Immune response to influenza vaccination in the elderly is altered by chronic medication use

Update: Influenza Activity — United States, October 1, 2017–February 3, 2018

(2018) Alicia P. Budd et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Original antigenic sin: A comprehensive review

(2017) Anup Vatti et al.   JOURNAL OF AUTOIMMUNITY

Concentration-dependent metabolic effects of metformin in healthy and Fanconi anemia lymphoblast cells

(2017) Silvia Ravera et al.   JOURNAL OF CELLULAR PHYSIOLOGY

γδ T Cells Are Required for the Induction of Sterile Immunity during Irradiated Sporozoite Vaccinations

(2017) Irfan Zaidi et al.   JOURNAL OF IMMUNOLOGY

The effect of timing of influenza vaccination and sample collection on antibody titers and responses in the aged

(2017) Raj K. Kurupati et al.   VACCINE

Metformin improves in vivo and in vitro B cell function in individuals with obesity and Type-2 Diabetes

(2017) Alain Diaz et al.   VACCINE

Germinal center B cell development has distinctly regulated stages completed by disengagement from T cell help

(2017) Ting-ting Zhang et al.   eLife

Sirtuin 1 (Sirt1) Overexpression in BaF3 Cells Contributes to Cell Proliferation Promotion, Apoptosis Resistance and Pro-Inflammatory Cytokine Production

(2017) Qian Wang et al.   MEDICAL SCIENCE MONITOR

Nonsteroidal Anti-Inflammatory Drug and Aspirin Use, and Mortality among Critically Ill Pandemic H1N1 Influenza Patients: an Exploratory Analysis

(2016) Holly Epperly et al.   JAPANESE JOURNAL OF INFECTIOUS DISEASES

How Regulatory T-Cell Induction by Statins May Impair Influenza Vaccine Immunogenicity and Effectiveness

(2016) Luca Mascitelli et al.   JOURNAL OF INFECTIOUS DISEASES

Effect of Statin Use on Influenza Vaccine Effectiveness

(2016) Huong Q. McLean et al.   JOURNAL OF INFECTIOUS DISEASES

Regulation of SIRT1 in aging: Roles in mitochondrial function and biogenesis

(2016) Yujia Yuan et al.   MECHANISMS OF AGEING AND DEVELOPMENT

How sex and age affect immune responses, susceptibility to infections, and response to vaccination

(2015) Carmen Giefing-Kröll et al.   AGING CELL

A shortened interval between vaccinations with the trivalent inactivated influenza vaccine increases responsiveness in the aged

(2015) Senthil Kannan et al.   Aging-US

International Laboratory Comparison of Influenza Microneutralization Assays for A(H1N1)pdm09, A(H3N2), and A(H5N1) Influenza Viruses by CONSISE

(2015) Karen L. Laurie et al.   Clinical and Vaccine Immunology

Low-dose aspirin use does not diminish the immune response to monovalent H1N1 influenza vaccine in older adults

(2015) M. L. JACKSON et al.   EPIDEMIOLOGY AND INFECTION

Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures

(2015) Helder I. Nakaya et al.   IMMUNITY

SIRT1 deacetylates RORγt and enhances Th17 cell generation

(2015) Hyung W. Lim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Influence of Statins on Influenza Vaccine Response in Elderly Individuals

(2015) Steven Black et al.   JOURNAL OF INFECTIOUS DISEASES

Impact of Statins on Influenza Vaccine Effectiveness Against Medically Attended Acute Respiratory Illness

(2015) Saad B. Omer et al.   JOURNAL OF INFECTIOUS DISEASES

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

BTLA expression declines on B cells of the aged and is associated with low responsiveness to the trivalent influenza vaccine

(2015) Senthil Kannan et al.   Oncotarget

Circulating CXCR5+PD-1+Response Predicts Influenza Vaccine Antibody Responses in Young Adults but not Elderly Adults

(2014) Ramin Sedaghat Herati et al.   JOURNAL OF IMMUNOLOGY

Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release

(2014) Dmitry B. Zorov et al.   PHYSIOLOGICAL REVIEWS

Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion

(2014) Katsuhiko Warita et al.   Scientific Reports

Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function

(2013) Madhusudhanan Sukumar et al.   JOURNAL OF CLINICAL INVESTIGATION

Mammalian Sirt1: insights on its biological functions

(2011) Shahedur Rahman et al.   Cell Communication and Signaling

Mechanisms for the anti-inflammatory effects of statins

(2011) De-xiu Bu et al.   CURRENT OPINION IN LIPIDOLOGY

Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/ PD-L1 pathway

(2010) Celine S. Lages et al.   AGING CELL

AID-Induced Genotoxic Stress Promotes B Cell Differentiation in the Germinal Center via ATM and LKB1 Signaling

(2010) Mara H. Sherman et al.   MOLECULAR CELL

Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation

(2010) C. D. Klaassen et al.   PHARMACOLOGICAL REVIEWS

Ibuprofen and other widely used non-steroidal anti-inflammatory drugs inhibit antibody production in human cells

(2009) Simona Bancos et al.   CELLULAR IMMUNOLOGY

Effects of aging on B cell function

(2009) Daniela Frasca et al.   CURRENT OPINION IN IMMUNOLOGY

Inhibition of cyclooxygenase-2 impairs the expression of essential plasma cell transcription factors and human B-lymphocyte differentiation

(2009) Matthew P. Bernard et al.   IMMUNOLOGY

A metabolic switch to memory

(2009) Martin Prlic et al.   NATURE

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

(2009) Erika L. Pearce et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor α chain expression on activated B cells

(2008) Dianne Emslie et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses

(2008) Marcio O Lasaro et al.   NATURE MEDICINE

SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice

(2008) Gino Boily et al.   PLoS One

The antigen-specific memory CD8+ T-cell response induced by BCG in cattle resides in the CD8+γ/δTCR−CD45RO+ T-cell population

(2008) Alison E. Hogg et al.   VACCINE