelial ovarian cancer cell growth, tumorigenesis and metastasis
- (2011) Catherine Thériault et al. GYNECOLOGIC ONCOLOGY
- Therapeutic vaccination with TG4010 and first-line chemotherapy in advanced non-small-cell lung cancer: a controlled phase 2B trial
- (2011) Elisabeth Quoix et al. LANCET ONCOLOGY
- Preparation and biological evaluation of 177Lu conjugated PR81 for radioimmunotherapy of breast cancer
- (2011) Mojtaba Salouti et al. NUCLEAR MEDICINE AND BIOLOGY
- Monoclonal Antibodies Recognizing the Non-Tandem Repeat Regions of the Human Mucin MUC4 in Pancreatic Cancer
- (2011) Maneesh Jain et al. PLoS One
- Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine
- (2011) V. Lakshminarayanan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunomodulation of monocyte-derived dendritic cells through ligation of tumor-produced mucins to Siglec-9
- (2010) Mariko Ohta et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Bismuth-213 radioimmunotherapy with C595 anti–MUC1 monoclonal antibody in an ovarian cancer ascites model
- (2010) Emma Y. Song et al. CANCER BIOLOGY & THERAPY
- A phase II study of the cancer vaccine TG4010 alone and in combination with cytokines in patients with metastatic renal clear-cell carcinoma: clinical and immunological findings
- (2010) Stéphane Oudard et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Novel Interaction of MUC4 and Galectin: Potential Pathobiological Implications for Metastasis in Lethal Pancreatic Cancer
- (2010) S. Senapati et al. CLINICAL CANCER RESEARCH
- A Phase II Study of Tg4010 (Mva-Muc1-Il2) in Association with Chemotherapy in Patients with Stage III/IV Non-small Cell Lung Cancer
- (2010) Rodryg Ramlau et al. Journal of Thoracic Oncology
- MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells
- (2010) Jennifer AA Gubbels et al. Molecular Cancer
- Reactivity of a humanized antibody (hPankoMab) towards a tumor-related MUC1 epitope (TA-MUC1) with various human carcinomas
- (2010) Xiao-Na Fan et al. PATHOLOGY RESEARCH AND PRACTICE
- Radioimmunotherapy of Solid Tumors: Searching for the Right Target
- (2010) Hong Song et al. Current Drug Delivery
- Identification of an HLA-A*0201-restrictive CTL epitope from MUC4 for applicable vaccine therapy
- (2009) Junli Wu et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Deletion of the Mucin-Like Molecule Muc1 Enhances Dendritic Cell Activation in Response to Toll-Like Receptor Ligands
- (2009) Marc A. Williams et al. Journal of Innate Immunity
- Mucins in ovarian cancer diagnosis and therapy
- (2009) Subhash C Chauhan et al. Journal of Ovarian Research
- MUC4 Mucin Interacts with and Stabilizes the HER2 Oncoprotein in Human Pancreatic Cancer Cells
- (2008) P. Chaturvedi et al. CANCER RESEARCH
- MVA-MUC1-IL2 vaccine immunotherapy (TG4010) improves PSA doubling time in patients with prostate cancer with biochemical failure
- (2008) R. Dreicer et al. INVESTIGATIONAL NEW DRUGS
- Oregovomab Maintenance Monoimmunotherapy Does Not Improve Outcomes in Advanced Ovarian Cancer
- (2008) Jonathan Berek et al. JOURNAL OF CLINICAL ONCOLOGY
- Clinical potential of mucins in diagnosis, prognosis, and therapy of ovarian cancer
- (2008) Ajay P Singh et al. LANCET ONCOLOGY
- Identification of O-glycosylated decapeptides within the MUC1 repeat domain as potential MHC class I (A2) binding epitopes
- (2008) Tanja Ninkovic et al. MOLECULAR IMMUNOLOGY
- Mucin Dynamics in Intestinal Bacterial Infection
- (2008) Sara K. Lindén et al. PLoS One
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