Nurturing the genome

The R527H mutation in LMNA gene causes an increased sensitivity to ionizing radiation

(2011) Alessandra di Masi et al.   CELL CYCLE

Loss of A-type lamins and genomic instability

(2011) Ignacio Gonzalez-Suarez et al.   CELL CYCLE

Identification of a perinuclear positioning element in human subtelomeres that requires A-type lamins and CTCF

(2009) Alexandre Ottaviani et al.   EMBO JOURNAL

Novel roles for A-type lamins in telomere biology and the DNA damage response pathway

(2009) Ignacio Gonzalez-Suarez et al.   EMBO JOURNAL

Telomere length in Hutchinson-Gilford Progeria Syndrome

(2009) Michelle L. Decker et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Flap Endonuclease 1 Contributes to Telomere Stability

(2008) Abhishek Saharia et al.   CURRENT BIOLOGY

The nuclear lamina promotes telomere aggregation and centromere peripheral localization during senescence of human mesenchymal stem cells

(2008) V. Raz et al.   JOURNAL OF CELL SCIENCE

Suppression of Proliferative Defects Associated with Processing-defective Lamin A Mutants by hTERT or Inactivation of p53

(2008) Brian A. Kudlow et al.   MOLECULAR BIOLOGY OF THE CELL

53BP1 facilitates long-range DNA end-joining during V(D)J recombination

(2008) Simone Difilippantonio et al.   NATURE

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

(2008) Nadya Dimitrova et al.   NATURE

Tethering by lamin A stabilizes and targets the ING1 tumour suppressor

(2008) Xijing Han et al.   NATURE CELL BIOLOGY

Lamin A/C Is a Risk Biomarker in Colorectal Cancer

(2008) Naomi D. Willis et al.   PLoS One

The Histone H3K79 Methyltransferase Dot1L Is Essential for Mammalian Development and Heterochromatin Structure

(2008) Brendan Jones et al.   PLoS Genetics

Accelerated telomere shortening and replicative senescence in human fibroblasts overexpressing mutant and wild-type lamin A

(2007) Shurong Huang et al.   EXPERIMENTAL CELL RESEARCH

Involvement of xeroderma pigmentosum group A (XPA) in progeria arising from defective maturation of prelamin A

(2007) Yiyong Liu et al.   FASEB JOURNAL