Review
Neurosciences
Jonathan G. Hanley
Summary: AMPA receptors play a critical role in synaptic transmission and brain function, with their expression at synapses determining functional connectivity of neuronal circuits and underpinning learning and memory. Dysregulation of excitatory synaptic transmission and plasticity processes is involved in various neurological disorders. MiRNAs play a role in regulating AMPAR subunit expression and synaptic plasticity, potentially contributing to both physiological and pathological changes in the brain.
Review
Cell Biology
Sabrina Carrella, Sandro Banfi, Marianthi Karali
Summary: Photoreceptors are specialized neuroepithelial cells responsible for sensory transduction of light stimuli in the retina. Due to their function, photoreceptors are exposed to continuous cellular stress, requiring tightly regulated molecular mechanisms for maintaining their function, with non-coding RNAs playing a central role.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Review
Cell Biology
Zhi Xiong Chong, Swee Keong Yeap, Wan Yong Ho
Summary: This review discusses the roles of miRNAs in regulating autophagy in breast cancer, and how this can influence disease progression and treatment response. MiRNAs can modulate autophagy activity, affecting proliferation and cell death in human breast cancer cells. Utilizing miRNAs as biomarkers and therapeutic targets may be a promising direction for future breast cancer treatment.
JOURNAL OF BIOMEDICAL SCIENCE
(2021)
Article
Fisheries
Wei Zhou, Yadong Xie, Yu Li, Mingxu Xie, Zhen Zhang, Yalin Yang, Zhigang Zhou, Ming Duan, Chao Ran
Summary: miRNAs are a class of highly conserved, small non-coding RNA molecules with a length of 18-25 nucleotides that negatively regulate target genes through complementary pairing with mRNA. Recent research has shown that miRNAs play important roles in regulating fish nutrition and immunity, including influencing fatty acid synthesis and involvement in antibacterial and antiviral immune responses.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Review
Oncology
Amy L. Baker, Liqin Du
Summary: The SAPCD2 gene encodes a protein with functions beyond regulating cell cycle progression, including modulation of cell polarization and determination of cell fate in embryonic development. Its oncogenic mechanisms have been studied and show potential as a diagnostic marker and therapeutic target for cancers. However, further research is needed to fully understand its oncogenic mechanisms and its role in other pathological processes.
Review
Immunology
Muhammad Nadeem Abbas, Saima Kausar, Bibi Asma, Wenhao Ran, Jingui Li, Zini Lin, Tiejun Li, Hongjuan Cui
Summary: The interaction between bacteria and insects has widespread implications due to their global distribution. It can directly impact human health as insects serve as disease vectors, and also have economic consequences. Moreover, it is linked to high mortality rates in economically important insects, resulting in significant economic losses.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Oncology
Qi Zheng, Wei Hou
Summary: MicroRNAs (miRs) are small non-coding RNA molecules that play key roles in regulating gene expression and cellular functions, particularly in angiogenesis related to tumor development and progression. Investigating the roles of miRs in angiogenesis may lead to novel strategies for treating tumors, and their potential as biomarkers for diagnosing and monitoring therapy response is also being explored.
MOLECULAR MEDICINE REPORTS
(2021)
Article
Multidisciplinary Sciences
Xin Yang, Xuegao Wei, Jing Yang, Tianhua Du, Cheng Yin, Buli Fu, Mingjiao Huang, Jinjin Liang, Peipan Gong, Shaonan Liu, Wen Xie, Zhaojiang Guo, Shaoli Wang, Qingjun Wu, Ralf Nauen, Xuguo Zhou, Chris Bass, Youjun Zhang
Summary: The study reveals the significant role of m(6)A modification in regulating a gene associated with insecticide resistance in the global whitefly pest Bemisia tabaci. This finding sheds light on the biological function of m(6)A in insects and provides a new avenue for investigating the development of insecticide resistance.
Review
Biochemistry & Molecular Biology
Junyan Qu, Zhenghong Lin
Summary: This article summarized the latest advances in the regulation of autophagy by the crosstalk between miRNA and E3 ubiquitin ligases or deubiquitinases, highlighting the key roles played by their interaction in various diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Nutrition & Dietetics
Abdul Fatah A. Samad, Mohd Farizal Kamaroddin, Muhammad Sajad
Summary: miRNAs are well-known for their regulatory roles in genetic systems of mammals and plants, acting post-transcriptionally to regulate gene expression. Recently, plant-derived miRNAs have been found to have the ability to regulate gene expression in mammals, sparking discussions among researchers. The transfer of plant miRNAs through diet and their ability to survive in the digestive tract, enter the circulatory system, and regulate endogenous mRNAs have opened up new possibilities for research and potential applications in dietary therapy.
ADVANCES IN NUTRITION
(2021)
Review
Biochemistry & Molecular Biology
Raquel Grinan, Joan Carles Escola-Gil, Josep Julve, Sonia Benitez, Noemi Rotllan
Summary: Increased serum levels of homocysteine (Hcy) are associated with cardiovascular disease, particularly atherosclerosis. The role of Hcy in this condition is not well understood, but epigenetic modifications and miRNAs may play important roles. MiRNAs have been shown to regulate cell proliferation, cholesterol accumulation, inflammation, and plaque formation in atherosclerosis. They may also serve as potential biomarkers for HHcy-induced atherosclerosis. MiRNA-based therapies show promise for managing Hcy-induced atherosclerosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Esperanza Jimenez, Dolores Piniella, Cecilio Gimenez, Francisco Zafra
Summary: The glycine transporter GLYT1 is regulated by microRNAs, with miR-96 and miR-137 specifically downregulating its expression through targeting the 3'UTR. It suggests that miR-96 may play a significant role in regulating GLYT1 expression under physiological conditions.
NEUROCHEMICAL RESEARCH
(2022)
Article
Plant Sciences
Shivani Kansal, Vaishali Panwar, Roseeta Devi Mutum, Saurabh Raghuvanshi
Summary: This study demonstrates the active involvement of [Ca2+](cyt) in regulating the expression of miRNA genes in rice, especially under stress conditions. Calmodulins and Calmodulin-binding Transcription Activators are identified as crucial components of the signal transduction schema that regulates miRNA expression.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Cell Biology
Edwin C. Fluck, Aysenur Torun Yazici, Tibor Rohacs, Vera Y. Moiseenkova-Bell
Summary: Transient receptor potential vanilloid 5 (TRPV5) is a calcium-selective ion channel that plays a crucial role in maintaining calcium homeostasis in the kidney. This study investigates the regulation of TRPV5 by phosphatidylinositol 4,5-bisphosphate (PI(4,5)P-2) and calmodulin (CaM), as well as the effects of parathyroid hormone (PTH), metabolic acidosis, and protein kinase A (PKA) on TRPV5 activity. The findings reveal that low pH inhibits TRPV5 by preventing PI(4,5)P-2 activation, and PKA controls TRPV5 activity by preventing CaM binding and channel inactivation.
Article
Biodiversity Conservation
Yihao Ge, Zhenyuan Liu, Jorge Garcia-Giron, Xiao Chen, Yunzhi Yan, Zhengfei Li, Zhicai Xie
Summary: This study contributes to a better understanding of multiple diversity patterns in aquatic insect communities by generating new empirical evidence of human-induced degradation of subtropical stream ecosystems in China.
ECOLOGICAL INDICATORS
(2022)
Article
Multidisciplinary Sciences
Zhiwei Chen, Junko Nohata, Huizhen Guo, Shenglong Li, Jianqiu Liu, Youbing Guo, Kimiko Yamamoto, Keiko Kadono-Okuda, Chun Liu, Kallare P. Arunkumar, Javaregowda Nagaraju, Yan Zhang, Shiping Liu, Vassiliki Labropoulou, Luc Swevers, Panagiota Tsitoura, Kostas Iatrou, Karumathil P. Gopinathan, Marian R. Goldsmith, Qingyou Xia, Kazuei Mita
SCIENTIFIC REPORTS
(2015)
Article
Multidisciplinary Sciences
Zhiwei Chen, Junko Nohata, Huizhen Guo, Shenglong Li, Jianqiu Liu, Youbing Guo, Kimiko Yamamoto, Keiko Kadono-Okuda, Chun Liu, Kallare P. Arunkumar, Javaregowda Nagaraju, Yan Zhang, Shiping Liu, Vassiliki Labropoulou, Luc Swevers, Panagiota Tsitoura, Kostas Iatrou, Karumathil P. Gopinathan, Marian R. Goldsmith, Qingyou Xia, Kazuei Mita
Article
Biochemistry & Molecular Biology
Liang Jiang, Tingcai Cheng, Yinghui Dang, Zhengwen Peng, Ping Zhao, Shiping Liu, Shengkai Jin, Ping Lin, Qiang Sun, Qingyou Xia
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2013)
Correction
Biotechnology & Applied Microbiology
Shiping Liu, Liang Zhang, Qibin Li, Ping Zhao, Jun Duan, Daojun Cheng, Zhonghuai Xiang, Qingyou Xia
Article
Genetics & Heredity
Yan Zhang, Zhaoming Dong, Shiping Liu, Qiang Yang, Ping Zhao, Qingyou Xia
FUNCTIONAL & INTEGRATIVE GENOMICS
(2012)
Article
Biochemistry & Molecular Biology
