Structures of inactive CRP species reveal the atomic details of the allosteric transition that discriminates cyclic nucleotide second messengers

A cyclic GMP-dependent signalling pathway regulates bacterial phytopathogenesis

(2013) Shi-Qi An et al.   EMBO JOURNAL

Bacterial second messengers, cGMP and c-di-GMP, in a quest for regulatory dominance

(2013) Mark Gomelsky et al.   EMBO JOURNAL

A Secondary Structural Transition in the C-helix Promotes Gating of Cyclic Nucleotide-regulated Ion Channels

(2013) Michael C. Puljung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordination of bacterial proteome with metabolism by cyclic AMP signalling

(2013) Conghui You et al.   NATURE

Allosteric inhibition through suppression of transient conformational states

(2013) Shiou-Ru Tzeng et al.   Nature Chemical Biology

Dynamic binding

(2012) Andrew J. Baldwin et al.   NATURE

Protein activity regulation by conformational entropy

(2012) Shiou-Ru Tzeng et al.   NATURE

X-ray crystal structure of TTHB099, a CRP/FNR superfamily transcriptional regulator from thermus thermophilus HB8, reveals a DNA-binding protein with no required allosteric effector molecule

(2012) Yoshihiro Agari et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structure and Allostery of the PKA RII  Tetrameric Holoenzyme

(2012) P. Zhang et al.   SCIENCE

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Cyclic GMP controls Rhodospirillum centenum cyst development

(2011) Jeremiah N. Marden et al.   MOLECULAR MICROBIOLOGY

Co-Crystal Structures of PKG Iβ (92–227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding

(2011) Jeong Joo Kim et al.   PLoS One

Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel

(2011) S. Schunke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mapping Conformational Transitions in Cyclic AMP Receptor Protein: Crystal Structure and Normal-Mode Analysis of Mycobacterium tuberculosis apo-cAMP Receptor Protein

(2010) Pramod Kumar et al.   BIOPHYSICAL JOURNAL

cAMP, c-di-GMP, c-di-AMP and now cGMP: bacteria use them all!

(2010) Mark Gomelsky   MOLECULAR MICROBIOLOGY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural overview on the allosteric activation of cyclic AMP receptor protein

(2009) Hyung-Sik Won et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Profound Asymmetry in the Structure of the cAMP-free cAMP Receptor Protein (CRP) fromMycobacterium tuberculosis

(2009) D. Travis Gallagher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamically Driven Ligand Selectivity in Cyclic Nucleotide Binding Domains

(2009) Rahul Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insights into the Mechanism of the Allosteric Transitions ofMycobacterium tuberculosiscAMP Receptor Protein

(2009) Manchi C. M. Reddy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

cGMP production in bacteria

(2009) Jürgen U. Linder   MOLECULAR AND CELLULAR BIOCHEMISTRY

Dynamic activation of an allosteric regulatory protein

(2009) Shiou-Ru Tzeng et al.   NATURE

Structure of apo-CAP reveals that large conformational changes are necessary for DNA binding

(2009) H. Sharma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for cAMP-mediated allosteric control of the catabolite activator protein

(2009) N. Popovych et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Syn,anti, and finally both conformations of cyclic AMP are involved in the CRP-dependent transcription initiation mechanism inE. coli lac operon

(2008) Yusuf Tutar   CELL BIOCHEMISTRY AND FUNCTION

Structural and Energetic Analysis of Activation by a Cyclic Nucleotide Binding Domain

(2008) Stephen L. Altieri et al.   JOURNAL OF MOLECULAR BIOLOGY

Global gene expression mediated by Thermus thermophilus SdrP, a CRP/FNR family transcriptional regulator

(2008) Yoshihiro Agari et al.   MOLECULAR MICROBIOLOGY