Pharmacological c-Jun NH2-Terminal Kinase (JNK) Pathway Inhibition Reduces Severity of Spinal Muscular Atrophy Disease in Mice
出版年份 2018 全文链接
标题
Pharmacological c-Jun NH2-Terminal Kinase (JNK) Pathway Inhibition Reduces Severity of Spinal Muscular Atrophy Disease in Mice
作者
关键词
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出版物
Frontiers in Molecular Neuroscience
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-09-04
DOI
10.3389/fnmol.2018.00308
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Increase of hyperpolarization-activated cyclic nucleotide-gated current in the aberrant excitability of spinal muscular atrophy
- (2018) Hsing-Jung Lai et al. ANNALS OF NEUROLOGY
- Time Is Motor Neuron: Therapeutic Window and Its Correlation with Pathogenetic Mechanisms in Spinal Muscular Atrophy
- (2018) Alessandra Govoni et al. MOLECULAR NEUROBIOLOGY
- Autophagy inhibition: a new therapeutic target in spinal muscular atrophy
- (2018) Antonio Piras et al. Neural Regeneration Research
- Increasing Agrin Function Antagonizes Muscle Atrophy and Motor Impairment in Spinal Muscular Atrophy
- (2018) Marina Boido et al. Frontiers in Cellular Neuroscience
- The clinical landscape for SMA in a new therapeutic era
- (2017) K Talbot et al. GENE THERAPY
- Regulation of Survival Motor Neuron Protein by the Nuclear Factor-Kappa B Pathway in Mouse Spinal Cord Motoneurons
- (2017) Saravanan Arumugam et al. MOLECULAR NEUROBIOLOGY
- Making sense of antisense oligonucleotides: A narrative review
- (2017) Neelam Goyal et al. MUSCLE & NERVE
- ERK and ROCK functionally interact in a signaling network that is compensationally upregulated in Spinal Muscular Atrophy
- (2017) Niko Hensel et al. NEUROBIOLOGY OF DISEASE
- Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy
- (2017) Jerry R. Mendell et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inhibition of autophagy delays motoneuron degeneration and extends lifespan in a mouse model of spinal muscular atrophy
- (2017) Antonio Piras et al. Cell Death & Disease
- Motor Neuron Gene Therapy: Lessons from Spinal Muscular Atrophy for Amyotrophic Lateral Sclerosis
- (2017) Andrew P. Tosolini et al. Frontiers in Molecular Neuroscience
- New insights into SMA pathogenesis: immune dysfunction and neuroinflammation
- (2017) Marc-Olivier Deguise et al. Annals of Clinical and Translational Neurology
- Vascular Defects and Spinal Cord Hypoxia in Spinal Muscular Atrophy
- (2016) Eilidh Somers et al. ANNALS OF NEUROLOGY
- Nusinersen potentially effective in SMA
- (2016) Louise Adams Nature Reviews Neurology
- Neuromuscular Junctions as Key Contributors and Therapeutic Targets in Spinal Muscular Atrophy
- (2016) Marina Boido et al. Frontiers in Neuroanatomy
- Is spinal muscular atrophy a disease of the motor neurons only: pathogenesis and therapeutic implications?
- (2015) Chiara Simone et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Genetic inhibition of JNK3 ameliorates spinal muscular atrophy
- (2015) Naresh K. Genabai et al. HUMAN MOLECULAR GENETICS
- Astrocytes influence the severity of spinal muscular atrophy
- (2015) Hansjörg Rindt et al. HUMAN MOLECULAR GENETICS
- IGF-1R Reduction Triggers Neuroprotective Signaling Pathways in Spinal Muscular Atrophy Mice
- (2015) O. Biondi et al. JOURNAL OF NEUROSCIENCE
- Expression of Muscle-Specific MiRNA 206 in the Progression of Disease in a Murine SMA Model
- (2015) Valeria Valsecchi et al. PLoS One
- Mechanisms controlling neuromuscular junction stability
- (2014) Evelyne Bloch-Gallego CELLULAR AND MOLECULAR LIFE SCIENCES
- Induction of phosphorylated c-Jun in neonatal spinal motoneurons after axonal injury is coincident with both motoneuron death and regeneration
- (2014) Qiuju Yuan et al. JOURNAL OF ANATOMY
- Multiplexed immunohistochemistry, imaging, and quantitation: A review, with an assessment of Tyramide signal amplification, multispectral imaging and multiplex analysis
- (2014) Edward C. Stack et al. METHODS
- Nuclear and cytosolic JNK signalling in neurons
- (2014) Eleanor T. Coffey NATURE REVIEWS NEUROSCIENCE
- c-Jun N-terminal kinase has a key role in Alzheimer disease synaptic dysfunction in vivo
- (2014) A Sclip et al. Cell Death & Disease
- Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production
- (2013) Jered V. McGivern et al. GLIA
- Spinal muscular atrophy: a motor neuron disorder or a multi-organ disease?
