标题
New Insights in Cardiac β-Adrenergic Signaling During Heart Failure and Aging
作者
关键词
-
出版物
Frontiers in Pharmacology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-08-10
DOI
10.3389/fphar.2018.00904
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- G protein-coupled receptor kinase 2 (GRK2) as an integrative signalling node in the regulation of cardiovascular function and metabolic homeostasis
- (2018) Federico Mayor et al. CELLULAR SIGNALLING
- Long-Term Caloric Restriction Improves Cardiac Function, Remodeling, Adrenergic Responsiveness, and Sympathetic Innervation in a Model of Postischemic Heart Failure
- (2018) Claudio de Lucia et al. Circulation-Heart Failure
- Echocardiographic Strain Analysis for the Early Detection of Left Ventricular Systolic/Diastolic Dysfunction and Dyssynchrony in a Mouse Model of Physiological Aging
- (2018) Claudio de Lucia et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- β-Arrestin2 Improves Post–Myocardial Infarction Heart Failure via Sarco(endo)plasmic Reticulum Ca 2+ -ATPase–Dependent Positive Inotropy in CardiomyocytesNovelty and Significance
- (2017) Katie A. McCrink et al. HYPERTENSION
- Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine
- (2017) Helen V. Waldschmidt et al. JOURNAL OF MEDICINAL CHEMISTRY
- β 1 -Blockade Prevents Post-Ischemic Myocardial Decompensation Via β 3 AR-Dependent Protective Sphingosine-1 Phosphate Signaling
- (2017) Alessandro Cannavo et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Insulin and β Adrenergic Receptor Signaling: Crosstalk in Heart
- (2017) Qin Fu et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Neuroinflammatory and autonomic mechanisms in diabetes and hypertension
- (2016) Cheng Han et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Cardiac salvage by tweaking with beta-3-adrenergic receptors
- (2016) Jean-Luc Balligand CARDIOVASCULAR RESEARCH
- Prognostic Value of Lymphocyte G Protein-Coupled Receptor Kinase-2 Protein Levels in Patients With Heart FailureNovelty and Significance
- (2016) Giuseppe Rengo et al. CIRCULATION RESEARCH
- GRK2 in Lymphocytes
- (2016) Joshua G. Travers et al. CIRCULATION RESEARCH
- β-adrenergic receptor signalling and its functional consequences in the diseased heart
- (2016) Aref Najafi et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- The first-in-man randomized trial of a beta3 adrenoceptor agonist in chronic heart failure: the BEAT-HF trial
- (2016) Henning Bundgaard et al. EUROPEAN JOURNAL OF HEART FAILURE
- Impact of aging on cardiac sympathetic innervation measured by 123I-mIBG imaging in patients with systolic heart failure
- (2016) Giuseppe Rengo et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Male Lower Urinary Tract Symptoms and Cardiovascular Events: A Systematic Review and Meta-analysis
- (2016) Mauro Gacci et al. EUROPEAN UROLOGY
- Healthy aging and myocardium: A complicated process with various effects in cardiac structure and physiology
- (2016) ES Nakou et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Hypothesis
- (2016) Jonathan M. Powell et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS
- Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors
- (2016) Helen V. Waldschmidt et al. JOURNAL OF MEDICINAL CHEMISTRY
- Sustained βAR Stimulation Mediates Cardiac Insulin Resistance in a PKA-Dependent Manner
- (2016) Supachoke Mangmool et al. MOLECULAR ENDOCRINOLOGY
- Epidemiology and aetiology of heart failure
- (2016) Boback Ziaeian et al. Nature Reviews Cardiology
- Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis
- (2016) Gabriele Giacomo Schiattarella et al. PLoS One
- Spontaneous ventricular tachyarrhythmias in β2-adrenoceptor transgenic mice in relation to cardiac interstitial fibrosis
- (2015) My-Nhan Nguyen et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Insulin induces IRS2-dependent and GRK2-mediated β2AR internalization to attenuate βAR signaling in cardiomyocytes
- (2015) Qin Fu et al. CELLULAR SIGNALLING
- Heart Disease and Stroke Statistics—2016 Update
- (2015) Dariush Mozaffarian et al. CIRCULATION
- Impact of diabetes mellitus on lymphocyte GRK2 protein levels in patients with heart failure
- (2015) Giuseppe Rengo et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Alterations of left ventricular deformation and cardiac sympathetic derangement in patients with systolic heart failure: a 3D speckle tracking echocardiography and cardiac 123I-MIBG study
- (2015) Dario Leosco et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- G-protein-coupled receptor kinases in inflammation and disease
- (2015) N Packiriswamy et al. GENES AND IMMUNITY
- Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy
- (2015) Guanghong Jia et al. Nature Reviews Endocrinology
- The Evolving Impact of G Protein-Coupled Receptor Kinases in Cardiac Health and Disease
- (2015) Priscila Y. Sato et al. PHYSIOLOGICAL REVIEWS
- Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2
- (2015) Rocio Vila-Bedmar et al. Science Signaling
- Paroxetine-mediated GRK2 inhibition reverses cardiac dysfunction and remodeling after myocardial infarction
- (2015) Sarah M. Schumacher et al. Science Translational Medicine
- The Aging Heart: Figure 1.
- (2015) Ying Ann Chiao et al. Cold Spring Harbor Perspectives in Medicine
- Utility of Circulating MicroRNAs as Clinical Biomarkers for Cardiovascular Diseases
- (2015) Altaf A. Kondkar et al. Biomed Research International
- Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2
- (2015) Rocio Vila-Bedmar et al. Science Signaling
- Frailty syndrome and self-care ability in elderly patients with heart failure
- (2015) Izabella Uchmanowicz et al. Clinical Interventions in Aging
- Impact of Diabetes on Epidemiology, Treatment, and Outcomes of Patients With Heart Failure
- (2015) Alessandra Dei Cas et al. JACC-Heart Failure
- Disruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: A novel approach to β-adrenergic receptor blockade
- (2014) Lin Yan et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Downregulation of G protein-coupled receptor kinase 2 levels enhances cardiac insulin sensitivity and switches on cardioprotective gene expression patterns
- (2014) Elisa Lucas et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Increased myocardial dysfunction, dyssynchrony, and epicardial fat across the lifespan in healthy males
- (2014) Edward Crendal et al. BMC Cardiovascular Disorders
- Effect of vildagliptin, a dipeptidyl peptidase 4 inhibitor, on cardiac hypertrophy induced by chronic beta-adrenergic stimulation in rats
- (2014) Toru Miyoshi et al. Cardiovascular Diabetology
- Carvedilol reverses cardiac insufficiency in AKAP5 knockout mice by normalizing the activities of calcineurin and CaMKII
- (2014) X. Li et al. CARDIOVASCULAR RESEARCH
- MicroRNA-133 Modulates the β 1 -Adrenergic Receptor Transduction Cascade
- (2014) Alessandra Castaldi et al. CIRCULATION RESEARCH
- G Protein–Coupled Receptor Kinase 2
- (2014) Meryl C. Woodall et al. CIRCULATION RESEARCH
- Insulin Inhibits Cardiac Contractility by Inducing a Gi-Biased 2-Adrenergic Signaling in Hearts
- (2014) Q. Fu et al. DIABETES
- Demonstration of a Direct Interaction between β2-Adrenergic Receptor and Insulin Receptor by BRET and Bioinformatics
- (2014) Maja Mandić et al. PLoS One
- Adrenal adrenoceptors in heart failure
- (2014) Claudio de Lucia et al. Frontiers in Physiology
- β-adrenergic receptor responsiveness in aging heart and clinical implications
- (2014) Nicola Ferrara et al. Frontiers in Physiology
- Enhanced Expression of β3-Adrenoceptors in Cardiac Myocytes Attenuates Neurohormone-Induced Hypertrophic Remodeling Through Nitric Oxide Synthase
- (2013) Catharina Belge et al. CIRCULATION
- Adrenergic Nervous System in Heart Failure
- (2013) Anastasios Lymperopoulos et al. CIRCULATION RESEARCH
- The role and management of sympathetic overactivity in cardiovascular and renal complications of diabetes
- (2013) P. Iyngkaran et al. DIABETES & METABOLISM
- Incretins: Their physiology and application in the treatment of diabetes mellitus
- (2013) Hale M. Tasyurek et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Negative Impact of β-Arrestin-1 on Post-Myocardial Infarction Heart Failure via Cardiac and Adrenal-Dependent Neurohormonal Mechanisms
- (2013) Ashley Bathgate-Siryk et al. HYPERTENSION
- β-arrestin2 in Infiltrated Macrophages Inhibits Excessive Inflammation after Myocardial Infarction
- (2013) Kenji Watari et al. PLoS One
- Risk of acute myocardial infarction after transurethral resection of prostate in elderly
- (2013) Claudio de Lucia et al. BMC Surgery
- Reduction of lymphocyte G protein-coupled receptor kinase-2 (GRK2) after exercise training predicts survival in patients with heart failure
- (2013) Giuseppe Rengo et al. European Journal of Preventive Cardiology
- Beta3-Adrenoreceptors in Cardiovasular Diseases: New Roles for an “Old” Receptor
- (2013) Jean-Luc Balligand Current Drug Delivery
- Neuro-hormonal effects of physical activity in the elderly
- (2013) Grazia D. Femminella et al. Frontiers in Physiology
- Effects of exercise training on cardiovascular adrenergic system
- (2013) Dario Leosco et al. Frontiers in Physiology
- Targeting cardiac β-adrenergic signaling via GRK2 inhibition for heart failure therapy
- (2013) Alessandro Cannavo et al. Frontiers in Physiology
- Paroxetine Is a Direct Inhibitor of G Protein-Coupled Receptor Kinase 2 and Increases Myocardial Contractility
- (2012) David M. Thal et al. ACS Chemical Biology
- Cardiac Aging: From Molecular Mechanisms to Significance in Human Health and Disease
- (2012) Dao-Fu Dai et al. ANTIOXIDANTS & REDOX SIGNALING
- Blockade of β-adrenoceptors restores the GRK2-mediated adrenal α2-adrenoceptor-catecholamine production axis in heart failure
- (2012) G Rengo et al. BRITISH JOURNAL OF PHARMACOLOGY
- Myocardial β2-adrenoceptor gene delivery promotes coordinated cardiac adaptive remodelling and angiogenesis in heart failure
- (2012) G Rengo et al. BRITISH JOURNAL OF PHARMACOLOGY
- p53-Induced Adipose Tissue Inflammation Is Critically Involved in the Development of Insulin Resistance in Heart Failure
- (2012) Ippei Shimizu et al. Cell Metabolism
- The Intersection Between Aging and Cardiovascular Disease
- (2012) Brian J. North et al. CIRCULATION RESEARCH
- Targeting the β-Adrenergic Receptor System Through G-Protein–Coupled Receptor Kinase 2: A New Paradigm for Therapy and Prognostic Evaluation in Heart Failure
- (2012) Giuseppe Rengo et al. Circulation-Heart Failure
- New strategy for the treatment of type 2 diabetes mellitus with incretin-based therapy
- (2012) Mitsuyoshi Namba et al. Clinical and Experimental Nephrology
- Ageing as a Risk Factor for Disease
- (2012) Teresa Niccoli et al. CURRENT BIOLOGY
- GRK2 Inhibition in Heart Failure: Something Old, Something New
- (2012) Anastasios Lymperopoulos et al. CURRENT PHARMACEUTICAL DESIGN
- AAV6. ARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model
- (2012) P. W. J. Raake et al. EUROPEAN HEART JOURNAL
- The human sympathetic nervous system: its relevance in hypertension and heart failure
- (2012) G. Parati et al. EUROPEAN HEART JOURNAL
- Aging and the Renin-Angiotensin System
- (2012) Sara Conti et al. HYPERTENSION
- Cardioprotective Effect of Beta-3 Adrenergic Receptor Agonism
- (2012) Xiaolin Niu et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Role of soluble adenylyl cyclase in the heart
- (2011) Jonathan Chen et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- G Protein–Coupled Receptor Kinase 2 Activity Impairs Cardiac Glucose Uptake and Promotes Insulin Resistance After Myocardial Ischemia
- (2011) Michele Ciccarelli et al. CIRCULATION
- G Protein–Dependent and G Protein–Independent Signaling Pathways and Their Impact on Cardiac Function
- (2011) Douglas G. Tilley CIRCULATION RESEARCH
- Diabetes and Sepsis: Preclinical Findings and Clinical Relevance
- (2011) P. Schuetz et al. DIABETES CARE
- Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy
- (2011) Andrew J. Boyle et al. EXPERIMENTAL GERONTOLOGY
- Myocardial G Protein Receptor–Coupled Kinase Expression Correlates With Functional Parameters and Clinical Severity in Advanced Heart Failure
- (2011) Jaime Agüero et al. JOURNAL OF CARDIAC FAILURE
- Adrenal Beta-Arrestin 1 Inhibition In Vivo Attenuates Post-Myocardial Infarction Progression to Heart Failure and Adverse Remodeling Via Reduction of Circulating Aldosterone Levels
- (2011) Anastasios Lymperopoulos et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Adenylyl Cyclase 6 Improves Calcium Uptake and Left Ventricular Function in Aged Hearts
- (2011) Tong Tang et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- β-arrestin-mediated receptor trafficking and signal transduction
- (2011) Sudha K. Shenoy et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Aging-Associated Cardiovascular Changes and Their Relationship to Heart Failure
- (2011) James B. Strait et al. Heart Failure Clinics
- Adrenal GRK2 lowering is an underlying mechanism for the beneficial sympathetic effects of exercise training in heart failure
- (2010) Giuseppe Rengo et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- β 3 Adrenergic Stimulation of the Cardiac Na + -K + Pump by Reversal of an Inhibitory Oxidative Modification
- (2010) Henning Bundgaard et al. CIRCULATION
- G Protein-Coupled Receptor Kinase 2 Plays a Relevant Role in Insulin Resistance and Obesity
- (2010) L. Garcia-Guerra et al. DIABETES
- Modulation of β-adrenergic receptor signaling in heart failure and longevity: targeting adenylyl cyclase type 5
- (2010) David Ho et al. HEART FAILURE REVIEWS
- Epidemiology of Incident Heart Failure in a Contemporary Elderly Cohort
- (2009) Andreas Kalogeropoulos et al. ARCHIVES OF INTERNAL MEDICINE
- The G protein coupled receptor kinase 2 plays an essential role in beta-adrenergic receptor-induced insulin resistance
- (2009) Ersilia Cipolletta et al. CARDIOVASCULAR RESEARCH
- Sympathetic Activation in Congestive Heart Failure: Evidence, Consequences and Therapeutic Implications
- (2009) Guido Grassi et al. Current Vascular Pharmacology
- Myocardial Adeno-Associated Virus Serotype 6–βARKct Gene Therapy Improves Cardiac Function and Normalizes the Neurohormonal Axis in Chronic Heart Failure
- (2008) Giuseppe Rengo et al. CIRCULATION
- Beta-Arrestin-Mediated Signaling in the Heart
- (2008) Priyesh A. Patel et al. CIRCULATION JOURNAL
- G Protein–Coupled Receptor Kinase 2 Ablation in Cardiac Myocytes Before or After Myocardial Infarction Prevents Heart Failure
- (2008) Philip W. Raake et al. CIRCULATION RESEARCH
- Gene Therapy in Heart Failure
- (2008) Leif Erik Vinge et al. CIRCULATION RESEARCH
- Activation of Cardiac Adenylyl Cyclase Expression Increases Function of the Failing Ischemic Heart in Mice
- (2008) N. Chin Lai et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More