Efficacy and safety of PAC-14028 cream - a novel, topical, nonsteroidal, selective TRPV1 antagonist in patients with mild-to-moderate atopic dermatitis: a phase IIb randomized trial
出版年份 2019 全文链接
标题
Efficacy and safety of PAC-14028 cream - a novel, topical, nonsteroidal, selective TRPV1 antagonist in patients with mild-to-moderate atopic dermatitis: a phase IIb randomized trial
作者
关键词
-
出版物
BRITISH JOURNAL OF DERMATOLOGY
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2019-01-09
DOI
10.1111/bjd.17455
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A novel, topical, nonsteroidal, TRPV1 antagonist, PAC-14028 cream improves skin barrier function and exerts anti-inflammatory action through modulating epidermal differentiation markers and suppressing Th2 cytokines in atopic dermatitis
- (2018) Ji-Hae Lee et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Emerging therapies for atopic dermatitis: TRPV1 antagonists
- (2018) Jonathan G. Bonchak et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Emerging therapies for atopic dermatitis: JAK inhibitors
- (2018) David G. Cotter et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Therapeutic pipeline for atopic dermatitis: End of the drought?
- (2017) Amy S. Paller et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Atopic Dermatitis in Adults: A Diagnostic Challenge
- (2017) JF Silvestre Salvador et al. JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
- Efficacy and safety of crisaborole ointment, a novel, nonsteroidal phosphodiesterase 4 (PDE4) inhibitor for the topical treatment of atopic dermatitis (AD) in children and adults
- (2016) Amy S. Paller et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Self-maintenance of neurogenic inflammation contributes to a vicious cycle in skin
- (2015) Olivier Gouin et al. EXPERIMENTAL DERMATOLOGY
- A comparison of radio-frequency biomotion sensors and actigraphy versus polysomnography for the assessment of sleep in normal subjects
- (2014) Emer O’Hare et al. Sleep and Breathing
- Itch and Pain in Adolescents are Associated with Suicidal Ideation: A Population-based Cross-sectional Study
- (2013) J Halvorsen et al. ACTA DERMATO-VENEREOLOGICA
- Mast cell activation contributes to sickle cell pathobiology and pain in mice
- (2013) L. Vincent et al. BLOOD
- A sensory neuron–expressed IL-31 receptor mediates T helper cell–dependent itch: Involvement of TRPV1 and TRPA1
- (2013) Ferda Cevikbas et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Development of PAC-14028, a novel transient receptor potential vanilloid type 1 (TRPV1) channel antagonist as a new drug for refractory skin diseases
- (2012) Kyung-Min Lim et al. ARCHIVES OF PHARMACAL RESEARCH
- Antipruritic Effects of TRPV1 Antagonist in Murine Atopic Dermatitis and Itching Models
- (2011) Jun-Won Yun et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Management of Itch in Atopic Dermatitis
- (2011) Judith Hong et al. SEMINARS IN CUTANEOUS MEDICINE AND SURGERY
- TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms
- (2009) N. Imamachi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Atopic Dermatitis
- (2008) Thomas Bieber NEW ENGLAND JOURNAL OF MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started