PIWI proteins and their interactors in piRNA biogenesis, germline development and gene expression

Visiting “Noncodarnia”

(2016) Jeffrey M. Perkel   BIOTECHNIQUES

PIWI proteins and PIWI-interacting RNAs in the soma

(2014) Robert J. Ross et al.   NATURE

PIWI proteins are essential for early Drosophila embryogenesis

(2013) Sneha Ramesh Mani et al.   DEVELOPMENTAL BIOLOGY

Analysis of Hydra PIWI proteins and piRNAs uncover early evolutionary origins of the piRNA pathway

(2013) Robyn S.M. Lim et al.   DEVELOPMENTAL BIOLOGY

A Major Epigenetic Programming Mechanism Guided by piRNAs

(2013) Xiao A. Huang et al.   DEVELOPMENTAL CELL

Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline

(2013) Jonathan P Saxe et al.   EMBO JOURNAL

Deep sequencing of small RNA transcriptome reveals novel non-coding RNAs in hepatocellular carcinoma

(2013) Priscilla T.-Y. Law et al.   JOURNAL OF HEPATOLOGY

PIWI-interacting RNAs: from generation to transgenerational epigenetics

(2013) Maartje J. Luteijn et al.   NATURE REVIEWS GENETICS

PIWI proteins and PIWI-interacting RNAs function in Hydra somatic stem cells

(2013) C. E. Juliano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Function of Piwi, a nuclear Piwi/Argonaute protein, is independent of its slicer activity

(2013) Nicole Darricarrère et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice

(2013) R. R. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Silencing of Transposons by Piwi and Maelstrom and Its Impact on Chromatin State and Gene Expression

(2012) Grzegorz Sienski et al.   CELL

A Role for Neuronal piRNAs in the Epigenetic Control of Memory-Related Synaptic Plasticity

(2012) Priyamvada Rajasethupathy et al.   CELL

piRNAs Can Trigger a Multigenerational Epigenetic Memory in the Germline of C. elegans

(2012) Alyson Ashe et al.   CELL

piRNAs Initiate an Epigenetic Memory of Nonself RNA in the C. elegans Germline

(2012) Masaki Shirayama et al.   CELL

Altered expression of piRNAs and their relation with clinicopathologic features of breast cancer

(2012) G. Huang et al.   Clinical & Translational Oncology

Tudor domain proteins in development

(2012) J. W. Pek et al.   DEVELOPMENT

piRNA-mediated transgenerational inheritance of an acquired trait

(2012) T. Grentzinger et al.   GENOME RESEARCH

The Cochaperone Shutdown Defines a Group of Biogenesis Factors Essential for All piRNA Populations in Drosophila

(2012) Daniel Olivieri et al.   MOLECULAR CELL

A Role for Fkbp6 and the Chaperone Machinery in piRNA Amplification and Transposon Silencing

(2012) Jordi Xiol et al.   MOLECULAR CELL

Structure and function of Zucchini endoribonuclease in piRNA biogenesis

(2012) Hiroshi Nishimasu et al.   NATURE

Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis

(2012) Anastassios Vourekas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

shutdown is a component of the Drosophila piRNA biogenesis machinery

(2012) J. B. Preall et al.   RNA

Uniting Germline and Stem Cells: The Function of Piwi Proteins and the piRNA Pathway in Diverse Organisms

(2011) Celina Juliano et al.   Annual Review of Genetics

piRNA, the new non-coding RNA, is aberrantly expressed in human cancer cells

(2011) Jia Cheng et al.   CLINICA CHIMICA ACTA

piRNA Production Requires Heterochromatin Formation in Drosophila

(2011) Prashanth Rangan et al.   CURRENT BIOLOGY

Vreteno, a gonad-specific protein, is essential for germline development and primary piRNA biogenesis in Drosophila

(2011) A. L. Zamparini et al.   DEVELOPMENT

PAPI, a novel TUDOR-domain protein, complexes with AGO3, ME31B and TRAL in the nuage to silence transposition

(2011) L. Liu et al.   DEVELOPMENT

MITOPLD Is a Mitochondrial Protein Essential for Nuage Formation and piRNA Biogenesis in the Mouse Germline

(2011) Toshiaki Watanabe et al.   DEVELOPMENTAL CELL

piRNA-Associated Germline Nuage Formation and Spermatogenesis Require MitoPLD Profusogenic Mitochondrial-Surface Lipid Signaling

(2011) Huiyan Huang et al.   DEVELOPMENTAL CELL

The tudor domain protein Kumo is required to assemble the nuage and to generate germline piRNAs inDrosophila

(2011) Amit Anand et al.   EMBO JOURNAL

The Cutoff protein regulates piRNA cluster expression and piRNA production in theDrosophilagermline

(2011) Attilio Pane et al.   EMBO JOURNAL

A systematic analysis ofDrosophilaTUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors

(2011) Dominik Handler et al.   EMBO JOURNAL

Maelstrom coordinates microtubule organization during Drosophila oogenesis through interaction with components of the MTOC

(2011) K. Sato et al.   GENES & DEVELOPMENT

TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice

(2011) Yukihiro Yabuta et al.   JOURNAL OF CELL BIOLOGY

3′ End Formation of PIWI-Interacting RNAs In Vitro

(2011) Shinpei Kawaoka et al.   MOLECULAR CELL

Heterotypic piRNA Ping-Pong Requires Qin, a Protein with Both E3 Ligase and Tudor Domains

(2011) Zhao Zhang et al.   MOLECULAR CELL

Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing

(2011) Michael Reuter et al.   NATURE

Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis

(2011) T. Tanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of piRNAs in the central nervous system

(2011) E. J. Lee et al.   RNA

Role for piRNAs and Noncoding RNA in de Novo DNA Methylation of the Imprinted Mouse Rasgrf1 Locus

(2011) T. Watanabe et al.   SCIENCE

Gender-Specific Hierarchy in Nuage Localization of PIWI-Interacting RNA Factors in Drosophila

(2011) Akihiro Nagao et al.   Frontiers in Genetics

Expression of the Argonaute protein PiwiL2 and piRNAs in adult mouse mesenchymal stem cells

(2010) Qiuling Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Repression of Retroelements in Drosophila Germline via piRNA Pathway by the Tudor Domain Protein Tejas

(2010) Veena S. Patil et al.   CURRENT BIOLOGY

An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila

(2010) Daniel Olivieri et al.   EMBO JOURNAL

How does the Royal Family of Tudor rule the PIWI-interacting RNA pathway?

(2010) M. C. Siomi et al.   GENES & DEVELOPMENT

Probing the initiation and effector phases of the somatic piRNA pathway in Drosophila

(2010) A. D. Haase et al.   GENES & DEVELOPMENT

Roles for the Yb body components Armitage and Yb in primary piRNA biogenesis in Drosophila

(2010) K. Saito et al.   GENES & DEVELOPMENT

Arginine Methylation of Vasa Protein Is Conserved across Phyla

(2010) Yohei Kirino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Yb Body, a Major Site for Piwi-associated RNA Biogenesis and a Gateway for Piwi Expression and Transport to the Nucleus in Somatic Cells

(2010) Hongying Qi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo

(2010) Christel Rouget et al.   NATURE

Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons

(2010) Valeria Specchia et al.   NATURE

Drosophila Piwi functions in Hsp90-mediated suppression of phenotypic variation

(2010) Vamsi K Gangaraju et al.   NATURE GENETICS

Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain

(2010) K. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway

(2010) K. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs

(2010) R. J. A. Frost et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ectopic Expression of Germline Genes Drives Malignant Brain Tumor Growth in Drosophila

(2010) A. Janic et al.   SCIENCE

The Biogenesis and Function of PIWI Proteins and piRNAs: Progress and Prospect

(2009) Travis Thomson et al.   Annual Review of Cell and Developmental Biology

Specialized piRNA Pathways Act in Germline and Somatic Tissues of the Drosophila Ovary

(2009) Colin D. Malone et al.   CELL

Collapse of Germline piRNAs in the Absence of Argonaute3 Reveals Somatic piRNAs in Flies

(2009) Chengjian Li et al.   CELL

The Drosophila HP1 Homolog Rhino Is Required for Transposon Silencing and piRNA Production by Dual-Strand Clusters

(2009) Carla Klattenhoff et al.   CELL

Mili Interacts with Tudor Domain-Containing Protein 1 in Regulating Spermatogenesis

(2009) Jianquan Wang et al.   CURRENT BIOLOGY

A Broadly Conserved Pathway Generates 3′UTR-Directed Primary piRNAs

(2009) Nicolas Robine et al.   CURRENT BIOLOGY

Tdrd6 Is Required for Spermiogenesis, Chromatoid Body Architecture, and Regulation of miRNA Expression

(2009) Ana Vasileva et al.   CURRENT BIOLOGY

The TDRD9-MIWI2 Complex Is Essential for piRNA-Mediated Retrotransposon Silencing in the Mouse Male Germline

(2009) Masanobu Shoji et al.   DEVELOPMENTAL CELL

Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines

(2009) Kazumichi M Nishida et al.   EMBO JOURNAL

Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members

(2009) V. V. Vagin et al.   GENES & DEVELOPMENT

piRNAs mediate posttranscriptional retroelement silencing and localization to pi-bodies in theDrosophilagermline

(2009) Ai Khim Lim et al.   JOURNAL OF CELL BIOLOGY

A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila

(2009) Kuniaki Saito et al.   NATURE

A three-dimensional view of the molecular machinery of RNA interference

(2009) Martin Jinek et al.   NATURE

Loss of the Mili-interacting Tudor domain–containing protein-1 activates transposons and alters the Mili-associated small RNA profile

(2009) Michael Reuter et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi

(2009) C. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-resolution profiling and discovery of planarian small RNAs

(2009) Marc R. Friedländer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization

(2009) Y. Kirino et al.   RNA

Two Piwi proteins, Xiwi and Xili, are expressed in the Xenopus female germline

(2009) A. Wilczynska et al.   RNA

Cytoplasmic Compartmentalization of the Fetal piRNA Pathway in Mice

(2009) Alexei A. Aravin et al.   PLoS Genetics

A C. elegans Piwi, PRG-1, Regulates 21U-RNAs during Spermatogenesis

(2008) Guilin Wang et al.   CURRENT BIOLOGY

Zili is required for germ cell differentiation and meiosis in zebrafish

(2008) Saskia Houwing et al.   EMBO JOURNAL

DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

(2008) S. Kuramochi-Miyagawa et al.   GENES & DEVELOPMENT

MILI, a PIWI-interacting RNA-binding Protein, Is Required for Germ Line Stem Cell Self-renewal and Appears to Positively Regulate Translation

(2008) Yingdee Unhavaithaya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isolation of new polar granule components in Drosophila reveals P body and ER associated proteins

(2008) Travis Thomson et al.   MECHANISMS OF DEVELOPMENT

A piRNA Pathway Primed by Individual Transposons Is Linked to De Novo DNA Methylation in Mice

(2008) Alexei A. Aravin et al.   MOLECULAR CELL

PRG-1 and 21U-RNAs Interact to Form the piRNA Complex Required for Fertility in C. elegans

(2008) Pedro J. Batista et al.   MOLECULAR CELL

The PIWI proteins SMEDWI-2 and SMEDWI-3 are required for stem cell function and piRNA expression in planarians

(2008) D. Palakodeti et al.   RNA

An Epigenetic Role for Maternally Inherited piRNAs in Transposon Silencing

(2008) J. Brennecke et al.   SCIENCE

Conserved themes in small-RNA-mediated transposon control

(2008) Angélique Girard et al.   TRENDS IN CELL BIOLOGY