Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios+ T cells and autoantibodies
出版年份 2013 全文链接
标题
Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios+ T cells and autoantibodies
作者
关键词
-
出版物
eLife
Volume 2, Issue -, Pages -
出版商
eLife Sciences Publications, Ltd
发表日期
2013-12-13
DOI
10.7554/elife.01020
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- (2013) Judith N. Mandl et al. IMMUNITY
- T-cell subsets in the germinal center
- (2013) Roybel R. Ramiscal et al. IMMUNOLOGICAL REVIEWS
- RasGRP1, but Not RasGRP3, Is Required for Efficient Thymic β-Selection and ERK Activation Downstream of CXCR4
- (2013) Dominic P. Golec et al. PLoS One
- Ras and extracellular signal-regulated kinase signaling in thymocytes and T cells
- (2013) Robert L. Kortum et al. TRENDS IN IMMUNOLOGY
- Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1
- (2013) Jeffrey S Iwig et al. eLife
- The Role of Ras Guanine Nucleotide Releasing Protein 4 in FcϵRI-mediated Signaling, Mast Cell Function, and T Cell Development
- (2012) Minghua Zhu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The translational landscape of mTOR signalling steers cancer initiation and metastasis
- (2012) Andrew C. Hsieh et al. NATURE
- Regulation of RasGRP1 Function in T Cell Development and Activation by Its Unique Tail Domain
- (2012) Deirdre M. Fuller et al. PLoS One
- Quantification of lymph node transit times reveals differences in antigen surveillance strategies of naive CD4+ and CD8+ T cells
- (2012) J. N. Mandl et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models
- (2012) T. D. Andrews et al. Open Biology
- Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner
- (2011) J. Wang et al. BLOOD
- Negative regulation of mTOR activation by diacylglycerol kinases
- (2011) B. K. Gorentla et al. BLOOD
- Anti-Islet Autoantibodies Trigger Autoimmune Diabetes in the Presence of an Increased Frequency of Islet-Reactive CD4 T Cells
- (2011) D. G. Silva et al. DIABETES
- ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes
- (2011) Mehmet Yabas et al. NATURE IMMUNOLOGY
- The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function
- (2011) Kai Yang et al. NATURE IMMUNOLOGY
- The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
- (2011) Greg M Delgoffe et al. NATURE IMMUNOLOGY
- Basal LAT-diacylglycerol-RasGRP1 Signals in T Cells Maintain TCRα Gene Expression
- (2011) Evan Markegard et al. PLoS One
- Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases
- (2011) Vincent Plagnol et al. PLoS Genetics
- Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production
- (2010) S. Zhang et al. BLOOD
- Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells
- (2010) A. M. Thornton et al. JOURNAL OF IMMUNOLOGY
- MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1
- (2010) W. Pan et al. JOURNAL OF IMMUNOLOGY
- Insights into the domain and repeat architecture of target of rapamycin
- (2010) Bruce A. Knutson JOURNAL OF STRUCTURAL BIOLOGY
- A map of human genome variation from population-scale sequencing
- (2010) Richard M. Durbin et al. NATURE
- The Use of Carboxyfluorescein Diacetate Succinimidyl Ester (CFSE) to Monitor Lymphocyte Proliferation
- (2010) Benjamin J. C. Quah et al. Jove-Journal of Visualized Experiments
- Functional links between diacylglycerol and phosphatidylinositol signaling systems in human leukocyte-derived cell lines
- (2009) Ho Y. Poon et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Membrane localization of RasGRP1 is controlled by an EF-hand, and by the GEF domain
- (2009) Ghazaleh Tazmini et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells
- (2009) Jayajit Das et al. CELL
- The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment
- (2009) Greg M. Delgoffe et al. IMMUNITY
- MAPK, Phosphatidylinositol 3-Kinase, and Mammalian Target of Rapamycin Pathways Converge at the Level of Ribosomal Protein S6 Phosphorylation to Control Metabolic Signaling in CD8 T Cells
- (2009) R. J. Salmond et al. JOURNAL OF IMMUNOLOGY
- Association of RASGRP1 with type 1 diabetes is revealed by combined follow-up of two genome-wide studies
- (2009) H Q Qu et al. JOURNAL OF MEDICAL GENETICS
- mTOR regulates memory CD8 T-cell differentiation
- (2009) Koichi Araki et al. NATURE
- Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production
- (2009) Katrina L Randall et al. NATURE IMMUNOLOGY
- K-RasG12D-induced T-cell lymphoblastic lymphoma/leukemias harbor Notch1 mutations and are sensitive to -secretase inhibitors
- (2008) T. Kindler et al. BLOOD
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