- (2013) Monir Shababi et al. JOURNAL OF ANATOMY
- Shift from Extracellular Signal-Regulated Kinase to AKT/cAMP Response Element-Binding Protein Pathway Increases Survival-Motor-Neuron Expression in Spinal-Muscular-Atrophy-Like Mice and Patient Cells
- (2013) J. Branchu et al. JOURNAL OF NEUROSCIENCE
- ROLE of exercise in maintaining the integrity of the neuromuscular junction
- (2013) Hiroshi Nishimune et al. MUSCLE & NERVE
- Selective Vulnerability of Spinal and Cortical Motor Neuron Subpopulations in delta7 SMA Mice
- (2013) Paolo d’Errico et al. PLoS One
- Soluble Aβ oligomer-induced synaptopathy: c-Jun N-terminal kinase's role
- (2013) Alessandra Sclip et al. Journal of Molecular Cell Biology
- Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy
- (2012) Melissa Bowerman et al. BMC Medicine
- Disruption of Axonal Transport in Motor Neuron Diseases
- (2012) Kensuke Ikenaka et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- c-Jun N-terminal Kinase 1 (JNK1) Is Required for Coordination of Netrin Signaling in Axon Guidance
- (2012) Chao Qu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of JNK Isoforms in the Development of Neuropathic Pain following Sciatic Nerve Transection in the Mouse
- (2012) Giusi Manassero et al. Molecular Pain
- Dysfunction of the neuromuscular junction in spinal muscular atrophy types 2 and 3
- (2012) R. I. Wadman et al. NEUROLOGY
- Synaptic defects in spinal muscular atrophy animal models
- (2011) Laura Torres-Benito et al. Developmental Neurobiology
- JNK regulates FoxO-dependent autophagy in neurons
- (2011) P. Xu et al. GENES & DEVELOPMENT
- Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy
- (2011) K. K. Y. Ling et al. HUMAN MOLECULAR GENETICS
- c-Jun N-terminal Kinase Regulates Soluble Aβ Oligomers and Cognitive Impairment in AD Mouse Model
- (2011) Alessandra Sclip et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway
- (2011) Faraz Farooq et al. JOURNAL OF CLINICAL INVESTIGATION
- The JNK inhibitor D-JNKI-1 blocks apoptotic JNK signaling in brain mitochondria
- (2011) Yi Zhao et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Spinal muscular atrophy
- (2011) Adele D'Amico et al. Orphanet Journal of Rare Diseases
- c-Jun N-terminal kinase signaling pathway in excitotoxic cell death following kainic acid-induced status epilepticus
- (2010) Giada Spigolon et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Stem cell-derived neurotrophic support for the neuromuscular junction in spinal muscular atrophy
- (2010) Tanya J Wyatt et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Arrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice
- (2010) Christopher R. Heier et al. HUMAN MOLECULAR GENETICS
- Early heart failure in the SMNΔ7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery
- (2010) Adam K. Bevan et al. HUMAN MOLECULAR GENETICS
- Rho-kinase inactivation prolongs survival of an intermediate SMA mouse model
- (2010) Mélissa Bowerman et al. HUMAN MOLECULAR GENETICS
- Spinal muscular atrophy: mechanisms and therapeutic strategies
- (2010) C. L. Lorson et al. HUMAN MOLECULAR GENETICS
- In Vivo NMDA Receptor Activation Accelerates Motor Unit Maturation, Protects Spinal Motor Neurons, and Enhances SMN2 Gene Expression in Severe Spinal Muscular Atrophy Mice
- (2010) O. Biondi et al. JOURNAL OF NEUROSCIENCE
- The JNK MAP kinase pathway contributes to the development of endotoxin-induced diaphragm caspase activation
- (2009) Gerald S. Supinski et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Hyperphosphorylation and Accumulation of Neurofilament Proteins in Transgenic Mice with Alzheimer Presenilin 1 Mutation
- (2009) Xifei Yang et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Selective inhibition of JNK with a peptide inhibitor attenuates pain hypersensitivity and tumor growth in a mouse skin cancer pain model
- (2009) Yong-Jing Gao et al. EXPERIMENTAL NEUROLOGY
- Impaired Synaptic Vesicle Release and Immaturity of Neuromuscular Junctions in Spinal Muscular Atrophy Mice
- (2009) L. Kong et al. JOURNAL OF NEUROSCIENCE
- Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?
- (2009) Arthur H. M. Burghes et al. NATURE REVIEWS NEUROSCIENCE
- Identification of a battery of tests for drug candidate evaluation in the SMNΔ7 neonate model of spinal muscular atrophy
- (2008) Bassem F. El-Khodor et al. EXPERIMENTAL NEUROLOGY
- Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy
- (2008) Shingo Kariya et al. HUMAN MOLECULAR GENETICS
- Plastin 3 Is a Protective Modifier of Autosomal Recessive Spinal Muscular Atrophy
- (2008) G. E. Oprea et al. SCIENCE
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