Virtual memory cells make a major contribution to the response of aged influenza-naïve mice to influenza virus infection

Aging-related changes in human T-cell repertoire over 20 years delineated by deep sequencing of peripheral T-cell receptors

(2017) Kengo Yoshida et al.   EXPERIMENTAL GERONTOLOGY

The comparative immunology of wild and laboratory mice, Mus musculus domesticus

(2017) Stephen Abolins et al.   Nature Communications

Sequential Infection with Common Pathogens Promotes Human-like Immune Gene Expression and Altered Vaccine Response

(2016) Tiffany A. Reese et al.   Cell Host & Microbe

The life cycle of a T cell after vaccination - where does immune ageing strike?

(2016) C. Kim et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Normalizing the environment recapitulates adult human immune traits in laboratory mice

(2016) Lalit K. Beura et al.   NATURE

Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses

(2016) Vesna Pulko et al.   NATURE IMMUNOLOGY

Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner

(2016) Jason T. White et al.   Nature Communications

Figuring Fact from Fiction: Unbiased Polling of Memory T Cells

(2015) Carmen Gerlach et al.   CELL

Narrowing of Human Influenza A Virus-Specific T Cell Receptor α and β Repertoires with Increasing Age

(2015) Anna Gil et al.   JOURNAL OF VIROLOGY

Evaluation of non-reciprocal heterologous immunity between unrelated viruses

(2015) Jenny W. Che et al.   VIROLOGY

High-throughput sequencing insights into T-cell receptor repertoire diversity in aging

(2015) Jörg J. Goronzy et al.   Genome Medicine

Heterologous immunity between viruses

(2015) Raymond M. Welsh et al.   IMMUNOLOGICAL REVIEWS

Epitope-Specific Regulation of Memory Programming by Differential Duration of Antigen Presentation to Influenza-Specific CD8+ T Cells

(2014) André Ballesteros-Tato et al.   IMMUNITY

A population biological approach to understanding the maintenance and loss of the T-cell repertoire during aging

(2014) Philip L. F. Johnson et al.   IMMUNOLOGY

Clonal Expansions and Loss of Receptor Diversity in the Naive CD8 T Cell Repertoire of Aged Mice

(2014) M. Ahmed et al.   JOURNAL OF IMMUNOLOGY

Age-Related Decrease in TCR Repertoire Diversity Measured with Deep and Normalized Sequence Profiling

(2014) O. V. Britanova et al.   JOURNAL OF IMMUNOLOGY

Diversity and clonal selection in the human T-cell repertoire

(2014) Q. Qi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virus-Specific CD4+ Memory-Phenotype T Cells Are Abundant in Unexposed Adults

(2013) Laura F. Su et al.   IMMUNITY

Two Separate Defects Affecting True Naive or Virtual Memory T Cell Precursors Combine To Reduce Naive T Cell Responses with Aging

(2013) K. R. Renkema et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Central Memory CD8 T Cells in Aged Mice Are Virtual Memory Cells

(2013) B.-C. Chiu et al.   JOURNAL OF IMMUNOLOGY

Virtual memory CD8 T cells display unique functional properties

(2013) J.-Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Derivation and Maintenance of Virtual Memory CD8 T Cells

(2012) A. D. Akue et al.   JOURNAL OF IMMUNOLOGY

Defective CD8 T Cell Responses in Aged Mice Are Due to Quantitative and Qualitative Changes in Virus-Specific Precursors

(2012) V. Decman et al.   JOURNAL OF IMMUNOLOGY

Lifelong Persistent Viral Infection Alters the Naive T Cell Pool, Impairing CD8 T Cell Immunity in Late Life

(2012) M. J. Smithey et al.   JOURNAL OF IMMUNOLOGY

Early Priming Minimizes the Age-Related Immune Compromise of CD8+ T Cell Diversity and Function

(2012) Sophie A. Valkenburg et al.   PLoS Pathogens

Use it or lose it: establishment and persistence of T cell memory

(2012) Katherine Kedzierska et al.   Frontiers in Immunology

The narrowing of the CD8 T cell repertoire in old age

(2011) Marcia A Blackman et al.   CURRENT OPINION IN IMMUNOLOGY

Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions

(2011) B. D. Rudd et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative memory in the CD8 T cell lineage

(2011) You Jeong Lee et al.   TRENDS IN IMMUNOLOGY

Decline of influenza-specific CD8+ T cell repertoire in healthy geriatric donors

(2011) Jessica B Lee et al.   Immunity & Ageing

Nonmalignant Clonal Expansions of Memory CD8+ T Cells That Arise with Age Vary in Their Capacity To Mount Recall Responses to Infection

(2010) J. E. Kohlmeier et al.   JOURNAL OF IMMUNOLOGY

Loss of Naive T Cells and Repertoire Constriction Predict Poor Response to Vaccination in Old Primates

(2010) L. Cicin-Sain et al.   JOURNAL OF IMMUNOLOGY

The antigen-specific CD8+T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion

(2009) Catherine Haluszczak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Key role of T cell defects in age-related vulnerability to West Nile virus

(2009) James D. Brien et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Memory-Like CD8+ T Cells Generated during Homeostatic Proliferation Defer to Antigen-Experienced Memory Cells

(2009) K. P. Cheung et al.   JOURNAL OF IMMUNOLOGY

Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus

(2008) Eric J. Yager et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Age-related appearance of a CMV-specific high-avidity CD8+ T cell clonotype which does not occur in young adults

(2008) Angelika Schwanninger et al.   Immunity & Ageing