Allosteric inhibition through suppression of transient conformational states

Protein activity regulation by conformational entropy

(2012) Shiou-Ru Tzeng et al.   NATURE

Evidence for dynamics in proteins as a mechanism for ligand dissociation

(2012) Mary J Carroll et al.   Nature Chemical Biology

Structure of an Intermediate State in Protein Folding and Aggregation

(2012) P. Neudecker et al.   SCIENCE

Excited-State Control of Protein Activity

(2011) Michele Vendruscolo   JOURNAL OF MOLECULAR BIOLOGY

cAMP-Dependent Protein Kinase A Selects the Excited State of the Membrane Substrate Phospholamban

(2011) Larry R. Masterson et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Instability Tuning as a Regulatory Mechanism in Protein-Protein Interactions

(2011) Li Chen et al.   MOLECULAR CELL

Solution structure of a minor and transiently formed state of a T4 lysozyme mutant

(2011) Guillaume Bouvignies et al.   NATURE

Allostery in pharmacology: Thermodynamics, evolution and design

(2011) Gábor Maksay   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Protein dynamics and allostery: an NMR view

(2010) Shiou-Ru Tzeng et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Nanometer Propagation of Millisecond Motions in V-Type Allostery

(2010) James M. Lipchock et al.   STRUCTURE

TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts

(2009) Yang Shen et al.   JOURNAL OF BIOMOLECULAR NMR

Dynamic activation of an allosteric regulatory protein

(2009) Shiou-Ru Tzeng et al.   NATURE

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

NMR spectroscopy brings invisible protein states into focus

(2009) Andrew J Baldwin et al.   Nature Chemical Biology

Structural basis for cAMP-mediated allosteric control of the catabolite activator protein

(2009) N. Popovych et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trapping Moving Targets with Small Molecules

(2009) G. M. Lee et al.   SCIENCE

In search of negative allosteric modulators of biological targets

(2008) Duncan R. Groebe   DRUG DISCOVERY TODAY

Two-State Allosteric Modeling Suggests Protein Equilibrium as an Integral Component for Cyclic AMP (cAMP) Specificity in the cAMP Receptor Protein of Escherichia coli

(2008) H. Youn et al.   JOURNAL OF BACTERIOLOGY