Youshan Li, Ping Zhao, Shiping Liu, Zhaoming Dong, Jianping Chen, Zhonghuai Xiang, Qingyou Xia
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2012)
Article
Multidisciplinary Sciences
Xiao-wu Zhong, Yong Zou, Shi-ping Liu, Qi-ying Yi, Cui-mei Hu, Chen Wang, Qing-you Xia, Ping Zhao
Article
Multidisciplinary Sciences
Chun Liu, Kimiko Yamamoto, Ting-Cai Cheng, Keiko Kadono-Okuda, Junko Narukawa, Shi-Ping Liu, Yu Han, Ryo Futahashi, Kurako Kidokoro, Hiroaki Noda, Isao Kobayashi, Toshiki Tamura, Akio Ohnuma, Yutaka Banno, Fang-Ying Dai, Zhong-Huai Xiang, Marian R. Goldsmith, Kazuei Mita, Qing-You Xia
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2010)
Article
Multidisciplinary Sciences
Shiping Liu, Keira J. Lucas, Sourav Roy, Jisu Ha, Alexander S. Raikhel
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2014)
Article
Parasitology
Xuemei Li, Jinyu Yang, Qian Pu, Xinyue Peng, Lili Xu, Shiping Liu
PARASITES & VECTORS
(2019)
Article
Biochemistry & Molecular Biology
Wei Wang, Xinran Wang, Chengyi Luo, Qian Pu, Quan Yin, Lili Xu, Xinyue Peng, Sanyuan Ma, Qingyou Xia, Shiping Liu
Article
Developmental Biology
Enxiang Chen, Zhiwei Chen, Shenglong Li, Dongxu Xing, Huizhen Guo, Jianqiu Liu, Xiaocun Ji, Ying Lin, Shiping Liu, Qingyou Xia
Article
Biochemistry & Molecular Biology
Xiaoli Jin, Xiaoyan Wu, Lanting Zhou, Ting He, Quan Yin, Shiping Liu
Article
Parasitology
Yangrui Luo, Dun Liu, Yuanmei Wang, Fan Zhang, Yankun Xu, Qian Pu, Lu Zhao, Tianqi Wei, Ting Fan, Yuqi Lou, Shiping Liu
Summary: This study investigates the differential accumulation of proteins and metabolites in miR-1174-depleted Ae. aegypti mosquitoes using proteomic and metabolomic techniques. It identifies the upregulated gene PNP as playing a key role in gut physiological activities.
PARASITES & VECTORS
(2023)
Article
Biology
Erika Machtinger, Karen C. Poh, Risa Pesapane, Danielle M. Tufts
Summary: Vector-borne diseases, transmitted by insects, are a significant threat to global human and animal health. Their emergence is influenced by factors such as environmental changes, host characteristics, and human behavior. The One Health approach is necessary to comprehensively investigate tick-borne diseases and understand the complex interactions between environmental, animal, and human health.
CURRENT OPINION IN INSECT SCIENCE
(2024)
Article
Biology
Pablo Urbaneja-Bernat, Alejandro Tena, Joel Gonzalez-Cabrera, Cesar Rodriguez-Saona
Summary: This article reviews the potential role of plant guttation as a food source for natural enemies, discussing its nutritional value, effects on insect communities, and potential use in conservation biological control.
CURRENT OPINION IN INSECT SCIENCE
(2024)
Article
Biology
Alina A. Mikhailova, Sarah Rinke, Mark C. Harrison
Summary: The genomes of eusocial insects allow the production and regulation of highly distinct phenotypes, largely independent of genotype. Eusociality has evolved convergently in at least three insect orders, but eusocial phenotypes show remarkable similarity. Increased regulatory complexity and the adaptive evolution of chemical communication are common genomic signatures of eusociality. Colony life itself can shape genomes of divergent taxa in a similar manner.
CURRENT OPINION IN INSECT SCIENCE
(2024)
Article
Biology
Dequn Teng, Wei Zhang
Summary: Butterfly wings, with their rich phenotypic diversity and complex biological functions, serve as a crucial system for studying the genetic basis and evolution of phenotypic diversification. Recent studies have revealed the complex functions and genetic and environmental factors involved in determining wing patterns. These factors lead to inter-specific divergence, genetic polymorphism, and phenotypic plasticity, often controlled by key genes. Gene co-option has also been identified as an important mechanism for functional complexity and evolutionary novelty. However, further research is needed for a systematic and comprehensive understanding.
CURRENT OPINION IN INSECT SCIENCE
(2024)
