A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX

BH3 activation blocks Hdmx suppression of apoptosis and cooperates with Nutlin to induce cell death

(2011) Mark Wade et al.   CELL CYCLE

The relative contribution of pro-apoptotic p53-target genes in the triggering of apoptosis following DNA damage in vitro and in vivo

(2011) Kageaki Kuribayashi et al.   CELL CYCLE

PUMA cooperates with direct activator proteins to promote mitochondrial outer membrane permeabilization and apoptosis

(2010) Jerry E. Chipuk et al.   CELL CYCLE

Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding

(2010) N. P. Gomes et al.   GENES & DEVELOPMENT

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

A role for Chk1 in blocking transcriptional elongation of p21 RNA during the S-phase checkpoint

(2009) R. Beckerman et al.   GENES & DEVELOPMENT

Regulation of the p53 transcriptional response by structurally diverse core promoters

(2009) J. M. Morachis et al.   GENES & DEVELOPMENT

Essential role of the RNA-binding protein HuR in progenitor cell survival in mice

(2009) Mallika Ghosh et al.   JOURNAL OF CLINICAL INVESTIGATION

Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis

(2009) Hyungjin Kim et al.   MOLECULAR CELL

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

Mechanisms of regulatory diversity within the p53 transcriptional network

(2008) J M Espinosa   ONCOGENE