Multiple variants aggregate in the neuregulin signaling pathway in a subset of schizophrenia patients

BACE1 Dependent Neuregulin Processing: Review

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Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

(2012) S Hong Lee et al.   NATURE GENETICS

Puzzling over schizophrenia: Schizophrenia as a pathway disease

(2012) Patrick F Sullivan   NATURE MEDICINE

Genetic architectures of psychiatric disorders: the emerging picture and its implications

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De novo mutations in human genetic disease

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SIFT web server: predicting effects of amino acid substitutions on proteins

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Differential Neuregulin 1 Cleavage in the Prefrontal Cortex and Hippocampus in Schizophrenia and Bipolar Disorder: Preliminary Findings

(2012) Ketan Marballi et al.   PLoS One

Proteomics Tackling Schizophrenia as a Pathway Disorder

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De Novo Mutation in Schizophrenia

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Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia

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Exome sequencing supports a de novo mutational paradigm for schizophrenia

(2011) Bin Xu et al.   NATURE GENETICS

Increased exonic de novo mutation rate in individuals with schizophrenia

(2011) Simon L Girard et al.   NATURE GENETICS

Genome-wide association study identifies five new schizophrenia loci

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Interaction between FEZ1 and DISC1 in Regulation of Neuronal Development and Risk for Schizophrenia

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High Frequencies of De Novo CNVs in Bipolar Disorder and Schizophrenia

(2011) Dheeraj Malhotra et al.   NEURON

Reduced Fertility and Fecundity among Patients with Bipolar I Disorder and Schizophrenia in Egypt

(2011) Hader Mansour et al.   Psychiatry Investigation

Effective detection of rare variants in pooled DNA samples using Cross-pool tailcurve analysis

(2011) Tejasvi S Niranjan et al.   GENOME BIOLOGY

A systematic review and meta-analysis of the fertility of patients with schizophrenia and their unaffected relatives

(2010) H. Bundy et al.   ACTA PSYCHIATRICA SCANDINAVICA

Neuregulin 3 (NRG3) as a susceptibility gene in a schizophrenia subtype with florid delusions and relatively spared cognition

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The environment and schizophrenia

(2010) Jim van Os et al.   NATURE

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain

(2010) W.-T. Kao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Replication of an association of a common variant in the Reelin gene (RELN) with schizophrenia in Ashkenazi Jewish women

(2010) Yaping Liu et al.   PSYCHIATRIC GENETICS

Fine Mapping on Chromosome 10q22-q23 Implicates Neuregulin 3 in Schizophrenia

(2009) Pei-Lung Chen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Support for NRG1 as a Susceptibility Factor for Schizophrenia in a Northern Swedish Isolated Population

(2009) Maaike Alaerts et al.   ARCHIVES OF GENERAL PSYCHIATRY

Familiality of Novel Factorial Dimensions of Schizophrenia

(2009) John A. McGrath et al.   ARCHIVES OF GENERAL PSYCHIATRY

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

A 5′ promoter region SNP in NRG1 is associated with schizophrenia risk and type III isoform expression

(2009) K K Nicodemus et al.   MOLECULAR PSYCHIATRY

Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms

(2009) P A Holmans et al.   MOLECULAR PSYCHIATRY

Support for Neuregulin 1 as a Susceptibility Gene for Bipolar Disorder and Schizophrenia

(2008) Lyudmila Georgieva et al.   BIOLOGICAL PSYCHIATRY

Strong association of de novo copy number mutations with sporadic schizophrenia

(2008) Bin Xu et al.   NATURE GENETICS

Neuregulin 1 in neural development, synaptic plasticity and schizophrenia

(2008) Lin Mei et al.   NATURE REVIEWS NEUROSCIENCE

Deficiency of Aph1B/C- -secretase disturbs Nrg1 cleavage and sensorimotor gating that can be reversed with antipsychotic treatment

(2008) T. Dejaegere et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice

(2008) A. V. Savonenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elevated neuregulin-1 and ErbB4 protein in the prefrontal cortex of schizophrenic patients

(2008) Victor Z. Chong et al.   SCHIZOPHRENIA RESEARCH

Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

(2008) T. Walsh et al.   SCIENCE

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE