Gastric cancer cells inhibit natural killer cell proliferation and induce apoptosis via prostaglandin E2

Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection

(2015) Jonathan H Chen et al.   NATURE MEDICINE

Natural killers: Cataloging immune cells for immunotherapy

(2015) Amanda B. Keener   NATURE MEDICINE

The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014

(2014) R. Salgado et al.   ANNALS OF ONCOLOGY

Inhibition of Tumor-Derived Prostaglandin-E2 Blocks the Induction of Myeloid-Derived Suppressor Cells and Recovers Natural Killer Cell Activity

(2014) Y. Mao et al.   CLINICAL CANCER RESEARCH

Aspirin and COX-2 Inhibitor Use in Patients With Stage III Colon Cancer

(2014) Kimmie Ng et al.   JNCI-Journal of the National Cancer Institute

Cancer-related inflammation and treatment effectiveness

(2014) Connie I Diakos et al.   LANCET ONCOLOGY

Genetics of gastric cancer

(2014) Mairi H. McLean et al.   Nature Reviews Gastroenterology & Hepatology

COX-2 Inhibition Potentiates Antiangiogenic Cancer Therapy and Prevents Metastasis in Preclinical Models

(2014) L. Xu et al.   Science Translational Medicine

RORγt+ Innate Lymphoid Cells Acquire a Proinflammatory Program upon Engagement of the Activating Receptor NKp44

(2013) Timor Glatzer et al.   IMMUNITY

Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity

(2012) G. Pietra et al.   CANCER RESEARCH

CD8+ T Cells That Produce Interleukin-17 Regulate Myeloid-Derived Suppressor Cells and Are Associated With Survival Time of Patients With Gastric Cancer

(2012) Yuan Zhuang et al.   GASTROENTEROLOGY

Monocyte/macrophage-elicited natural killer cell dysfunction in hepatocellular carcinoma is mediated by CD48/2B4 interactions

(2012) Yan Wu et al.   HEPATOLOGY

Tuning of Natural Killer Cell Reactivity by NKp46 and Helios Calibrates T Cell Responses

(2012) E. Narni-Mancinelli et al.   SCIENCE

Trial watch

(2012) Laura Senovilla et al.   OncoImmunology

Natural Innate and Adaptive Immunity to Cancer

(2011) Matthew D. Vesely et al.   Annual Review of Immunology

Prostaglandin E2 EP receptors as therapeutic targets in breast cancer

(2011) Jocelyn Reader et al.   CANCER AND METASTASIS REVIEWS

Hepatocellular carcinoma-associated fibroblasts trigger NK cell dysfunction via PGE2 and IDO

(2011) Tuanjie Li et al.   CANCER LETTERS

Adoptive Transfer of Autologous Natural Killer Cells Leads to High Levels of Circulating Natural Killer Cells but Does Not Mediate Tumor Regression

(2011) M. R. Parkhurst et al.   CLINICAL CANCER RESEARCH

Regulation of Immune Responses by Prostaglandin E2

(2011) P. Kalinski   JOURNAL OF IMMUNOLOGY

Neutrophils promote motility of cancer cells via a hyaluronan-mediated TLR4/PI3K activation loop

(2011) Yan Wu et al.   JOURNAL OF PATHOLOGY

Innate or Adaptive Immunity? The Example of Natural Killer Cells

(2011) E. Vivier et al.   SCIENCE

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Editorial: PGE2-producing MDSC: a role in tumor progression?

(2010) Paolo Serafini   JOURNAL OF LEUKOCYTE BIOLOGY

Pivotal Advance: Tumor-mediated induction of myeloid-derived suppressor cells and M2-polarized macrophages by altering intracellular PGE2 catabolism in myeloid cells

(2010) Evgeniy Eruslanov et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cyclooxygenase-2 in Cancer and Angiogenesis

(2008) Mehmet Şahin et al.   ANGIOLOGY

Antagonism of the prostaglandin E receptor EP4 inhibits metastasis and enhances NK function

(2008) Namita Kundu et al.   BREAST CANCER RESEARCH AND TREATMENT

Tumour immunity: effector response to tumour and role of the microenvironment

(2008) Alberto Mantovani et al.   LANCET