Membranes linked by trans-SNARE complexes require lipids prone to non-bilayer structure for progression to fusion

Fusion proteins and select lipids cooperate as membrane receptors for the solubleN-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) Vam7p.

(2013) Vidya Karunakaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The tethering complex HOPS catalyzes assembly of the soluble SNARE Vam7 into fusogenic trans-SNARE complexes

(2013) Michael Zick et al.   MOLECULAR BIOLOGY OF THE CELL

Lipid-Anchored SNAREs Lacking Transmembrane Regions Fully Support Membrane Fusion during Neurotransmitter Release

(2013) Peng Zhou et al.   NEURON

Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion

(2012) Jiajie Diao et al.   eLife

Membrane fusion catalyzed by a Rab, SNAREs, and SNARE chaperones is accompanied by enhanced permeability to small molecules and by lysis

(2011) Paola C. Zucchi et al.   MOLECULAR BIOLOGY OF THE CELL

In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release

(2011) M. Kyoung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A lipid-anchored SNARE supports membrane fusion

(2011) H. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane Fusion: Five Lipids, Four SNAREs, Three Chaperones, Two Nucleotides, and a Rab, All Dancing in a Ring on Yeast Vacuoles

(2010) William Wickner   Annual Review of Cell and Developmental Biology

Docking and Fast Fusion of Synaptobrevin Vesicles Depends on the Lipid Compositions of the Vesicle and the Acceptor SNARE Complex-Containing Target Membrane

(2010) Marta K. Domanska et al.   BIOPHYSICAL JOURNAL

Phosphoinositides Function Asymmetrically for Membrane Fusion, Promoting Tethering and 3Q-SNARE Subcomplex Assembly

(2010) Hao Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HOPS Initiates Vacuole Docking by Tethering Membranes before trans-SNARE Complex Assembly

(2010) Christopher M. Hickey et al.   MOLECULAR BIOLOGY OF THE CELL

The Major Role of the Rab Ypt7p in Vacuole Fusion Is Supporting HOPS Membrane Association

(2009) Christopher M. Hickey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Capture and release of partially zipped trans-SNARE complexes on intact organelles

(2009) Matthew L. Schwartz et al.   JOURNAL OF CELL BIOLOGY

Phosphoinositides and SNARE chaperones synergistically assemble and remodel SNARE complexes for membrane fusion

(2009) J. Mima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minimal membrane docking requirements revealed by reconstitution of Rab GTPase-dependent membrane fusion from purified components

(2009) C. Stroupe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstituted membrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperones

(2008) Joji Mima et al.   EMBO JOURNAL

The Janus-faced nature of the C2B domain is fundamental for synaptotagmin-1 function

(2008) Mingshan Xue et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Membrane fusion

(2008) William Wickner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY