Autophagy as a Possible Underlying Mechanism of Nanomaterial Toxicity

Autophagic proteins regulate cigarette smoke induced apoptosis: Protective role of heme oxygenase-1

(2014) Hong Pyo Kim et al.   Autophagy

Cytotoxicity, oxidative stress, apoptosis and the autophagic effects of silver nanoparticles in mouse embryonic fibroblasts

(2014) Yu-Hsuan Lee et al.   BIOMATERIALS

Short-term inhalation of cadmium oxide nanoparticles alters pulmonary dynamics associated with lung injury, inflammation, and repair in a mouse model

(2014) Jason L. Blum et al.   INHALATION TOXICOLOGY

Nanotoxicity: Oxidative Stress Mediated Toxicity of Metal and Metal Oxide Nanoparticles

(2014) Abhijit Sarkar et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Structure and Functional Properties of a Multimeric Protein αA-Crystallin Adsorbed on Silver Nanoparticle Surface

(2014) Victor Banerjee et al.   LANGMUIR

Toxicity of carboxylated carbon nanotubes in endothelial cells is attenuated by stimulation of the autophagic flux with the release of nanomaterial in autophagic vesicles

(2014) Martina Orecna et al.   Nanomedicine-Nanotechnology Biology and Medicine

Nickel Nanoparticles cause exaggerated lung and airway remodeling in mice lacking the T-box transcription factor, TBX21 (T-bet)

(2014) Ellen E Glista-Baker et al.   Particle and Fibre Toxicology

Equivalent titanium dioxide nanoparticle deposition by intratracheal instillation and whole body inhalation: the effect of dose rate on acute respiratory tract inflammation

(2014) Brittany L Baisch et al.   Particle and Fibre Toxicology

Physicochemical characteristics of nanomaterials that affect pulmonary inflammation

(2014) Hedwig M Braakhuis et al.   Particle and Fibre Toxicology

Zinc oxide nanoparticles induce apoptosis by enhancement of autophagy via PI3K/Akt/mTOR inhibition

(2014) Ruchi Roy et al.   TOXICOLOGY LETTERS

Application of vitamin E to antagonize SWCNTs-induced exacerbation of allergic asthma

(2014) Jinquan Li et al.   Scientific Reports

Actin Reorganization through Dynamic Interactions with Single-Wall Carbon Nanotubes

(2013) Hengameh Shams et al.   ACS Nano

Impact of Protein Modification on the Protein Corona on Nanoparticles and Nanoparticle–Cell Interactions

(2013) Lennart Treuel et al.   ACS Nano

Pulmonary toxicity of carbon nanotubes and asbestos — Similarities and differences

(2013) Ken Donaldson et al.   ADVANCED DRUG DELIVERY REVIEWS

New Insights into Understanding the Mechanisms, Pathogenesis, and Management of Malignant Mesotheliomas

(2013) Brooke T. Mossman et al.   AMERICAN JOURNAL OF PATHOLOGY

Dual Acute Proinflammatory and Antifibrotic Pulmonary Effects of Short Palate, Lung, and Nasal Epithelium Clone–1 after Exposure to Carbon Nanotubes

(2013) Y. Peter Di et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Genotoxic and carcinogenic potential of engineered nanoparticles: an update

(2013) Ashutosh Kumar et al.   ARCHIVES OF TOXICOLOGY

ERK pathway is activated in bare-FeNPs-induced autophagy

(2013) Eun-Jung Park et al.   ARCHIVES OF TOXICOLOGY

Highly purified, multi-wall carbon nanotubes induce light-chain 3B expression in human lung cells

(2013) Tamotsu Tsukahara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Toxicity of commercially available engineered nanoparticles to Caco-2 and SW480 human intestinal epithelial cells

(2013) Talia E. Abbott Chalew et al.   CELL BIOLOGY AND TOXICOLOGY

Inhalation exposure of nano-scaled titanium dioxide (TiO2) particles alters the inflammatory responses in asthmatic mice

(2013) Sofia Jonasson et al.   INHALATION TOXICOLOGY

In vitro study on the alterations of brain tubulin structure and assembly affected by magnetite nanoparticles

(2013) Ali Dadras et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Unprecedented inhibition of tubulin polymerization directed by gold nanoparticles inducing cell cycle arrest and apoptosis

(2013) Diptiman Choudhury et al.   Nanoscale

Intracellular fate of carbon nanotubes inside murine macrophages: pH-dependent detachment of iron catalyst nanoparticles

(2013) Cyrill Bussy et al.   Particle and Fibre Toxicology

Silver Nanoparticle Protein Corona Composition in Cell Culture Media

(2013) Jonathan H. Shannahan et al.   PLoS One

Elucidation of Toxicity Pathways in Lung Epithelial Cells Induced by Silicon Dioxide Nanoparticles

(2013) Odu Okoturo-Evans et al.   PLoS One

Single-walled carbon nanotubes and graphene oxides induce autophagosome accumulation and lysosome impairment in primarily cultured murine peritoneal macrophages

(2013) Bin Wan et al.   TOXICOLOGY LETTERS

Inflammation and gene expression in the rat lung after instillation of silica nanoparticles: Effect of size, dispersion medium and particle surface charge

(2013) David M. Brown et al.   TOXICOLOGY LETTERS

Silica nanoparticle uptake induces survival mechanism in A549 cells by the activation of autophagy but not apoptosis

(2013) Jakub Stanislaw Nowak et al.   TOXICOLOGY LETTERS

Long-term Pulmonary Responses to Quadweekly Intermittent Intratracheal Spray Instillations of Magnetite (Fe3O4) Nanoparticles for 52 Weeks in Fischer 344 Rats

(2013) Yukie Tada et al.   Journal of Toxicologic Pathology

Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle

(2013) Shruti R Saptarshi et al.   JOURNAL OF NANOBIOTECHNOLOGY

Occupational Nanosafety Considerations for Carbon Nanotubes and Carbon Nanofibers

(2012) Vincent Castranova et al.   ACCOUNTS OF CHEMICAL RESEARCH

Titanium Dioxide Nanoparticles Induce Matrix Metalloprotease 1 in Human Pulmonary Fibroblasts Partly via an Interleukin-1β–Dependent Mechanism

(2012) Lucie Armand et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Zinc oxide nanoparticles induce oxidative DNA damage and ROS-triggered mitochondria mediated apoptosis in human liver cells (HepG2)

(2012) Vyom Sharma et al.   APOPTOSIS

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Simultaneous induction of autophagy and toll-like receptor signaling pathways by graphene oxide

(2012) Guan-Yu Chen et al.   BIOMATERIALS

KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma

(2012) Jianhua Ling et al.   CANCER CELL

Multi-walled carbon nanotubes translocate into the pleural cavity and induce visceral mesothelial proliferation in rats

(2012) Jiegou Xu et al.   CANCER SCIENCE

The Emerging Importance of Autophagy in Pulmonary Diseases

(2012) Kenji Mizumura et al.   CHEST

Impact of emerging pollutants on pulmonary inflammation in asthmatic rats: ethanol vapors and agglomerated TiO2nanoparticles

(2012) A. Scarino et al.   INHALATION TOXICOLOGY

Investigating the relationship between nanomaterial hazard and physicochemical properties: Informing the exploitation of nanomaterials within therapeutic and diagnostic applications

(2012) Helinor Johnston et al.   JOURNAL OF CONTROLLED RELEASE

The Interaction of Serum Proteins with Carbon Nanotubes Depend on the Physicochemical Properties of Nanotubes

(2012) Jiangfeng Du et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Evidence for Charge-Transfer-Induced Conformational Changes in Carbon Nanostructure–Protein Corona

(2012) R. Podila et al.   Journal of Physical Chemistry C

DNA damage induced by micro- and nanoparticles--interaction with FPG influences the detection of DNA oxidation in the comet assay

(2012) J. Kain et al.   MUTAGENESIS

Comparative study of ZnO and TiO2nanoparticles: physicochemical characterisation and toxicological effects on human colon carcinoma cells

(2012) Isabella De Angelis et al.   Nanotoxicology

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

(2012) Chong-Shan Shi et al.   NATURE IMMUNOLOGY

Multi-walled carbon nanotubes induce COX-2 and iNOS expression via MAP Kinase-dependent and -independent mechanisms in mouse RAW264.7 macrophages

(2012) Jong Lee et al.   Particle and Fibre Toxicology

Critical role of surface chemical modifications induced by length shortening on multi-walled carbon nanotubes-induced toxicity

(2012) Cyrill Bussy et al.   Particle and Fibre Toxicology

The mechanism of pleural inflammation by long carbon nanotubes: interaction of long fibres with macrophages stimulates them to amplify pro-inflammatory responses in mesothelial cells

(2012) Fiona A Murphy et al.   Particle and Fibre Toxicology

Copper Oxide Nanoparticles Induce Autophagic Cell Death in A549 Cells

(2012) Tingting Sun et al.   PLoS One

Acidic Nanoparticles Are Trafficked to Lysosomes and Restore an Acidic Lysosomal pH and Degradative Function to Compromised ARPE-19 Cells

(2012) Gabriel C. Baltazar et al.   PLoS One

Autophagy induction by silver nanowires: A new aspect in the biocompatibility assessment of nanocomposite thin films

(2012) Navin K. Verma et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mechanisms of carbon nanotube-induced toxicity: Focus on oxidative stress

(2012) Anna A. Shvedova et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

In vitro cytotoxicity and genotoxicity studies of titanium dioxide (TiO2) nanoparticles in Chinese hamster lung fibroblast cells

(2012) Mahsa Hamzeh et al.   TOXICOLOGY IN VITRO

Effects of inhaled nano-TiO2 aerosols showing two distinct agglomeration states on rat lungs

(2012) A. Noël et al.   TOXICOLOGY LETTERS

p62: a versatile multitasker takes on cancer

(2012) Jorge Moscat et al.   TRENDS IN BIOCHEMICAL SCIENCES

Acute Phase Pulmonary Responses to a Single Intratracheal Spray Instillation of Magnetite (Fe3O4) Nanoparticles in Fischer 344 Rats

(2012) Yukie Tada et al.   Journal of Toxicologic Pathology

Bile Pigments in Pulmonary and Vascular Disease

(2012) Stefan W. Ryter   Frontiers in Pharmacology

In Vitro Polymerization of Microtubules with a Fullerene Derivative

(2011) Tatsiana A. Ratnikova et al.   ACS Nano

Amino-Functionalized Polystyrene Nanoparticles Activate the NLRP3 Inflammasome in Human Macrophages

(2011) Oleg Lunov et al.   ACS Nano

Gold Nanoparticles Induce Autophagosome Accumulation through Size-Dependent Nanoparticle Uptake and Lysosome Impairment

(2011) Xiaowei Ma et al.   ACS Nano

Length-Dependent Retention of Carbon Nanotubes in the Pleural Space of Mice Initiates Sustained Inflammation and Progressive Fibrosis on the Parietal Pleura

(2011) Fiona A. Murphy et al.   AMERICAN JOURNAL OF PATHOLOGY

Autophagy

(2011) Jeffrey A. Haspel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Autophagy in Pulmonary Diseases

(2011) Stefan W. Ryter et al.   Annual Review of Physiology

Autophagy stimulation by rapamycin suppresses lung inflammation and infection byBurkholderia cenocepaciain a model of cystic fibrosis

(2011) Basant A. Abdulrahman et al.   Autophagy

Induction of ROS, mitochondrial damage and autophagy in lung epithelial cancer cells by iron oxide nanoparticles

(2011) Mohd Imran Khan et al.   BIOMATERIALS

Autophagy-deficient mice develop multiple liver tumors

(2011) A. Takamura et al.   GENES & DEVELOPMENT

Drug delivery by polymeric nanoparticles induces autophagy in macrophages

(2011) H. Eidi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Mitophagy Plays an Essential Role in Reducing Mitochondrial Production of Reactive Oxygen Species and Mutation of Mitochondrial DNA by Maintaining Mitochondrial Quantity and Quality in Yeast

(2011) Yusuke Kurihara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation

(2011) James Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of C60 Fullerene with the Proteins Involved in DNA Mismatch Repair Pathway

(2011) Shishir Kumar Gupta et al.   Journal of Biomedical Nanotechnology

C60-Fullerene Binds with the ATP Binding Domain of Human DNA Topoiosmerase II Alpha

(2011) Lokesh Baweja et al.   Journal of Biomedical Nanotechnology

Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex

(2011) M. Renna et al.   JOURNAL OF CELL SCIENCE

Interactions between Al12X (X = Al, C, N and P) nanoparticles and DNA nucleobases/base pairs: implications for nanotoxicity

(2011) Peng Jin et al.   JOURNAL OF MOLECULAR MODELING

Cytotoxic and genotoxic effects of multi-wall carbon nanotubes on human umbilical vein endothelial cells in vitro

(2011) Yuan-Yuan Guo et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Quantum dot 705, a cadmium-based nanoparticle, induces persistent inflammation and granuloma formation in the mouse lung

(2011) Chia-Chi Ho et al.   Nanotoxicology

Titanium dioxide nanoparticles exhibit genotoxicity and impair DNA repair activity in A549 cells

(2011) Mary-Line Jugan et al.   Nanotoxicology

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes

(2011) Robert R Mercer et al.   Particle and Fibre Toxicology

Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes

(2011) Hiromi Nabeshi et al.   Particle and Fibre Toxicology

Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes

(2011) Wan-Seob Cho et al.   Particle and Fibre Toxicology

Binding of blood proteins to carbon nanotubes reduces cytotoxicity

(2011) C. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanotoxicology—A Pathologist’s Perspective

(2011) Ann F. Hubbs et al.   TOXICOLOGIC PATHOLOGY

Toxicity and interaction of titanium dioxide nanoparticles with microtubule protein

(2010) Z. N. Gheshlaghi et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Autophagic Protein LC3B Confers Resistance against Hypoxia-induced Pulmonary Hypertension

(2010) Seon-Jin Lee et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cigarette smoke-induced autophagy is regulated by SIRT1–PARP-1-dependent mechanism: Implication in pathogenesis of COPD

(2010) Jae-woong Hwang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Cytotoxicity and genotoxicity of silver nanoparticles in the human lung cancer cell line, A549

(2010) Rasmus Foldbjerg et al.   ARCHIVES OF TOXICOLOGY

DNA binding and aggregation by carbon nanoparticles

(2010) Hongjie An et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy and oxidative stress associated with gold nanoparticles

(2010) Jasmine J. Li et al.   BIOMATERIALS

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation

(2010) Dale W. Hailey et al.   CELL

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

(2010) Joo-Yong Lee et al.   EMBO JOURNAL

Nanosized titanium dioxide particles do not induce DNA damage in human peripheral blood lymphocytes

(2010) Stephan Hackenberg et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Regulation of autophagy by phosphatidylinositol 3-phosphate

(2010) Chloe Burman et al.   FEBS LETTERS

Genetic variation in the autophagy gene ULK1 and risk of Crohnʼs disease

(2010) Liesbet Henckaerts et al.   INFLAMMATORY BOWEL DISEASES

Toxic effects of iron oxide nanoparticles on human umbilical vein endothelial cells

(2010) Wu et al.   International Journal of Nanomedicine

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of an Autophagy Defect in Smokers' Alveolar Macrophages

(2010) M. M. Monick et al.   JOURNAL OF IMMUNOLOGY

Post-Golgi Sec Proteins Are Required for Autophagy in Saccharomyces cerevisiae

(2010) Jiefei Geng et al.   MOLECULAR BIOLOGY OF THE CELL

Possible genotoxic mechanisms of nanoparticles: Criteria for improved test strategies

(2010) Ken Donaldson et al.   Nanotoxicology

DNA damage and alterations in expression of DNA damage responsive genes induced by TiO2nanoparticles in human hepatoma HepG2 cells

(2010) Jana PetkoviĆ et al.   Nanotoxicology

Gold nanoparticles cellular toxicity and recovery: Effect of size, concentration and exposure time

(2010) Tatsiana Mironava et al.   Nanotoxicology

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Plasma membrane contributes to the formation of pre-autophagosomal structures

(2010) Brinda Ravikumar et al.   NATURE CELL BIOLOGY

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

(2010) Alessandro Luciani et al.   NATURE CELL BIOLOGY

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Particle length-dependent titanium dioxide nanomaterials toxicity and bioactivity

(2010) Raymond F Hamilton et al.   Particle and Fibre Toxicology

Asbestos, carbon nanotubes and the pleural mesothelium: a review and the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma

(2010) Ken Donaldson et al.   Particle and Fibre Toxicology

Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells

(2010) Sourav Bhattacharjee et al.   Particle and Fibre Toxicology

Carbon black and titanium dioxide nanoparticles elicit distinct apoptotic pathways in bronchial epithelial cells

(2010) Salik Hussain et al.   Particle and Fibre Toxicology

Nanomaterial cytotoxicity is composition, size, and cell type dependent

(2010) Syed K Sohaebuddin et al.   Particle and Fibre Toxicology

Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema

(2010) Z.-H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High Intracellular Iron Oxide Nanoparticle Concentrations Affect Cellular Cytoskeleton and Focal Adhesion Kinase-Mediated Signaling

(2010) Stefaan J. H. Soenen et al.   Small

Inflammatory responses may be induced by a single intratracheal instillation of iron nanoparticles in mice

(2010) Eun-Jung Park et al.   TOXICOLOGY

Carbon nanotubes induce inflammation but decrease the production of reactive oxygen species in lung

(2010) D. Crouzier et al.   TOXICOLOGY

Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction

(2010) Denise N. Johnson-Lyles et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Silver nanoparticles: Evaluation of DNA damage, toxicity and functional impairment in human mesenchymal stem cells

(2010) Stephan Hackenberg et al.   TOXICOLOGY LETTERS

Bacterial Lipopolysaccharide Enhances PDGF Signaling and Pulmonary Fibrosis in Rats Exposed to Carbon Nanotubes

(2009) Mark F. Cesta et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

3D tomography reveals connections between the phagophore and endoplasmic reticulum

(2009) Päivi Ylä-Anttila et al.   Autophagy

Multiple roles of the cytoskeleton in autophagy

(2009) Iryna Monastyrska et al.   BIOLOGICAL REVIEWS

Cationic Poly(amidoamine) Dendrimer Induces Lysosomal Apoptotic Pathway at Therapeutically Relevant Concentrations

(2009) Thommey P. Thomas et al.   BIOMACROMOLECULES

Titanium Dioxide Nanoparticles Induce DNA Damage and Genetic Instability In vivo in Mice

(2009) B. Trouiller et al.   CANCER RESEARCH

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL

Superoxide is the major reactive oxygen species regulating autophagy

(2009) Y Chen et al.   CELL DEATH AND DIFFERENTIATION

Size dependence of the translocation of inhaled iridium and carbon nanoparticle aggregates from the lung of rats to the blood and secondary target organs

(2009) Wolfgang G. Kreyling et al.   INHALATION TOXICOLOGY

How do ESCRT proteins control autophagy?

(2009) T. E. Rusten et al.   JOURNAL OF CELL SCIENCE

Comparative study of the cytotoxic and genotoxic effects of titanium oxide and aluminium oxide nanoparticles in Chinese hamster ovary (CHO-K1) cells

(2009) A.L. Di Virgilio et al.   JOURNAL OF HAZARDOUS MATERIALS

Functionalized Carbon Nanotubes Specifically Bind to α-Chymotrypsin’s Catalytic Site and Regulate Its Enzymatic Function

(2009) Bin Zhang et al.   NANO LETTERS

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

(2009) Mitsuko Hayashi-Nishino et al.   NATURE CELL BIOLOGY

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

Comparative toxicity of 24 manufactured nanoparticles in human alveolar epithelial and macrophage cell lines

(2009) Sophie Lanone et al.   Particle and Fibre Toxicology

Oxidative Stress Induces Parallel Autophagy and Mitochondria Dysfunction in Human Glioma U251 Cells

(2009) Hongyu Zhang et al.   TOXICOLOGICAL SCIENCES

Induction of chronic inflammation in mice treated with titanium dioxide nanoparticles by intratracheal instillation

(2009) Eun-Jung Park et al.   TOXICOLOGY

Effects of multi-walled carbon nanotubes on a murine allergic airway inflammation model

(2009) Ken-ichiro Inoue et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

PAMAM Nanoparticles Promote Acute Lung Injury by Inducing Autophagic Cell Death through the Akt-TSC2-mTOR Signaling Pathway

(2009) C. Li et al.   Journal of Molecular Cell Biology

Inhaled Multiwalled Carbon Nanotubes Potentiate Airway Fibrosis in Murine Allergic Asthma

(2008) Jessica P. Ryman-Rasmussen et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Clastogenic and aneugenic effects of multi-wall carbon nanotubes in epithelial cells

(2008) Julie Muller et al.   CARCINOGENESIS

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Dynein-dependent Movement of Autophagosomes Mediates Efficient Encounters with Lysosomes

(2008) Shunsuke Kimura et al.   CELL STRUCTURE AND FUNCTION

Cytotoxicity of Titanium Dioxide Nanoparticles in Mouse Fibroblast Cells

(2008) Cheng-Yu Jin et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Evaluating the Toxicity of Airborne Particulate Matter and Nanoparticles by Measuring Oxidative Stress Potential—A Workshop Report and Consensus Statement

(2008) Jon G. Ayres et al.   INHALATION TOXICOLOGY

The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

(2008) Chengyu Liang et al.   NATURE CELL BIOLOGY

Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease

(2008) Zhi-Hua Chen et al.   PLoS One

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Particokinetics and Extrapulmonary Translocation of Intratracheally Instilled Ferric Oxide Nanoparticles in Rats and the Potential Health Risk Assessment

(2008) Mo-Tao Zhu et al.   TOXICOLOGICAL SCIENCES

Increased accumulation of neutrophils and decreased fibrosis in the lung of NADPH oxidase-deficient C57BL/6 mice exposed to carbon nanotubes

(2008) A.A. Shvedova et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Chloroquine-induced nitric oxide increase and cell death is dependent on cellular GSH depletion in A172 human glioblastoma cells

(2008) Byung Chul Park et al.   TOXICOLOGY LETTERS

Studies on the in vitro genotoxicity of baytubes®, agglomerates of engineered multi-walled carbon-nanotubes (MWCNT)

(2008) U. Wirnitzer et al.   TOXICOLOGY LETTERS

The Itinerary of Autophagosomes: From Peripheral Formation to Kiss-and-Run Fusion with Lysosomes

(2008) Luca Jahreiss et al.   TRAFFIC

Sequential Exposure to Carbon Nanotubes and Bacteria Enhances Pulmonary Inflammation and Infectivity

(2007) Anna A. Shvedova et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY