tmRNA-mediated trans-translation as the major ribosome rescue system in a bacterial cell

Active and Accuratetrans-Translation Requires Distinct Determinants in the C-terminal Tail of SmpB Protein and the mRNA-like Domain of Transfer Messenger RNA (tmRNA)

(2013) Devin Camenares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

YoeB–ribosome structure: a canonical RNase that requires the ribosome for its specific activity

(2013) Shu Feng et al.   NUCLEIC ACIDS RESEARCH

Identification of residues required for stalled-ribosome rescue in the codon-independent release factor YaeJ

(2013) H. Kogure et al.   NUCLEIC ACIDS RESEARCH

tmRNA Is Essential in Shigella flexneri

(2013) Nitya S. Ramadoss et al.   PLoS One

Small molecule inhibitors of trans-translation have broad-spectrum antibiotic activity

(2013) N. S. Ramadoss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution structure and siRNA-mediated knockdown analysis of the mitochondrial disease-related protein C12orf65

(2013) Hiroyuki Kogure et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

An unusual mechanism for EF-Tu activation during tmRNA-mediated ribosome rescue

(2013) M. R. Miller et al.   RNA

ArfA Recruits RF2 into Stalled Ribosomes

(2012) Yoshihiro Shimizu   JOURNAL OF MOLECULAR BIOLOGY

Multisite Ribosomal Stalling: A Unique Mode of Regulatory Nascent Chain Action Revealed for MifM

(2012) Shinobu Chiba et al.   MOLECULAR CELL

ArfA recruits release factor 2 to rescue stalled ribosomes by peptidyl-tRNA hydrolysis inEscherichia coli

(2012) Yuhei Chadani et al.   MOLECULAR MICROBIOLOGY

The complex of tmRNA–SmpB and EF-G on translocating ribosomes

(2012) David J. F. Ramrath et al.   NATURE

EF-P Is Essential for Rapid Synthesis of Proteins Containing Consecutive Proline Residues

(2012) L. K. Doerfel et al.   SCIENCE

Translation Elongation Factor EF-P Alleviates Ribosome Stalling at Polyproline Stretches

(2012) S. Ude et al.   SCIENCE

Structural Basis for the Rescue of Stalled Ribosomes: Structure of YaeJ Bound to the Ribosome

(2012) M. G. Gagnon et al.   SCIENCE

Decoding in the Absence of a Codon by tmRNA and SmpB in the Ribosome

(2012) C. Neubauer et al.   SCIENCE

Dissociation by Pelota, Hbs1 and ABCE1 of mammalian vacant 80S ribosomes and stalled elongation complexes

(2011) Vera P Pisareva et al.   EMBO JOURNAL

trans-translation-mediated tight regulation of the expression of the alternative ribosome-rescue factor ArfA in Escherichia coli

(2011) Yuhei Chadani et al.   GENES & GENETIC SYSTEMS

Acetylation Regulates the Stability of a Bacterial Protein: Growth Stage-Dependent Modification of RNase R

(2011) Wenxing Liang et al.   MOLECULAR CELL

tmRNA regulates synthesis of the ArfA ribosome rescue factor

(2011) Fernando Garza-Sánchez et al.   MOLECULAR MICROBIOLOGY

Escherichia coli YaeJ protein mediates a novel ribosome-rescue pathway distinct from SsrA- and ArfA-mediated pathways

(2011) Yuhei Chadani et al.   MOLECULAR MICROBIOLOGY

Elongation factor 4 (EF4/LepA) accelerates protein synthesis at increased Mg2+ concentrations

(2011) M. Pech et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of SmpB and the ribosomal decoding center in licensing tmRNA entry into stalled ribosomes

(2011) M. R. Miller et al.   RNA

Pyrazinamide Inhibits Trans-Translation in Mycobacterium tuberculosis

(2011) W. Shi et al.   SCIENCE

Visualizing the transfer-messenger RNA as the ribosome resumes translation

(2010) Jie Fu et al.   EMBO JOURNAL

tmRNA–SmpB: a journey to the centre of the bacterial ribosome

(2010) Félix Weis et al.   EMBO JOURNAL

A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome

(2010) Ricarda Richter et al.   EMBO JOURNAL

A Novel Mechanism for Ribonuclease Regulation

(2010) Wenxing Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solution Structure of the Catalytic Domain of the Mitochondrial Protein ICT1 That Is Essential for Cell Vitality

(2010) Yoshihiro Handa et al.   JOURNAL OF MOLECULAR BIOLOGY

Novel factor rescues ribosomes trapped on non-stop mRNAs

(2010) Hyouta Himeno   MOLECULAR MICROBIOLOGY

Non-stop mRNA decay initiates at the ribosome

(2010) Zhiyun Ge et al.   MOLECULAR MICROBIOLOGY

Structure of the Dom34–Hbs1 complex and implications for no-go decay

(2010) Liming Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

YaeJ is a novel ribosome-associated protein in Escherichia coli that can hydrolyze peptidyl-tRNA on stalled ribosomes

(2010) Y. Handa et al.   NUCLEIC ACIDS RESEARCH

Variations on the tmRNA gene

(2010) Chunhong Mao et al.   RNA Biology

Role of the C-terminal tail of SmpB in the early stage of trans-translation

(2010) D. Kurita et al.   RNA

Dom34:Hbs1 Promotes Subunit Dissociation and Peptidyl-tRNA Drop-Off to Initiate No-Go Decay

(2010) C. J. Shoemaker et al.   SCIENCE

A ribosome–nascent chain sensor of membrane protein biogenesis in Bacillus subtilis

(2009) Shinobu Chiba et al.   EMBO JOURNAL

Transfer–messenger RNA controls the translation of cell-cycle and stress proteins in Streptomyces

(2009) Sharief Barends et al.   EMBO REPORTS

Ribosome hijacking: a role for small protein B during trans-translation

(2009) Sylvie Nonin-Lecomte et al.   EMBO REPORTS

Suppression by enhanced RpoE activity of the temperature-sensitive phenotype of a degP ssrA double mutant in Escherichia coli

(2009) Katsuhiko Ono et al.   GENES & GENETIC SYSTEMS

Analysis of nonstop mRNA translation in the absence of tmRNA inEscherichia coli

(2009) Kazushige Kuroha et al.   GENES TO CELLS

Kinetics of Paused Ribosome Recycling in Escherichia coli

(2009) Brian D. Janssen et al.   JOURNAL OF MOLECULAR BIOLOGY

tmRNA·SmpB complex mimics native aminoacyl-tRNAs in the A site of stalled ribosomes

(2009) Kimberley Cheng et al.   JOURNAL OF STRUCTURAL BIOLOGY

Co-evolution of multipartite interactions between an extended tmRNA tag and a robust Lon protease inMycoplasma

(2009) Zhiyun Ge et al.   MOLECULAR MICROBIOLOGY

RNase II is important for A-site mRNA cleavage during ribosome pausing

(2009) Fernando Garza-Sánchez et al.   MOLECULAR MICROBIOLOGY

Accommodation of tmRNA-SmpB into stalled ribosomes: A cryo-EM study

(2009) F. Weis et al.   RNA

Formation of the First Peptide Bond: The Structure of EF-P Bound to the 70S Ribosome

(2009) G. Blaha et al.   SCIENCE

Biology oftrans-Translation

(2008) Kenneth C. Keiler   Annual Review of Microbiology

Trans-Translation is Involved in the CcpA-Dependent Tagging and Degradation of TreP in Bacillus subtilis

(2008) H. Ujiie et al.   JOURNAL OF BIOCHEMISTRY

Recycling of Ribosomal Complexes Stalled at the Step of Elongation in Escherichia coli

(2008) Nongmaithem Sadananda Singh et al.   JOURNAL OF MOLECULAR BIOLOGY

Recycling of Aborted Ribosomal 50S Subunit-Nascent Chain-tRNA Complexes by the Heat Shock Protein Hsp15

(2008) Linhua Jiang et al.   JOURNAL OF MOLECULAR BIOLOGY

Cleavage of mRNAs and role of tmRNA system under amino acid starvation in Escherichia coli

(2008) Xia Li et al.   MOLECULAR MICROBIOLOGY

tmRNA-dependenttrans-translation is required for sporulation inBacillus subtilis

(2008) Teppei Abe et al.   MOLECULAR MICROBIOLOGY

Trans-Translation in Helicobacter pylori: Essentiality of Ribosome Rescue and Requirement of Protein Tagging for Stress Resistance and Competence

(2008) Marie Thibonnier et al.   PLoS One

Evolution of the ssrA degradation tag in Mycoplasma: Specificity switch to a different protease

(2008) E. Gur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA