Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia

The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation

(2011) D. Rossi et al.   BLOOD

Analysis of the chronic lymphocytic leukemia coding genome: role ofNOTCH1mutational activation

(2011) Giulia Fabbri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

(2011) Xose S. Puente et al.   NATURE

Understanding and Managing Ultra High-Risk Chronic Lymphocytic Leukemia

(2011) S. Stilgenbauer et al.   Hematology-American Society of Hematology Education Program

Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia

(2010) Maddalena Paganin et al.   BLOOD REVIEWS

NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CLL

(2010) Paolo Sportoletti et al.   BRITISH JOURNAL OF HAEMATOLOGY

Age at diagnosis and the utility of prognostic testing in patients with chronic lymphocytic leukemia

(2010) Tait D. Shanafelt et al.   CANCER

White blood cell count at diagnosis and immunoglobulin variable region gene mutations are independent predictors of treatment-free survival in young patients with stage A chronic lymphocytic leukemia

(2010) I. Del Giudice et al.   HAEMATOLOGICA

Multicentre validation of a prognostic index for overall survival in chronic lymphocytic leukaemia

(2010) Pietro Bulian et al.   HEMATOLOGICAL ONCOLOGY

Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies

(2010) Jon C Aster et al.   JOURNAL OF PATHOLOGY

Prognostic factors in chronic lymphocytic leukemia—what do we need to know?

(2010) Paula Cramer et al.   Nature Reviews Clinical Oncology

Improving survival in patients with chronic lymphocytic leukemia (1980-2008): the Hospital Clinic of Barcelona experience

(2009) P. Abrisqueta et al.   BLOOD

Monoallelic and biallelic inactivation of TP53 gene in chronic lymphocytic leukemia: selection, impact on survival, and response to DNA damage

(2009) J. Malcikova et al.   BLOOD

Stereotyped B-Cell Receptor Is an Independent Risk Factor of Chronic Lymphocytic Leukemia Transformation to Richter Syndrome

(2009) D. Rossi et al.   CLINICAL CANCER RESEARCH

The Prognostic Value of TP53 Mutations in Chronic Lymphocytic Leukemia Is Independent of Del17p13: Implications for Overall Survival and Chemorefractoriness

(2009) D. Rossi et al.   CLINICAL CANCER RESEARCH

Richter syndrome: molecular insights and clinical perspectives

(2009) Davide Rossi et al.   HEMATOLOGICAL ONCOLOGY

Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells

(2008) E. Rosati et al.   BLOOD

Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up

(2008) T. Zenz et al.   BLOOD

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

(2008) M. Hallek et al.   BLOOD

Validation of a new prognostic index for patients with chronic lymphocytic leukemia

(2008) Tait D. Shanafelt et al.   CANCER

Chronic lymphocytic leukaemia

(2008) G Dighiero et al.   LANCET

The detection of TP53 mutations in chronic lymphocytic leukemia independently predicts rapid disease progression and is highly correlated with a complex aberrant karyotype

(2008) F Dicker et al.   LEUKEMIA