期刊
AMYOTROPHIC LATERAL SCLEROSIS
卷 10, 期 1, 页码 1-14出版社
INFORMA HEALTHCARE
DOI: 10.1080/17482960802585469
关键词
Genetics; association; linkage; genome-wide association; copy number variation
资金
- Motor Neurone Disease Association and the Medical Research Council
- Medical Research Council [G0600974] Funding Source: researchfish
- MRC [G0600974] Funding Source: UKRI
The genetic causes of amyotrophic lateral sclerosis (ALS) are slowly being dissected out with the help of recent advances in genetic technology. Linkage studies and association studies examining candidate genes, candidate pathways, and genome-wide association have been used, based on direct sequencing and correlations between genetic variations. Copy number and microsatellite variants have also been examined, although the ideal methods for analysis are still being developed. In this review we examine the evidence for a genetic basis to ALS, discuss the challenges and difficulties faced and summarize the support for the reported genetic causes of ALS.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据