期刊
JOURNAL OF IMMUNOLOGY RESEARCH
卷 2018, 期 -, 页码 -出版社
HINDAWI LTD
DOI: 10.1155/2018/6519465
关键词
-
类别
资金
- National Natural Science Foundation of China [81702439, 81802446]
- Postdoctoral Science Foundation of China [2016M600383]
- Special Funded Projects of China Postdoctoral Science Fund [2017T100337]
The interleukin-(IL-) 17 superfamily, a T cell-derived cytokine, consists of 6 ligands (IL-17A-IL-17F) and 5 receptors (IL-17RA-IL-17RE). IL-17A, a prototype member of this family, is involved in the pathogenesis of allergies, autoimmune diseases, allograft transplantations, and malignancies. By contrast, IL-17B is reported to be closely related to certain diseases, particularly tumors such as breast cancer, gastric cancer, and pancreatic cancer. Recently, the biological function of IL-17E (also called IL-25) in disease, particularly airway diseases, has attracted the attention of researchers. However, studies on IL-25 are scant. In this review, we detail the structural characteristics, expression patterns, responder cells, biological properties, and role of IL-25 in disease pathogenesis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据