Treating Tumors at Low Drug Doses Using an Aptamer-Peptide Synergistic Drug Conjugate

Targeted Delivery of Auristatin-Modified Toxins to Pancreatic Cancer Using Aptamers

(2018) Christina Kratschmer et al.   Molecular Therapy-Nucleic Acids

A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer

(2017) Fangfei Li et al.   Nature Communications

A carrier-free dual-drug nanodelivery system functionalized with aptamer specific targeting HER2-overexpressing cancer cells

(2017) Kai Jiang et al.   Journal of Materials Chemistry B

Aptamer-Drug Conjugates of Active Metabolites of Nucleoside Analogs and Cytotoxic Agents Inhibit Pancreatic Tumor Cell Growth

(2017) Sorah Yoon et al.   Molecular Therapy-Nucleic Acids

Orthogonal Cysteine Protection Enables Homogeneous Multi-Drug Antibody-Drug Conjugates

(2016) Matthew R. Levengood et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multifunctional aptamer-based nanoparticles for targeted drug delivery to circumvent cancer resistance

(2016) Juan Liu et al.   BIOMATERIALS

DAFODIL: A novel liposome-encapsulated synergistic combination of doxorubicin and 5FU for low dose chemotherapy

(2016) Kathryn M. Camacho et al.   JOURNAL OF CONTROLLED RELEASE

Aptamers as targeted therapeutics: current potential and challenges

(2016) Jiehua Zhou et al.   NATURE REVIEWS DRUG DISCOVERY

Oligonucleotide aptamer-drug conjugates for targeted therapy of acute myeloid leukemia

(2015) Nianxi Zhao et al.   BIOMATERIALS

Synergistic antitumor activity of camptothecin–doxorubicin combinations and their conjugates with hyaluronic acid

(2015) Kathryn M. Camacho et al.   JOURNAL OF CONTROLLED RELEASE

A unique aptamer-drug conjugate for targeted therapy of multiple myeloma

(2015) J Wen et al.   LEUKEMIA

Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation

(2014) Craig S. McKay et al.   CHEMISTRY & BIOLOGY

Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy

(2014) Hongguang Sun et al.   Molecular Therapy-Nucleic Acids

Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics

(2013) G. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective delivery of an anticancer drug with aptamer-functionalized liposomes to breast cancer cells in vitro and in vivo

(2013) Hang Xing et al.   Journal of Materials Chemistry B

Targeted Delivery of Chemotherapy Agents Using a Liver Cancer-Specific Aptamer

(2012) Ling Meng et al.   PLoS One

Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types

(2011) D. Iliopoulos et al.   CANCER RESEARCH

Polymeric Nanoparticles with Precise Ratiometric Control over Drug Loading for Combination Therapy

(2011) Santosh Aryal et al.   MOLECULAR PHARMACEUTICS

Peptide-mediated targeted drug delivery

(2010) Sumit Majumdar et al.   MEDICINAL RESEARCH REVIEWS

Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy

(2010) N. Kolishetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Assembly of an Aptamer-Drug Conjugate for Targeted Drug Delivery to Tumor Cells

(2009) Yu-Fen Huang et al.   CHEMBIOCHEM

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

(2009) Paula J. Bates et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Dose Escalation Methods in Phase I Cancer Clinical Trials

(2009) Christophe Le Tourneau et al.   JNCI-Journal of the National Cancer Institute

Hydrophobically modified glycol chitosan nanoparticles-encapsulated camptothecin enhance the drug stability and tumor targeting in cancer therapy

(2008) Kyung Hyun Min et al.   JOURNAL OF CONTROLLED RELEASE