Insights into the key determinants of membrane protein topology enable the identification of new monotopic folds

Membrane association of monotopic phosphoglycosyl transferase underpins function

(2018) Leah C. Ray et al.   Nature Chemical Biology

Bacterial phosphoglycosyl transferases: initiators of glycan biosynthesis at the membrane interface

(2017) Vinita Lukose et al.   GLYCOBIOLOGY

Analysis of a dual domain phosphoglycosyl transferase reveals a ping-pong mechanism with a covalent enzyme intermediate

(2017) Debasis Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein structure determination using metagenome sequence data

(2017) Sergey Ovchinnikov et al.   SCIENCE

Structural basis for dolichylphosphate mannose biosynthesis

(2017) Rosaria Gandini et al.   Nature Communications

Membranome: a database for proteome-wide analysis of single-pass membrane proteins

(2016) Andrei L. Lomize et al.   NUCLEIC ACIDS RESEARCH

Structure-guided enzymology of the lipid A acyltransferase LpxM reveals a dual activity mechanism

(2016) Dustin Dovala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interplay between hydrophobicity and the positive-inside rule in determining membrane-protein topology

(2016) Assaf Elazar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Rapid and Efficient Luminescence-based Method for Assaying Phosphoglycosyltransferase Enzymes

(2016) Debasis Das et al.   Scientific Reports

Conservation and Covariance in Small Bacterial Phosphoglycosyltransferases Identify the Functional Catalytic Core

(2015) Vinita Lukose et al.   BIOCHEMISTRY

Mechanisms of Integral Membrane Protein Insertion and Folding

(2015) Florian Cymer et al.   JOURNAL OF MOLECULAR BIOLOGY

The TOPCONS web server for consensus prediction of membrane protein topology and signal peptides

(2015) Konstantinos D. Tsirigos et al.   NUCLEIC ACIDS RESEARCH

Topological analysis of the Escherichia coli WcaJ protein reveals a new conserved configuration for the polyisoprenyl-phosphate hexose-1-phosphate transferase family

(2015) Sarah E. Furlong et al.   Scientific Reports

Robust and accurate prediction of residue–residue interactions across protein interfaces using evolutionary information

(2014) Sergey Ovchinnikov et al.   eLife

The transmembrane domain of caveolin-1 exhibits a helix–break–helix structure

(2012) Jinwoo Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Biochemical Characterization of the O-Linked Glycosylation Pathway inNeisseria gonorrhoeaeResponsible for Biosynthesis of Protein Glycans ContainingN,N′-Diacetylbacillosamine

(2011) Meredith D. Hartley et al.   BIOCHEMISTRY

Hydrogen-bond energetics drive helix formation in membrane interfaces

(2011) Paulo F. Almeida et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Flanking Residues Help Determine Whether a Hydrophobic Segment Adopts a Monotopic or Bitopic Topology in the Endoplasmic Reticulum Membrane

(2011) Morten H. H. Nørholm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

OPM database and PPM web server: resources for positioning of proteins in membranes

(2011) Mikhail A. Lomize et al.   NUCLEIC ACIDS RESEARCH

The Role of Proline in the Membrane Re-entrant Helix of Caveolin-1

(2010) Satoko Aoki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arginine in Membranes: The Connection Between Molecular Dynamics Simulations and Translocon-Mediated Insertion Experiments

(2010) Eric V. Schow et al.   JOURNAL OF MEMBRANE BIOLOGY

An Analysis of Reentrant Loops

(2010) Changhui Yan et al.   PROTEIN JOURNAL

Learning generative models for protein fold families

(2010) Sivaraman Balakrishnan et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis

(2009) Kazuharu Takeuchi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin

(2009) Markus Almén et al.   BMC BIOLOGY

Beyond triglyceride synthesis: the dynamic functional roles of MGAT and DGAT enzymes in energy metabolism

(2008) Yuguang Shi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mistranslation of Membrane Proteins and Two-Component System Activation Trigger Antibiotic-Mediated Cell Death

(2008) Michael A. Kohanski et al.   CELL

Determination of the Topology of the Hydrophobic Segment of Mammalian Diacylglycerol Kinase Epsilon in a Cell Membrane and Its Relationship to Predictions from Modeling

(2008) Marc Decaffmeyer et al.   JOURNAL OF MOLECULAR BIOLOGY

Distinct functional domains of the Salmonella enterica WbaP transferase that is involved in the initiation reaction for synthesis of the O antigen subunit

(2008) M. S. Saldias et al.   MICROBIOLOGY-SGM