Aurora kinase A localises to mitochondria to control organelle dynamics and energy production

Aurora kinase-A overexpression in mouse mammary epithelium induces mammary adenocarcinomas harboring genetic alterations shared with human breast cancer

(2016) Warapen Treekitkarnmongkol et al.   CARCINOGENESIS

Mitochondria and Cancer

(2016) Sejal Vyas et al.   CELL

Metabolic regulation of mitochondrial dynamics

(2016) Prashant Mishra et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial Dynamics and Metabolic Regulation

(2016) Timothy Wai et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype

(2016) Feimeng Zheng et al.   Nature Communications

A FRET biosensor reveals spatiotemporal activation and functions of aurora kinase A in living cells

(2016) Giulia Bertolin et al.   Nature Communications

What is the function of mitochondrial networks? A theoretical assessment of hypotheses and proposal for future research

(2015) Hanne Hoitzing et al.   BIOESSAYS

Adaptation of Cryo-Sectioning for IEM Labeling of Asymmetric Samples: A Study UsingCaenorhabditis elegans

(2015) Ophélie Nicolle et al.   TRAFFIC

Aurora Kinase Inhibitors: Current Status and Outlook

(2015) Vassilios Bavetsias et al.   Frontiers in Oncology

Aurora-A Expression Is Independently Associated with Chromosomal Instability in Colorectal Cancer

(2015) Yoshifumi Baba et al.   NEOPLASIA

Proteolytic Cleavage of Opa1 Stimulates Mitochondrial Inner Membrane Fusion and Couples Fusion to Oxidative Phosphorylation

(2014) Prashant Mishra et al.   Cell Metabolism

MitoTimer probe reveals the impact of autophagy, fusion, and motility on subcellular distribution of young and old mitochondrial protein and on relative mitochondrial protein age

(2013) Andrew W Ferree et al.   Autophagy

The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance

(2013) Giulia Bertolin et al.   Autophagy

Aurora A kinase negatively regulates Rho-kinase by phosphorylation in vivo

(2013) Woongjoon Moon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation

(2013) Kasturi Mitra   BIOESSAYS

Highly Improved Gene Targeting by Germline-Specific Cas9 Expression in Drosophila

(2013) Shu Kondo et al.   GENETICS

Bioenergetic role of mitochondrial fusion and fission

(2012) Benedikt Westermann   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Defective mitochondrial fusion, altered respiratory function, and distorted cristae structure in skin fibroblasts with heterozygous OPA1 mutations

(2012) Virginie Agier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

FRET microscopy in the living cell: Different approaches, strengths and weaknesses

(2012) Sergi Padilla-Parra et al.   BIOESSAYS

Molecular crosstalk between the proteasome, aggresomes and autophagy: Translational potential and clinical implications

(2012) James J. Driscoll et al.   CANCER LETTERS

Aurora A kinase (AURKA) in normal and pathological cell division

(2012) Anna S. Nikonova et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Colorectal adenoma to carcinoma progression is accompanied by changes in gene expression associated with ageing, chromosomal instability, and fatty acid metabolism

(2012) Beatriz Carvalho et al.   CELLULAR ONCOLOGY

High Lymph Node Yield is Related to Microsatellite Instability in Colon Cancer

(2011) E. J. Th. Belt et al.   ANNALS OF SURGICAL ONCOLOGY

Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ

(2011) Diana Whitaker-Menezes et al.   CELL CYCLE

TPX2andAURKApromote 20q amplicon-driven colorectal adenoma to carcinoma progression

(2011) Anke H Sillars-Hardebol et al.   GUT

RALA and RALBP1 regulate mitochondrial fission at mitosis

(2011) David F. Kashatus et al.   NATURE CELL BIOLOGY

A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma

(2010) G. Gorgun et al.   BLOOD

Weak mitochondrial targeting sequence determines tissue-specific subcellular localization of glutamine synthetase in liver and brain cells

(2010) G. D. Matthews et al.   JOURNAL OF CELL SCIENCE

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Global Analysis of the Mitochondrial N-Proteome Identifies a Processing Peptidase Critical for Protein Stability

(2009) F.-Nora Vögtle et al.   CELL

Importing Mitochondrial Proteins: Machineries and Mechanisms

(2009) Agnieszka Chacinska et al.   CELL

SLP-2 is required for stress-induced mitochondrial hyperfusion

(2009) Daniel Tondera et al.   EMBO JOURNAL

Hypothesis: Bifunctional mitochondrial proteins have centrosomal functions

(2009) Akilah Moore et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Aurora-A Phosphorylates, Activates, and Relocalizes the Small GTPase RalA

(2009) K.-H. Lim et al.   MOLECULAR AND CELLULAR BIOLOGY

An essential role of the aPKC–Aurora A–NDEL1 pathway in neurite elongation by modulation of microtubule dynamics

(2009) Daisuke Mori et al.   NATURE CELL BIOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells

(2009) K Zhu et al.   ONCOGENE

A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase

(2009) K. Mitra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of Aurora A (but Not Aurora B) Is Predictive of Survival in Breast Cancer

(2008) Y. Nadler et al.   CLINICAL CANCER RESEARCH

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

A Microtubule Interactome: Complexes with Roles in Cell Cycle and Mitosis

(2008) Julian R Hughes et al.   PLOS BIOLOGY