Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex

IL1- and TGFβ-Nox4 signaling, oxidative stress and DNA damage response are shared features of replicative, oncogene-induced, and drug-induced paracrine ‘Bystander senescence’

(2016) Sona Hubackova et al.   Aging-US

Quiescence-Induced LncRNAs Trigger H4K20 Trimethylation and Transcriptional Silencing

(2014) Holger Bierhoff et al.   MOLECULAR CELL

Telomeric transcripts stimulate telomere recombination to suppress senescence in cells lacking telomerase

(2014) Tai-Yuan Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1)

(2014) J Huang et al.   Cell Death & Disease

TBX3 Regulates Splicing In Vivo: A Novel Molecular Mechanism for Ulnar-Mammary Syndrome

(2014) Pavan Kumar P. et al.   PLoS Genetics

Senescence-associated lncRNAs: senescence-associated long noncoding RNAs

(2013) Kotb Abdelmohsen et al.   AGING CELL

p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes

(2013) Albert R. Davalos et al.   JOURNAL OF CELL BIOLOGY

The T-box Transcription Factors TBX2 and TBX3 in Mammary Gland Development and Breast Cancer

(2013) Nataki C. Douglas et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

The T-box transcription factor, TBX3, is sufficient to promote melanoma formation and invasion

(2013) Jade Peres et al.   Molecular Cancer

Long non-coding RNAs: new players in cell differentiation and development

(2013) Alessandro Fatica et al.   NATURE REVIEWS GENETICS

Mouse Tbx3 Mutants Suggest Novel Molecular Mechanisms for Ulnar-Mammary Syndrome

(2013) Deborah U. Frank et al.   PLoS One

Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination

(2013) Je-Hyun Yoon et al.   Nature Communications

p53 induces transcriptional and translational programs to suppress cell proliferation and growth

(2013) Fabricio Loayza-Puch et al.   GENOME BIOLOGY

Long non-coding RNA UCA1 regulated cell cycle distribution via CREB through PI3-K dependent pathway in bladder carcinoma cells

(2012) Chen Yang et al.   GENE

Wnt Antagonist SFRP1 Functions as a Secreted Mediator of Senescence

(2012) D. J. Elzi et al.   MOLECULAR AND CELLULAR BIOLOGY

The tRNA methyltransferase NSun2 stabilizes p16INK4 mRNA by methylating the 3′-untranslated region of p16

(2012) Xiaotian Zhang et al.   Nature Communications

TBX3 over-expression causes mammary gland hyperplasia and increases mammary stem-like cells in an inducible transgenic mouse model

(2011) Jing Liu et al.   BMC DEVELOPMENTAL BIOLOGY

Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16ink4a

(2011) Martin Kosar et al.   CELL CYCLE

Tumor Suppressor and Aging Biomarker p16INK4aInduces Cellular Senescence without the Associated Inflammatory Secretory Phenotype

(2011) Jean-Philippe Coppé et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis

(2011) D. U. Frank et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of mRNA decay in p53-induced gene expression

(2011) B. D. Melanson et al.   RNA

Regulation of the PML tumor suppressor in drug-induced senescence of human normal and cancer cells by JAK/STAT-mediated signaling

(2010) Sona Hubackova et al.   CELL CYCLE

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Transforming growth factor-beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth

(2010) Serif Senturk et al.   HEPATOLOGY

HuR Uses AUF1 as a Cofactor To Promote p16INK4 mRNA Decay

(2010) N. Chang et al.   MOLECULAR AND CELLULAR BIOLOGY

Estrogen Receptor Regulates E2F1 Expression to Mediate Tamoxifen Resistance

(2010) M. C. Louie et al.   MOLECULAR CANCER RESEARCH

Tbx3 improves the germ-line competency of induced pluripotent stem cells

(2010) Jianyong Han et al.   NATURE

Genetic Ablation of Caveolin-1 Drives Estrogen-Hypersensitivity and the Development of DCIS-Like Mammary Lesions

(2009) Isabelle Mercier et al.   AMERICAN JOURNAL OF PATHOLOGY

Functional Role of Transcriptional Factor TBX5 in Pre-mRNA Splicing and Holt-Oram Syndrome via Association with SC35

(2009) Chun Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Tbx3 Represses E-Cadherin Expression and Enhances Melanoma Invasiveness

(2008) M. Rodriguez et al.   CANCER RESEARCH

TBX3 Is Overexpressed in Breast Cancer and Represses p14ARF by Interacting with Histone Deacetylases

(2008) W. Yarosh et al.   CANCER RESEARCH

Database for mRNA Half-Life of 19 977 Genes Obtained by DNA Microarray Analysis of Pluripotent and Differentiating Mouse Embryonic Stem Cells

(2008) L. V. Sharova et al.   DNA RESEARCH

UCA1, a non-protein-coding RNA up-regulated in bladder carcinoma and embryo, influencing cell growth and promoting invasion

(2008) Fan Wang et al.   FEBS LETTERS

CAPER  Is a Novel Rel-TAD-Interacting Factor That Inhibits Lymphocyte Transformation by the Potent Rel/NF- B Oncoprotein v-Rel

(2008) J. Dutta et al.   JOURNAL OF VIROLOGY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

TBX3 and its splice variant TBX3 + exon 2a are functionally similar

(2008) Willem M.H. Hoogaars et al.   Pigment Cell & Melanoma Research