Mutations in chronic lymphocytic leukemia and how they affect therapy choice: focus on NOTCH1, SF3B1, and TP53
出版年份 2014 全文链接
标题
Mutations in chronic lymphocytic leukemia and how they affect therapy choice: focus on NOTCH1, SF3B1, and TP53
作者
关键词
-
出版物
Hematology-American Society of Hematology Education Program
Volume 2014, Issue 1, Pages 119-124
出版商
American Society of Hematology
发表日期
2014-11-25
DOI
10.1182/asheducation-2014.1.119
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial
- (2014) S. Stilgenbauer et al. BLOOD
- Notch signaling: switching an oncogene to a tumor suppressor
- (2014) C. Lobry et al. BLOOD
- Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia
- (2014) D. Rossi et al. BLOOD
- High-throughput sequencing for the identification ofNOTCH1mutations in early stage chronic lymphocytic leukaemia: biological and clinical implications
- (2014) Marta Lionetti et al. BRITISH JOURNAL OF HAEMATOLOGY
- ATM mutation rather than BIRC3 deletion and/or mutation predicts reduced survival in 11q-deleted chronic lymphocytic leukemia: data from the UK LRF CLL4 trial
- (2014) M. J. J. Rose-Zerilli et al. HAEMATOLOGICA
- Resistance Mechanisms for the Bruton's Tyrosine Kinase Inhibitor Ibrutinib
- (2014) Jennifer A. Woyach et al. NEW ENGLAND JOURNAL OF MEDICINE
- Patients with chronic lymphocytic leukaemia and clonal deletion of both 17p13.1 and 11q22.3 have a very poor prognosis
- (2013) Patricia T. Greipp et al. BRITISH JOURNAL OF HAEMATOLOGY
- Targeted resequencing for analysis of clonal composition of recurrent gene mutations in chronic lymphocytic leukaemia
- (2013) Alexander Jethwa et al. BRITISH JOURNAL OF HAEMATOLOGY
- Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia
- (2013) Dan A. Landau et al. CELL
- Clinical implications of the molecular genetics of chronic lymphocytic leukemia
- (2013) R. Foa et al. HAEMATOLOGICA
- Acquired Mutations That Affect Pre-mRNA Splicing in Hematologic Malignancies and Solid Tumors
- (2013) L. M. Scott et al. JNCI-Journal of the National Cancer Institute
- Prognostic impact and landscape of NOTCH1 mutations in chronic lymphocytic leukemia (CLL): a study on 852 patients
- (2013) S Weissmann et al. LEUKEMIA
- Functional impact of NOTCH1 mutations in chronic lymphocytic leukemia
- (2013) F Arruga et al. LEUKEMIA
- Cancer Genome Landscapes
- (2013) B. Vogelstein et al. SCIENCE
- High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations
- (2012) J. Edelmann et al. BLOOD
- Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia
- (2012) D. Rossi et al. BLOOD
- The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial
- (2012) D. G. Oscier et al. BLOOD
- Biallelic ATM Inactivation Significantly Reduces Survival in Patients Treated on the United Kingdom Leukemia Research Fund Chronic Lymphocytic Leukemia 4 Trial
- (2012) Anna Skowronska et al. JOURNAL OF CLINICAL ONCOLOGY
- ERIC recommendations on TP53 mutation analysis in chronic lymphocytic leukemia
- (2012) S Pospisilova et al. LEUKEMIA
- Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness
- (2011) D. Rossi et al. BLOOD
- Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia
- (2011) D. Rossi et al. BLOOD
- IAPs: Guardians of RIPK1
- (2011) M Darding et al. CELL DEATH AND DIFFERENTIATION
- Missense Mutations Located in Structural p53 DNA-Binding Motifs Are Associated With Extremely Poor Survival in Chronic Lymphocytic Leukemia
- (2011) Martin Trbusek et al. JOURNAL OF CLINICAL ONCOLOGY
- Analysis of the chronic lymphocytic leukemia coding genome: role ofNOTCH1mutational activation
- (2011) Giulia Fabbri et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
- (2011) Xose S. Puente et al. NATURE
- Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
- (2011) Víctor Quesada et al. NATURE GENETICS
- SF3B1and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia
- (2011) Lili Wang et al. NEW ENGLAND JOURNAL OF MEDICINE
- Understanding and Managing Ultra High-Risk Chronic Lymphocytic Leukemia
- (2011) S. Stilgenbauer et al. Hematology-American Society of Hematology Education Program
- Aggressive Chronic Lymphocytic Leukemia with Elevated Genomic Complexity Is Associated with Multiple Gene Defects in the Response to DNA Double-Strand Breaks
- (2010) P. Ouillette et al. CLINICAL CANCER RESEARCH
- Multiple roles of ATM in monitoring and maintaining DNA integrity
- (2010) Frederick A. Derheimer et al. FEBS LETTERS
- TP53Mutation and Survival in Chronic Lymphocytic Leukemia
- (2010) Thorsten Zenz et al. JOURNAL OF CLINICAL ONCOLOGY
- TP53 mutation profile in chronic lymphocytic leukemia: evidence for a disease specific profile from a comprehensive analysis of 268 mutations
- (2010) T Zenz et al. LEUKEMIA
- CD5+ B-cell lymphoproliferative disorders: Beyond chronic lymphocytic leukemia and mantle cell lymphoma
- (2010) Dragan Jevremovic et al. LEUKEMIA RESEARCH
- The Prognostic Value of TP53 Mutations in Chronic Lymphocytic Leukemia Is Independent of Del17p13: Implications for Overall Survival and Chemorefractoriness
- (2009) D. Rossi et al. CLINICAL CANCER RESEARCH
- Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells
- (2008) E. Rosati et al. BLOOD
- Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up
- (2008) T. Zenz et al. BLOOD
- The detection of TP53 mutations in chronic lymphocytic leukemia independently predicts rapid disease progression and is highly correlated with a complex aberrant karyotype
- (2008) F Dicker et al. LEUKEMIA
- Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer
- (2008) Martin F. Lavin NATURE REVIEWS MOLECULAR CELL BIOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started