Dual roles of mitochondrial fusion gene FZO1 in yeast age asymmetry and in longevity mediated by a novel ATG32-dependent retrograde response

Daughters of the budding yeast from old mothers have shorter replicative lifespans but not total lifespans. Are DNA damage and rDNA instability the factors that determine longevity?

(2018) Mateusz Molon et al.   CELL CYCLE

Systematic mapping of contact sites reveals tethers and a function for the peroxisome-mitochondria contact

(2018) Nadav Shai et al.   Nature Communications

Human Ageing Genomic Resources: new and updated databases

(2017) Robi Tacutu et al.   NUCLEIC ACIDS RESEARCH

Identification of the Target of the Retrograde Response that Mediates Replicative Lifespan Extension in Saccharomyces cerevisiae

(2016) J. C. Jiang et al.   GENETICS

Orchestrating the network of molecular pathways affecting aging: Role of nonselective autophagy and mitophagy

(2016) Laura Knuppertz et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Mitochondrial anchorage and fusion contribute to mitochondrial inheritance and quality control in the budding yeast Saccharomyces cerevisiae

(2016) Ryo Higuchi-Sanabria et al.   MOLECULAR BIOLOGY OF THE CELL

The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1

(2016) Gino Heeren et al.   Aging-US

Mitochondria to nucleus signaling and the role of ceramide in its integration into the suite of cell quality control processes during aging

(2015) S.M. Jazwinski   AGEING RESEARCH REVIEWS

Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness

(2015) P. Katajisto et al.   SCIENCE

Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan

(2015) Dominik Bernhardt et al.   Scientific Reports

Stem cell aging: mechanisms, regulators and therapeutic opportunities

(2014) Juhyun Oh et al.   NATURE MEDICINE

Global Genetic Determinants of Mitochondrial DNA Copy Number

(2014) Hengshan Zhang et al.   PLoS One

Mitochondrial Aging and Age-Related Dysfunction of Mitochondria

(2014) Dimitry A. Chistiakov et al.   Biomed Research International

Molecular mechanisms underlying genotype-dependent responses to dietary restriction

(2013) Jennifer Schleit et al.   AGING CELL

Mitochondrial inheritance in yeast

(2013) Benedikt Westermann   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The Scaffold Protein Atg11 Recruits Fission Machinery to Drive Selective Mitochondria Degradation by Autophagy

(2013) Kai Mao et al.   DEVELOPMENTAL CELL

Mitochondrial Network Size Scaling in Budding Yeast

(2012) S. M. Rafelski et al.   SCIENCE

Loss of Mitochondrial Membrane Potential Triggers the Retrograde Response Extending Yeast Replicative Lifespan

(2012) Michael V. Miceli et al.   Frontiers in Genetics

Mitochondrial quality control during inheritance is associated with lifespan and mother-daughter age asymmetry in budding yeast

(2011) José Ricardo McFaline-Figueroa et al.   AGING CELL

Changes in reactive oxygen species begin early during replicative aging of Saccharomyces cerevisiae cells

(2011) Yuen T. Lam et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Fluorescence Microscopy Assay for Monitoring Mitophagy in the Yeast Saccharomyces cerevisiae

(2011) Dalibor Mijaljica et al.   Jove-Journal of Visualized Experiments

Quantitation of (a)symmetric inheritance of functional and of oxidatively damaged mitochondrial aconitase in the cell division of old yeast mother cells

(2010) Harald Klinger et al.   EXPERIMENTAL GERONTOLOGY

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy

(2009) Tomotake Kanki et al.   DEVELOPMENTAL CELL

Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy

(2009) Koji Okamoto et al.   DEVELOPMENTAL CELL

Aup1-mediated Regulation of Rtg3 during Mitophagy

(2009) Dikla Journo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Genomic Screen for Yeast Mutants Defective in Selective Mitochondria Autophagy

(2009) Tomotake Kanki et al.   MOLECULAR BIOLOGY OF THE CELL

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL