Moving toward a predictive and personalized clinical approach in amyotrophic lateral sclerosis: novel developments and future directions in diagnosis, genetics, pathogenesis and therapies

Guidelines for preclinical animal research in ALS/MND: A consensus meeting

(2010) Albert C. Ludolph et al.   Amyotrophic Lateral Sclerosis

Current hypotheses for the underlying biology of amyotrophic lateral sclerosis

(2010) Jeffrey D. Rothstein   ANNALS OF NEUROLOGY

Correlation between pyramidal tract degeneration and widespread white matter involvement in amyotrophic lateral sclerosis: A study with tractography and diffusion-tensor imaging

(2009) Joe Senda et al.   Amyotrophic Lateral Sclerosis

The natural history of ALS is changing: Improved survival

(2009) Muddasir Qureshi et al.   Amyotrophic Lateral Sclerosis

MRI-based functional neuroimaging in ALS: An update

(2009) Dorothée Lulé et al.   Amyotrophic Lateral Sclerosis

A phase II trial of talampanel in subjects with amyotrophic lateral sclerosis

(2009) Robert M. Pascuzzi et al.   Amyotrophic Lateral Sclerosis

INSPIRATIonAL – INSPIRAtory muscle training in amyotrophic lateral sclerosis

(2009) Benjamin C. Cheah et al.   Amyotrophic Lateral Sclerosis

ALS in Italian professional soccer players: The risk is still present and could be soccer-specific

(2009) Adriano Chiò et al.   Amyotrophic Lateral Sclerosis

What we truly know about occupation as a risk factor for ALS: A critical and systematic review

(2009) Nadia A. Sutedja et al.   Amyotrophic Lateral Sclerosis

Genetic studies of amyotrophic lateral sclerosis: Controversies and perspectives

(2009) Ana Beleza-Meireles et al.   Amyotrophic Lateral Sclerosis

Smoking and risk for amyotrophic lateral sclerosis: Analysis of the EPIC cohort

(2009) Valentina Gallo et al.   ANNALS OF NEUROLOGY

Mitochondrial dysfunction in amyotrophic lateral sclerosis

(2009) Ping Shi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Stem-cell transplantation into the frontal motor cortex in amyotrophic lateral sclerosis patients

(2009) Hector R. Martinez et al.   CYTOTHERAPY

Mesenchymal stem cell transplantation in amyotrophic lateral sclerosis: A Phase I clinical trial

(2009) L. Mazzini et al.   EXPERIMENTAL NEUROLOGY

Arimoclomol: a potential therapy under development for ALS

(2009) Veena Lanka et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis

(2009) Adriano Chiò et al.   HUMAN MOLECULAR GENETICS

Incidence of amyotrophic lateral sclerosis in Europe

(2009) G. Logroscino et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Low uric acid levels in serum of patients with ALS: Further evidence for oxidative stress?

(2009) D. Keizman et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Do patients with amyotrophic lateral sclerosis (ALS) have increased energy needs?

(2009) Nachum Vaisman et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Modafinil treatment of fatigue in patients with ALS: A placebo-controlled study

(2009) Judith G. Rabkin et al.   MUSCLE & NERVE

Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis

(2009) Michael A van Es et al.   NATURE GENETICS

Genetics of motor neuron disorders: new insights into pathogenic mechanisms

(2009) Patrick A. Dion et al.   NATURE REVIEWS GENETICS

Mutations in FUS cause FALS and SALS in French and French Canadian populations

(2009) V. V. Belzil et al.   NEUROLOGY

Smoking may be considered an established risk factor for sporadic ALS

(2009) C. Armon   NEUROLOGY

Practice Parameter update: The care of the patient with amyotrophic lateral sclerosis: Drug, nutritional, and respiratory therapies (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology

(2009) R. G. Miller et al.   NEUROLOGY

Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis

(2009) J. E. Landers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration

(2009) I. Wegorzewska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromogranin B P413L variant as risk factor and modifier of disease onset for amyotrophic lateral sclerosis

(2009) F. Gros-Louis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

(2009) C. Vance et al.   SCIENCE

Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis

(2009) T. J. Kwiatkowski et al.   SCIENCE

Creatine monohydrate in ALS: Effects on strength, fatigue, respiratory status and ALSFRS

(2008) Jeffrey Rosenfeld et al.   Amyotrophic Lateral Sclerosis

High metabolic level in patients with familial amyotrophic lateral sclerosis

(2008) Benoit Funalot et al.   Amyotrophic Lateral Sclerosis

TDP-43mutation in familial amyotrophic lateral sclerosis

(2008) Akio Yokoseki et al.   ANNALS OF NEUROLOGY

Electrodiagnostic criteria for diagnosis of ALS

(2008) Mamede de Carvalho et al.   CLINICAL NEUROPHYSIOLOGY

KNS-760704 [(6R)-4,5,6,7-tetrahydro-N6-propyl-2, 6-benzothiazole-diamine dihydrochloride monohydrate] for the Treatment of Amyotrophic Lateral Sclerosis

(2008) Valentin K. Gribkoff et al.   CNS Neuroscience & Therapeutics

Mechanism of Ceftriaxone Induction of Excitatory Amino Acid Transporter-2 Expression and Glutamate Uptake in Primary Human Astrocytes

(2008) Seok-Geun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Meta-analysis of vascular endothelial growth factor variations in amyotrophic lateral sclerosis: increased susceptibility in male carriers of the -2578AA genotype

(2008) D Lambrechts et al.   JOURNAL OF MEDICAL GENETICS

Cause of death and clinical grading criteria in a cohort of amyotrophic lateral sclerosis cases undergoing autopsy from the Scottish Motor Neurone Disease Register

(2008) K M Kurian et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Systematic Review of the Effectiveness of Botulinum Toxin or Radiotherapy for Sialorrhea in Patients with Amyotrophic Lateral Sclerosis

(2008) Carol A. Stone et al.   JOURNAL OF PAIN AND SYMPTOM MANAGEMENT

Copy-number variation in sporadic amyotrophic lateral sclerosis: a genome-wide screen

(2008) Hylke M Blauw et al.   LANCET NEUROLOGY

Brain–computer interfaces in neurological rehabilitation

(2008) Janis J Daly et al.   LANCET NEUROLOGY

Arimoclomol at dosages up to 300 mg/day is well tolerated and safe in amyotrophic lateral sclerosis

(2008) Merit E. Cudkowicz et al.   MUSCLE & NERVE

TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

(2008) Edor Kabashi et al.   NATURE GENETICS

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

(2008) Koji Yamanaka et al.   NATURE NEUROSCIENCE

Dyslipidemia is a protective factor in amyotrophic lateral sclerosis

(2008) L. Dupuis et al.   NEUROLOGY

The ALS/PDC syndrome of Guam and the cycad hypothesis

(2008) J. C. Steele et al.   NEUROLOGY

Upper motor neuron and extra-motor neuron involvement in amyotrophic lateral sclerosis: A clinical and brain imaging review

(2008) M.M. van der Graaff et al.   NEUROMUSCULAR DISORDERS

An evaluation of a data mining signal for amyotrophic lateral sclerosis and statins detected in FDA's spontaneous adverse event reporting system

(2008) Eric Colman et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice

(2008) K. Yamanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons

(2008) J. T. Dimos et al.   SCIENCE

TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

(2008) J. Sreedharan et al.   SCIENCE

Complete worldwide operative experience in laparoscopic diaphragm pacing: results and differences in spinal cord injured patients and amyotrophic lateral sclerosis patients

(2008) Raymond P. Onders et al.   SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES

Analysis of survival and prognostic factors in amyotrophic lateral sclerosis: a population based study

(2007) S Zoccolella et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Predictors of long survival in amyotrophic lateral sclerosis: A population-based study

(2007) Stefano Zoccolella et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES